{"status":"ok","message-type":"work","message-version":"1.0.0","message":{"indexed":{"date-parts":[[2026,10,3]],"date-time":"2026-10-03T05:38:54Z","timestamp":1791005934796,"version":"4.1.0"},"reference-count":26,"publisher":"Wiley","issue":"7","license":[{"start":{"date-parts":[[2015,5,11]],"date-time":"2015-05-11T00:00:00Z","timestamp":1431302400000},"content-version":"vor","delay-in-days":0,"URL":"http:\/\/onlinelibrary.wiley.com\/termsAndConditions#vor"}],"content-domain":{"domain":[],"crossmark-restriction":false},"short-container-title":["Mycoses"],"published-print":{"date-parts":[[2015,7]]},"abstract":"Summary<\/jats:title>Few studies have evaluated the performance of serum galactomannan (GM) in patients with allergic bronchopulmonary aspergillosis (ABPA<\/jats:styled-content>). Herein, we analyse the diagnostic performance of serum GM in ABPA<\/jats:styled-content>. Consecutive subjects with ABPA<\/jats:styled-content> and asthma underwent GM estimation using the Platelia assay (Bio\u2010Rad Laboratories). An optical density index of >0.5 was considered positive. One hundred and twenty subjects (70 ABPA<\/jats:styled-content>, 50 asthma) with a mean (SD<\/jats:styled-content>) age of 33.0 (13.1) were included in the study. The serum GM<\/jats:styled-content> antigen was positive in 18 (25.7%) subjects with ABPA<\/jats:styled-content> compared to 9 (18%) subjects with asthma without ABPA<\/jats:styled-content> (P<\/jats:italic>\u00a0=\u00a00.32). The sensitivity of the serum GM<\/jats:styled-content> antigen test in patients with ABPA<\/jats:styled-content> was 25.7% [95% confidence intervals (CI<\/jats:styled-content>), 16\u201338] while the specificity was 82% (95% CI<\/jats:styled-content>, 69\u201391). The positive and negative predictive values were 66.7% (95% CI<\/jats:styled-content>, 46\u201384%) and 44.1% (95% CI<\/jats:styled-content>, 34\u201355), respectively. The area under the ROC<\/jats:styled-content> curve was 0.54 (95% CI<\/jats:styled-content>, 0.44\u20130.64). The sensitivity increased and the specificity decreased with decreasing the serum GM cutoff, and vice versa. The results of this study suggest that serum GM estimation has a limited role in the diagnostic workup of patients with ABPA<\/jats:styled-content>.<\/jats:p>","DOI":"10.1111\/myc.12334","type":"journal-article","created":{"date-parts":[[2015,5,11]],"date-time":"2015-05-11T08:19:26Z","timestamp":1431332366000},"page":"408-412","source":"Crossref","is-referenced-by-count":33,"title":["Performance of serum galactomannan in patients with allergic bronchopulmonary aspergillosis"],"prefix":"10.1111","volume":"58","author":[{"given":"Ritesh","family":"Agarwal","sequence":"first","affiliation":[{"name":"Department of Pulmonary Medicine Postgraduate Institute of Medical Education and Research (PGIMER) Chandigarh India"}],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Ashutosh N.","family":"Aggarwal","sequence":"additional","affiliation":[{"name":"Department of Pulmonary Medicine Postgraduate Institute of Medical Education and Research (PGIMER) Chandigarh India"}],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Inderpaul S.","family":"Sehgal","sequence":"additional","affiliation":[{"name":"Department of Pulmonary Medicine Postgraduate Institute of Medical Education and Research (PGIMER) Chandigarh India"}],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Sahajal","family":"Dhooria","sequence":"additional","affiliation":[{"name":"Department of Pulmonary Medicine Postgraduate Institute of Medical Education and Research (PGIMER) Chandigarh India"}],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Digambar","family":"Behera","sequence":"additional","affiliation":[{"name":"Department of Pulmonary Medicine Postgraduate Institute of Medical Education and Research (PGIMER) Chandigarh India"}],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Arunaloke","family":"Chakrabarti","sequence":"additional","affiliation":[{"name":"Department of Medical Microbiology Postgraduate Institute of Medical Education and Research (PGIMER) Chandigarh India"}],"role":[{"vocabulary":"crossref","role":"author"}]}],"member":"311","published-online":{"date-parts":[[2015,5,11]]},"reference":[{"key":"e_1_2_6_2_1","doi-asserted-by":"publisher","DOI":"10.1378\/chest.08-2586"},{"key":"e_1_2_6_3_1","doi-asserted-by":"publisher","DOI":"10.2217\/fmb.14.74"},{"key":"e_1_2_6_4_1","doi-asserted-by":"publisher","DOI":"10.1111\/cea.12141"},{"key":"e_1_2_6_5_1","doi-asserted-by":"publisher","DOI":"10.1111\/myc.12214"},{"key":"e_1_2_6_6_1","doi-asserted-by":"publisher","DOI":"10.1086\/588660"},{"key":"e_1_2_6_7_1","doi-asserted-by":"publisher","DOI":"10.1016\/j.rmed.2013.04.007"},{"key":"e_1_2_6_8_1","doi-asserted-by":"publisher","DOI":"10.1155\/2015\/943691"},{"key":"e_1_2_6_9_1","doi-asserted-by":"publisher","DOI":"10.1093\/cid\/cir179"},{"key":"e_1_2_6_10_1","doi-asserted-by":"publisher","DOI":"10.3109\/13693786.2011.615762"},{"key":"e_1_2_6_11_1","unstructured":"AgarwalR AggarwalAN GuptaD ChakrabartiA.Diagnostic value of serum galactomannan in allergic bronchopulmonary aspergillosis. 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