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Moreover, overuse of antifungals may also lead to higher toxicity associated with unnecessary medication exposure and to increased healthcare costs. Antifungal stewardship (<jats:styled-content style=\"fixed-case\">AFS<\/jats:styled-content>) programmes consist of multidisciplinary interventions, led by specialists in infectious disease, microbiology and pharmacy that cooperate and communicate with the major prescribing departments in order to optimise antifungal therapies evaluating the indication, dose, streamlining and duration. Herein, we review the available evidence for the use of <jats:styled-content style=\"fixed-case\">AFS<\/jats:styled-content> and their impact on health economics. We also describe our <jats:styled-content style=\"fixed-case\">AFS<\/jats:styled-content> program, the successive steps we followed and the main difficulties we found.<\/jats:p>","DOI":"10.1111\/myc.12329","type":"journal-article","created":{"date-parts":[[2015,5,29]],"date-time":"2015-05-29T19:30:24Z","timestamp":1432927824000},"page":"14-25","source":"Crossref","is-referenced-by-count":90,"title":["Antifungal stewardship in daily practice and health economic implications"],"prefix":"10.1111","volume":"58","author":[{"given":"Patricia","family":"Mu\u00f1oz","sequence":"first","affiliation":[{"name":"Clinical Microbiology and Infectious Diseases Department Hospital General Universitario Gregorio Mara\u00f1\u00f3n Madrid Spain"},{"name":"Department of Medicine Complutense University of Madrid Madrid Spain"},{"name":"Instituto de Investigaci\u00f3n Sanitaria del Hospital Gregorio Mara\u00f1\u00f3n Madrid Spain"}],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Maricela","family":"Valerio","sequence":"additional","affiliation":[{"name":"Clinical Microbiology and Infectious Diseases Department Hospital General Universitario Gregorio Mara\u00f1\u00f3n Madrid Spain"},{"name":"Instituto de Investigaci\u00f3n Sanitaria del Hospital Gregorio Mara\u00f1\u00f3n Madrid Spain"}],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Antonio","family":"Vena","sequence":"additional","affiliation":[{"name":"Clinical Microbiology and Infectious Diseases Department Hospital General Universitario Gregorio Mara\u00f1\u00f3n Madrid Spain"},{"name":"Department of Medicine Complutense University of Madrid Madrid Spain"},{"name":"Instituto de Investigaci\u00f3n Sanitaria del Hospital Gregorio Mara\u00f1\u00f3n Madrid Spain"}],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Emilio","family":"Bouza","sequence":"additional","affiliation":[{"name":"Clinical Microbiology and 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