{"status":"ok","message-type":"work","message-version":"1.0.0","message":{"indexed":{"date-parts":[[2026,10,5]],"date-time":"2026-10-05T22:24:31Z","timestamp":1791239071430,"version":"4.1.0"},"reference-count":40,"publisher":"Wiley","issue":"10","license":[{"start":{"date-parts":[[2014,6,30]],"date-time":"2014-06-30T00:00:00Z","timestamp":1404086400000},"content-version":"vor","delay-in-days":0,"URL":"http:\/\/onlinelibrary.wiley.com\/termsAndConditions#vor"}],"content-domain":{"domain":[],"crossmark-restriction":false},"short-container-title":["Mycoses"],"published-print":{"date-parts":[[2014,10]]},"abstract":"<jats:title>Summary<\/jats:title><jats:p><jats:italic>Cryptococcus gattii<\/jats:italic>, a species belonging to the <jats:italic>Cryptococcus<\/jats:italic> complex which occurs endemically in tropical and subtropical regions, has been reported as a causative agent of cryptococcosis in healthy individuals. We report a case of meningitis in <jats:styled-content style=\"fixed-case\">HIV<\/jats:styled-content>\u2010negative patient from Cuiaba, <jats:styled-content style=\"fixed-case\">MT<\/jats:styled-content>, in the Midwestern region of Brazil. <jats:italic>Cryptococcus gattii <\/jats:italic><jats:styled-content style=\"fixed-case\">AFLP<\/jats:styled-content>6\/<jats:styled-content style=\"fixed-case\">VGII<\/jats:styled-content> was isolated from cerebrospinal fluid and molecular typing was performed by <jats:italic><jats:styled-content style=\"fixed-case\">URA<\/jats:styled-content>5<\/jats:italic>\u2010<jats:styled-content style=\"fixed-case\">RFLP<\/jats:styled-content>. The <jats:italic>in vitro<\/jats:italic> susceptibility profile was determined using the standard method according to the document M27A3, <jats:styled-content style=\"fixed-case\">CLSI<\/jats:styled-content> 2008. <jats:italic>C. gattii <\/jats:italic><jats:styled-content style=\"fixed-case\">AFLP<\/jats:styled-content>6\/<jats:styled-content style=\"fixed-case\">VGII<\/jats:styled-content> was shown to be susceptible to the antifungals tested. Treatment with 0.8\u00a0mg\/kg of amphotericin B was initiated; however, the patient died 2 days after the onset of therapy.<\/jats:p>","DOI":"10.1111\/myc.12210","type":"journal-article","created":{"date-parts":[[2014,7,2]],"date-time":"2014-07-02T03:49:30Z","timestamp":1404272970000},"page":"639-643","source":"Crossref","is-referenced-by-count":14,"title":["Fatal <i>Cryptococcus gattii<\/i> genotype <scp>AFLP<\/scp>6\/<scp>VGII<\/scp> infection in a <scp>HIV<\/scp>\u2010negative patient: case report and a literature review"],"prefix":"10.1111","volume":"57","author":[{"given":"Olivia Cometti","family":"Favalessa","sequence":"first","affiliation":[{"name":"Laborat\u00f3rio de Micologia Faculdade de Medicina Universidade Federal de Mato Grosso Cuiab\u00e1 MT Brazil"}],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"M\u00e1rcia dos Santos","family":"L\u00e1zera","sequence":"additional","affiliation":[{"name":"IPEC \u2013 Laborat\u00f3rio de Micologia FIOCRUZ Rio de Janeiro 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