{"status":"ok","message-type":"work","message-version":"1.0.0","message":{"indexed":{"date-parts":[[2026,2,27]],"date-time":"2026-02-27T02:53:01Z","timestamp":1772160781871,"version":"3.50.1"},"reference-count":26,"publisher":"Wiley","issue":"2","license":[{"start":{"date-parts":[[2015,1,15]],"date-time":"2015-01-15T00:00:00Z","timestamp":1421280000000},"content-version":"vor","delay-in-days":0,"URL":"http:\/\/onlinelibrary.wiley.com\/termsAndConditions#vor"}],"content-domain":{"domain":[],"crossmark-restriction":false},"short-container-title":["Mycoses"],"published-print":{"date-parts":[[2015,2]]},"abstract":"<jats:title>Summary<\/jats:title>\n                  <jats:p>\n                    Central nervous system trichosporonosis is a rare clinical entity and so far only six cases including three each of brain abscess and meningitis has been on record. We report a rare case of chronic meningo\u2010ventriculitis and intraventricular fungal ball due to\n                    <jats:italic>Trichosporon asahii<\/jats:italic>\n                    in an 18\u2010year\u2010old immunocompetent male from Burundi, east Africa. Neuroendoscopy showed multiple nodules and a fungal ball within the ventricle, which on culture grew\n                    <jats:italic>T. asahii<\/jats:italic>\n                    . He was initially empirically treated with liposomal amphotericin B. However, the antifungal susceptibility testing of\n                    <jats:italic>T. asahii<\/jats:italic>\n                    isolate revealed high minimum inhibitory concentration for amphotericin B (2\u00a0\u03bcg\u00a0ml\n                    <jats:sup>\u22121<\/jats:sup>\n                    ), flucytosine (16\u00a0\u03bcg\u00a0ml\n                    <jats:sup>\u22121<\/jats:sup>\n                    ) and caspofungin (2\u00a0\u03bcg\u00a0ml\n                    <jats:sup>\u22121<\/jats:sup>\n                    ) but exhibited potent activity for voriconazole, posaconazole, itraconazole and fluconazole. The patient rapidly succumbed to cardiac arrest before antifungal therapy could be changed. Although disseminated trichosporonosis has been increasingly reported the diagnosis represents a challenge especially in rare clinical settings such as intraventricular fungal ball in the present case, which has not been described previously.\n                  <\/jats:p>","DOI":"10.1111\/myc.12282","type":"journal-article","created":{"date-parts":[[2015,1,15]],"date-time":"2015-01-15T13:07:44Z","timestamp":1421327264000},"page":"99-103","source":"Crossref","is-referenced-by-count":13,"title":["<i>Trichosporon asahii<\/i>\n                    infection presenting as chronic meningo\u2010ventriculitis and intra ventricular fungal ball: a case report and literature review"],"prefix":"10.1111","volume":"58","author":[{"given":"Anil","family":"Kumar","sequence":"first","affiliation":[{"name":"Department of Microbiology Amrita Institute of Medical Sciences Kochi Kerala India"}],"role":[{"role":"author","vocabulary":"crossref"}]},{"given":"Suhas","family":"Udayakumaran","sequence":"additional","affiliation":[{"name":"Department of Neurosurgery Amrita Institute of Medical Sciences Kochi Kerala India"}],"role":[{"role":"author","vocabulary":"crossref"}]},{"given":"Rachana","family":"Babu","sequence":"additional","affiliation":[{"name":"Department of Microbiology Amrita Institute of Medical Sciences Kochi Kerala India"}],"role":[{"role":"author","vocabulary":"crossref"}]},{"given":"Bindhu M.","family":"Rajamma","sequence":"additional","affiliation":[{"name":"Department of Pathology Amrita Institute of Medical Sciences Kochi Kerala India"}],"role":[{"role":"author","vocabulary":"crossref"}]},{"given":"Anupam","family":"Prakash","sequence":"additional","affiliation":[{"name":"Department of Medical Mycology Vallabhbhai Patel Chest Institute University of Delhi Delhi India"}],"role":[{"role":"author","vocabulary":"crossref"}]},{"given":"Dilip","family":"Panikar","sequence":"additional","affiliation":[{"name":"Department of Neurosurgery Amrita Institute of Medical Sciences Kochi Kerala India"}],"role":[{"role":"author","vocabulary":"crossref"}]},{"given":"Shamsul","family":"Karim","sequence":"additional","affiliation":[{"name":"Department of Microbiology Amrita Institute of Medical Sciences Kochi Kerala India"}],"role":[{"role":"author","vocabulary":"crossref"}]},{"given":"Anuradha","family":"Chowdhary","sequence":"additional","affiliation":[{"name":"Department of Medical Mycology Vallabhbhai Patel Chest Institute University of Delhi Delhi India"}],"role":[{"role":"author","vocabulary":"crossref"}]}],"member":"311","published-online":{"date-parts":[[2015,1,15]]},"reference":[{"key":"e_1_2_4_2_1","doi-asserted-by":"publisher","DOI":"10.1128\/CMR.00003-11"},{"key":"e_1_2_4_3_1","doi-asserted-by":"publisher","DOI":"10.1007\/BF01963845"},{"key":"e_1_2_4_4_1","doi-asserted-by":"publisher","DOI":"10.1111\/j.1439-0507.2004.01062.x"},{"key":"e_1_2_4_5_1","doi-asserted-by":"publisher","DOI":"10.1111\/j.1600-0609.2010.01410.x"},{"key":"e_1_2_4_6_1","doi-asserted-by":"publisher","DOI":"10.1111\/j.1439-0507.1996.tb00124.x"},{"key":"e_1_2_4_7_1","doi-asserted-by":"publisher","DOI":"10.1046\/j.1439-0507.2003.00920.x"},{"key":"e_1_2_4_8_1","doi-asserted-by":"publisher","DOI":"10.1128\/JCM.05028-11"},{"key":"e_1_2_4_9_1","doi-asserted-by":"publisher","DOI":"10.1099\/00222615-3-1-191"},{"key":"e_1_2_4_10_1","doi-asserted-by":"publisher","DOI":"10.1111\/j.1439-0507.1995.tb00034.x"},{"key":"e_1_2_4_11_1","doi-asserted-by":"publisher","DOI":"10.4103\/0255-0857.31065"},{"key":"e_1_2_4_12_1","doi-asserted-by":"publisher","DOI":"10.5114\/ninp.2012.27180"},{"key":"e_1_2_4_13_1","volume-title":"Aids 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