{"status":"ok","message-type":"work","message-version":"1.0.0","message":{"indexed":{"date-parts":[[2025,12,17]],"date-time":"2025-12-17T22:53:51Z","timestamp":1766012031211},"reference-count":23,"publisher":"Wiley","issue":"7","license":[{"start":{"date-parts":[[2014,1,19]],"date-time":"2014-01-19T00:00:00Z","timestamp":1390089600000},"content-version":"vor","delay-in-days":0,"URL":"http:\/\/onlinelibrary.wiley.com\/termsAndConditions#vor"}],"content-domain":{"domain":[],"crossmark-restriction":false},"short-container-title":["Mycoses"],"published-print":{"date-parts":[[2014,7]]},"abstract":"<jats:title>Summary<\/jats:title><jats:p>Surgery may improve the control of fungal disease and patient survival. The aim of this study was to report a single\u2010centre experience in using surgery for the treatment of paediatric invasive fungal infection (<jats:styled-content style=\"fixed-case\">IFI<\/jats:styled-content>). From 2001 to 2009, 18 paediatric onco\u2010haematology patients underwent 24 surgical procedures as treatment of <jats:styled-content style=\"fixed-case\">IFI<\/jats:styled-content>. At surgery, severe thrombocytopenia and neutropenia were present in four and one episodes respectively. Complications were one pleural effusion, one pleural effusion and surgical wound infection, one pneumothorax with wound dehiscence and one wound dehiscence. None of them required repeat surgery. The median duration of hospitalisation for four complicated procedures was 11\u00a0days, range 3\u201316, and 7\u00a0days, range 2\u201313, for the 20 uncomplicated procedures. No surgery\u2010related deaths occurred. Fourteen patients resumed chemotherapy after a median of 26\u00a0days, range 9\u201377, whereas nine patients underwent hematopoietic stem cell transplantation after a median of 42\u00a0days, range 27\u2013110. At 3\u00a0months from <jats:styled-content style=\"fixed-case\">IFI<\/jats:styled-content>, 17 patients were alive (94%) and one patient (6%) died from mycosis; the 3\u2010month overall survival (OS) being 94.4%, <jats:styled-content style=\"fixed-case\">CI<\/jats:styled-content> 66.6\u201399.2. After a median follow\u2010up of 7.1\u00a0years (<jats:styled-content style=\"fixed-case\">CI<\/jats:styled-content> 2.8\u20137.5), the <jats:styled-content style=\"fixed-case\">OS<\/jats:styled-content> was 54.5%, <jats:styled-content style=\"fixed-case\">CI<\/jats:styled-content> 29.2\u201374.2. Surgery is a feasible and valuable option in paediatric patients because it is associated with a low incidence of complications and an acceptable delay in resuming the chemotherapeutic plan.<\/jats:p>","DOI":"10.1111\/myc.12172","type":"journal-article","created":{"date-parts":[[2014,1,20]],"date-time":"2014-01-20T03:54:15Z","timestamp":1390190055000},"page":"394-399","source":"Crossref","is-referenced-by-count":7,"title":["The role of surgery in the treatment of invasive fungal infection in paediatric haematology patients: a retrospective single\u2010centre survey"],"prefix":"10.1111","volume":"57","author":[{"given":"Simone","family":"Cesaro","sequence":"first","affiliation":[{"name":"Pediatric Hematology Oncology Azienda Ospedaliera Universitaria Integrata Verona Italy"},{"name":"Pediatric Hematology Oncology Department of Pediatrics University of Padova Padova Italy"}],"role":[{"role":"author","vocabulary":"crossref"}]},{"given":"Anna","family":"Pegoraro","sequence":"additional","affiliation":[{"name":"Pediatric Hematology Oncology Azienda Ospedaliera Universitaria Integrata Verona Italy"},{"name":"Pediatric Hematology Oncology Department of Pediatrics University of Padova Padova Italy"}],"role":[{"role":"author","vocabulary":"crossref"}]},{"given":"Gloria","family":"Tridello","sequence":"additional","affiliation":[{"name":"Pediatric Hematology Oncology Azienda Ospedaliera Universitaria Integrata Verona Italy"},{"name":"Pediatric Hematology Oncology Department of Pediatrics University of Padova Padova Italy"}],"role":[{"role":"author","vocabulary":"crossref"}]},{"given":"Marta","family":"Pillon","sequence":"additional","affiliation":[{"name":"Pediatric Hematology Oncology Department of Pediatrics University of Padova Padova Italy"}],"role":[{"role":"author","vocabulary":"crossref"}]},{"given":"Elisa","family":"Cannata","sequence":"additional","affiliation":[{"name":"Pediatric Hematology Oncology Azienda Ospedaliera Universitaria Integrata Verona Italy"}],"role":[{"role":"author","vocabulary":"crossref"}]},{"given":"Stefano","family":"Faggin","sequence":"additional","affiliation":[{"name":"Pediatric Neuro Surgery Women's and Children's Health Department University of Padova Padova Italy"}],"role":[{"role":"author","vocabulary":"crossref"}]},{"given":"Giovanni","family":"Cecchetto","sequence":"additional","affiliation":[{"name":"Pediatric Surgery Women's and Children's Health Department University of Padova Padova 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