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Initially two rabbits were experimentally infected with <jats:italic>P. brasiliensis<\/jats:italic> and the humoral immune response was evaluated by <jats:styled-content style=\"fixed-case\">ELISA<\/jats:styled-content> using gp43 as antigen. The two animals showed IgG response against gp43 although no signs of disease were observed. The seroepidemiological study was carried out in 170 rabbits (free range <jats:italic>n<\/jats:italic>\u00a0=\u00a081 and caged <jats:italic>n<\/jats:italic>\u00a0=\u00a089) living in an endemic area for human paracoccidioidomycosis and a positivity of 27% was observed in the <jats:styled-content style=\"fixed-case\">ELISA<\/jats:styled-content> using gp43 as antigen. The free\u2010range rabbits showed a significantly higher positivity (34.6\u201351.7%) than the caged animals (11.1%). Sentinel rabbits exposed to natural infection with <jats:italic>P. brasiliensis<\/jats:italic> were followed up for 6\u00a0months and a seroconversion rate of 83.3% was observed. This is the first report of paracoccidioidomycosis in rabbits and suggests that this species can be useful sentinels for <jats:italic>P. brasiliensis<\/jats:italic> presence in the environment.<\/jats:p>","DOI":"10.1111\/myc.12146","type":"journal-article","created":{"date-parts":[[2013,10,14]],"date-time":"2013-10-14T11:53:12Z","timestamp":1381751592000},"page":"222-227","source":"Crossref","is-referenced-by-count":11,"title":["<i>Paracoccidioides brasiliensis<\/i> infection in domestic rabbits (<i>Oryctolagus cuniculus<\/i>)"],"prefix":"10.1111","volume":"57","author":[{"given":"Donizeti Rodrigues","family":"Belitardo","sequence":"first","affiliation":[{"name":"Departamento de Ci\u00eancias Patol\u00f3gicas Universidade Estadual de Londrina Londrina Brazil"}],"role":[{"role":"author","vocabulary":"crossref"}]},{"given":"Atilio Sersun","family":"Calefi","sequence":"additional","affiliation":[{"name":"Departamento de Ci\u00eancias Patol\u00f3gicas Universidade Estadual de Londrina 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