{"status":"ok","message-type":"work","message-version":"1.0.0","message":{"indexed":{"date-parts":[[2025,10,30]],"date-time":"2025-10-30T11:28:32Z","timestamp":1761823712948},"reference-count":8,"publisher":"Wiley","issue":"5","license":[{"start":{"date-parts":[[2015,2,27]],"date-time":"2015-02-27T00:00:00Z","timestamp":1424995200000},"content-version":"vor","delay-in-days":0,"URL":"http:\/\/onlinelibrary.wiley.com\/termsAndConditions#vor"}],"content-domain":{"domain":[],"crossmark-restriction":false},"short-container-title":["Mycoses"],"published-print":{"date-parts":[[2015,5]]},"abstract":"<jats:title>Summary<\/jats:title><jats:p>A 65\u2010year\u2010old man developed Aspergillus brain abscesses following surgical resection of a sinus aspergilloma. He was treated with voriconazole for 1\u00a0year but infection recurred. We elected to treat with posaconazole delayed\u2010release tablets, currently only indicated as antifungal prophylaxis in high\u2010risk patients. A maintenance dose of 300\u00a0mg Q24\u00a0h resulted in a therapeutic serum concentration and appears safe and clinically effective thus far. This is the first report of successful use of posaconazole tablets for treatment of invasive aspergillosis.<\/jats:p>","DOI":"10.1111\/myc.12309","type":"journal-article","created":{"date-parts":[[2015,2,27]],"date-time":"2015-02-27T12:39:42Z","timestamp":1425040782000},"page":"313-314","source":"Crossref","is-referenced-by-count":7,"title":["Use of posaconazole delayed\u2010release tablets for treatment of invasive aspergillosis"],"prefix":"10.1111","volume":"58","author":[{"given":"Marjorie M.","family":"Conant","sequence":"first","affiliation":[{"name":"Division of Infectious Diseases Rush University Medical Center Chicago IL USA"}],"role":[{"role":"author","vocabulary":"crossref"}]},{"given":"Beverly E.","family":"Sha","sequence":"additional","affiliation":[{"name":"Division of Infectious Diseases Rush University Medical Center Chicago IL USA"}],"role":[{"role":"author","vocabulary":"crossref"}]},{"given":"Laurie A.","family":"Proia","sequence":"additional","affiliation":[{"name":"Division of Infectious Diseases Rush University Medical Center Chicago IL USA"}],"role":[{"role":"author","vocabulary":"crossref"}]}],"member":"311","published-online":{"date-parts":[[2015,2,27]]},"reference":[{"key":"e_1_2_2_2_1","volume-title":"Noxafil (posaconazole) Prescribing Information","author":"Merck & Co","year":"2013"},{"key":"e_1_2_2_3_1","doi-asserted-by":"publisher","DOI":"10.1016\/S1473-3099(05)70297-8"},{"key":"e_1_2_2_4_1","doi-asserted-by":"publisher","DOI":"10.2165\/00003495-200565110-00007"},{"key":"e_1_2_2_5_1","doi-asserted-by":"publisher","DOI":"10.1128\/AAC.50.2.658-666.2006"},{"key":"e_1_2_2_6_1","doi-asserted-by":"publisher","DOI":"10.1086\/508774"},{"key":"e_1_2_2_7_1","doi-asserted-by":"publisher","DOI":"10.1086\/503425"},{"key":"e_1_2_2_8_1","doi-asserted-by":"publisher","DOI":"10.1093\/jac\/dks268"},{"key":"e_1_2_2_9_1","doi-asserted-by":"publisher","DOI":"10.1128\/AAC.00222-12"}],"container-title":["Mycoses"],"original-title":[],"language":"en","link":[{"URL":"https:\/\/api.wiley.com\/onlinelibrary\/tdm\/v1\/articles\/10.1111%2Fmyc.12309","content-type":"unspecified","content-version":"vor","intended-application":"text-mining"},{"URL":"https:\/\/onlinelibrary.wiley.com\/doi\/pdf\/10.1111\/myc.12309","content-type":"unspecified","content-version":"vor","intended-application":"similarity-checking"}],"deposited":{"date-parts":[[2023,10,2]],"date-time":"2023-10-02T04:18:35Z","timestamp":1696220315000},"score":1,"resource":{"primary":{"URL":"https:\/\/onlinelibrary.wiley.com\/doi\/10.1111\/myc.12309"}},"subtitle":[],"short-title":[],"issued":{"date-parts":[[2015,2,27]]},"references-count":8,"journal-issue":{"issue":"5","published-print":{"date-parts":[[2015,5]]}},"alternative-id":["10.1111\/myc.12309"],"URL":"https:\/\/doi.org\/10.1111\/myc.12309","archive":["Portico"],"relation":{},"ISSN":["0933-7407","1439-0507"],"issn-type":[{"value":"0933-7407","type":"print"},{"value":"1439-0507","type":"electronic"}],"subject":[],"published":{"date-parts":[[2015,2,27]]}}}