{"status":"ok","message-type":"work","message-version":"1.0.0","message":{"indexed":{"date-parts":[[2026,7,16]],"date-time":"2026-07-16T03:26:55Z","timestamp":1784172415852,"version":"3.55.0"},"reference-count":9,"publisher":"Wiley","issue":"2","license":[{"start":{"date-parts":[[2015,1,15]],"date-time":"2015-01-15T00:00:00Z","timestamp":1421280000000},"content-version":"vor","delay-in-days":0,"URL":"http:\/\/onlinelibrary.wiley.com\/termsAndConditions#vor"}],"content-domain":{"domain":[],"crossmark-restriction":false},"short-container-title":["Mycoses"],"published-print":{"date-parts":[[2015,2]]},"abstract":"<jats:title>Summary<\/jats:title><jats:p>To date, there has been only one published report on the infectious sclerokeratitis caused by <jats:italic>Metarhizium anisopliae<\/jats:italic>, which is an entomopathogenic fungus. Regarding corneal infection, three reports have been published to date. Although the prognoses of the corneal infections are favourable, prognosis when scleral infection is involved is very poor. A 76\u2010year\u2010old patient presented with foreign body sensation in the left eye. Microscopic examination with Fungi Flora Y staining of the corneal scraping revealed fungal infection. The conjunctiva was melted by the infection over a wide area. Although intensive medications were administered, an emergency surgery was necessary because scleral thinning, corneal perforation and lens prolapse occurred. The fungal isolate was identified as <jats:italic>M. anisopliae<\/jats:italic> by sequencing the internal transcribed spacer region. Herein, we report the second known case worldwide of <jats:italic>M. anisopliae<\/jats:italic> sclerokeratitis, and we review the literature related to the ocular infections.<\/jats:p>","DOI":"10.1111\/myc.12279","type":"journal-article","created":{"date-parts":[[2015,1,15]],"date-time":"2015-01-15T17:57:03Z","timestamp":1421344623000},"page":"88-92","source":"Crossref","is-referenced-by-count":21,"title":["Severe fungal sclerokeratitis caused by <i>Metarhizium anisopliae<\/i>: a case report and literature review"],"prefix":"10.1111","volume":"58","author":[{"given":"Hiroshi","family":"Eguchi","sequence":"first","affiliation":[{"name":"Department of Ophthalmology Institute of Health Biosciences The University of Tokushima Graduate School Tokushima Japan"}],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Toshi","family":"Toibana","sequence":"additional","affiliation":[{"name":"Department of Ophthalmology Takamatsu Municipal Hospital Takamatsu Japan"}],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Fumika","family":"Hotta","sequence":"additional","affiliation":[{"name":"Department of Ophthalmology Institute of Health Biosciences The University of Tokushima Graduate School Tokushima Japan"}],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Tatsuro","family":"Miyamoto","sequence":"additional","affiliation":[{"name":"Department of Ophthalmology Institute of Health Biosciences The University of Tokushima Graduate School Tokushima Japan"}],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Yoshinori","family":"Mitamura","sequence":"additional","affiliation":[{"name":"Department of Ophthalmology Institute of Health Biosciences The University of Tokushima Graduate School Tokushima Japan"}],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Takashi","family":"Yaguchi","sequence":"additional","affiliation":[{"name":"Department of Mycosis Research Management Unit of Division of Bio\u2010resources Medical Mycology Research Center Chiba University Chiba Japan"}],"role":[{"vocabulary":"crossref","role":"author"}]}],"member":"311","published-online":{"date-parts":[[2015,1,15]]},"reference":[{"key":"e_1_2_5_2_1","first-page":"901","article-title":"Ocular surface temperature","volume":"8","author":"Efron N","year":"1989","journal-title":"Curr Eye Res"},{"key":"e_1_2_5_3_1","doi-asserted-by":"publisher","DOI":"10.1080\/02681219780001421"},{"key":"e_1_2_5_4_1","doi-asserted-by":"publisher","DOI":"10.1097\/00003226-200110000-00020"},{"key":"e_1_2_5_5_1","doi-asserted-by":"publisher","DOI":"10.1016\/j.jaapos.2010.12.003"},{"key":"e_1_2_5_6_1","doi-asserted-by":"publisher","DOI":"10.1097\/ICO.0b013e31815e9298"},{"key":"e_1_2_5_7_1","doi-asserted-by":"publisher","DOI":"10.3109\/02713688509000856"},{"key":"e_1_2_5_8_1","doi-asserted-by":"publisher","DOI":"10.1080\/09286580601001347"},{"key":"e_1_2_5_9_1","doi-asserted-by":"publisher","DOI":"10.1097\/00003226-200208000-00004"},{"key":"e_1_2_5_10_1","doi-asserted-by":"publisher","DOI":"10.1038\/sj.eye.6703099"}],"container-title":["Mycoses"],"original-title":[],"language":"en","link":[{"URL":"https:\/\/api.wiley.com\/onlinelibrary\/tdm\/v1\/articles\/10.1111%2Fmyc.12279","content-type":"unspecified","content-version":"vor","intended-application":"text-mining"},{"URL":"https:\/\/onlinelibrary.wiley.com\/doi\/pdf\/10.1111\/myc.12279","content-type":"unspecified","content-version":"vor","intended-application":"similarity-checking"}],"deposited":{"date-parts":[[2023,10,2]],"date-time":"2023-10-02T03:59:00Z","timestamp":1696219140000},"score":1,"resource":{"primary":{"URL":"https:\/\/onlinelibrary.wiley.com\/doi\/10.1111\/myc.12279"}},"subtitle":[],"short-title":[],"issued":{"date-parts":[[2015,1,15]]},"references-count":9,"journal-issue":{"issue":"2","published-print":{"date-parts":[[2015,2]]}},"alternative-id":["10.1111\/myc.12279"],"URL":"https:\/\/doi.org\/10.1111\/myc.12279","archive":["Portico"],"relation":{},"ISSN":["0933-7407","1439-0507"],"issn-type":[{"value":"0933-7407","type":"print"},{"value":"1439-0507","type":"electronic"}],"subject":[],"published":{"date-parts":[[2015,1,15]]}}}