{"status":"ok","message-type":"work","message-version":"1.0.0","message":{"indexed":{"date-parts":[[2026,9,22]],"date-time":"2026-09-22T23:43:26Z","timestamp":1790120606541,"version":"4.0.1"},"reference-count":39,"publisher":"Wiley","issue":"8","license":[{"start":{"date-parts":[[2015,6,23]],"date-time":"2015-06-23T00:00:00Z","timestamp":1435017600000},"content-version":"vor","delay-in-days":0,"URL":"http:\/\/onlinelibrary.wiley.com\/termsAndConditions#vor"}],"funder":[{"name":"\u00d6sterreichische Nationalbank","award":["15346"],"award-info":[{"award-number":["15346"]}]}],"content-domain":{"domain":[],"crossmark-restriction":false},"short-container-title":["Mycoses"],"published-print":{"date-parts":[[2015,8]]},"abstract":"<jats:title>Summary<\/jats:title>\n                  <jats:p>\n                    We evaluated the performance of the\n                    <jats:italic>Aspergillus<\/jats:italic>\n                    \u2010specific lateral\u2010flow device (\n                    <jats:styled-content style=\"fixed-case\">LFD<\/jats:styled-content>\n                    ) test for diagnosing invasive pulmonary aspergillosis (\n                    <jats:styled-content style=\"fixed-case\">IPA<\/jats:styled-content>\n                    ) in patients with underlying haematological malignancies. Participating centres were the two Austrian University Hospitals of Graz and Innsbruck.\n                    <jats:styled-content style=\"fixed-case\">LFD<\/jats:styled-content>\n                    performance was evaluated with 95 bronchoalveolar lavage fluid (\n                    <jats:styled-content style=\"fixed-case\">BALF<\/jats:styled-content>\n                    ) samples from 72 patients collected prospectively in Graz, and with 24\n                    <jats:styled-content style=\"fixed-case\">BALF<\/jats:styled-content>\n                    bio bank samples from 23 patients (21 samples with probable\n                    <jats:styled-content style=\"fixed-case\">IPA<\/jats:styled-content>\n                    ) in Innsbruck. Invasive fungal infections were classified according to the revised European Organization of Research and Treatment of Cancer\/Mycoses Study Group criteria. Overall, 27 patients (30 samples) had probable\n                    <jats:styled-content style=\"fixed-case\">IPA<\/jats:styled-content>\n                    , 32 (43 samples) possible and 36 (46 samples) did not fulfil\n                    <jats:styled-content style=\"fixed-case\">IPA<\/jats:styled-content>\n                    criteria. The vast majority of patients \u2013 in particular those with probable\n                    <jats:styled-content style=\"fixed-case\">IPA<\/jats:styled-content>\n                    \u2013 received mould\u2010active treatment before bronchoscopy. Sensitivity, specificity, positive predictive value and negative\u2010predictive\u2010value for probable\n                    <jats:styled-content style=\"fixed-case\">IPA<\/jats:styled-content>\n                    diagnosis using the\n                    <jats:styled-content style=\"fixed-case\">BALF<\/jats:styled-content>\n                    \u2010\n                    <jats:styled-content style=\"fixed-case\">LFD<\/jats:styled-content>\n                    test were 71%, 76%, 35% and 94% for the Graz cohort. Sensitivity of the\n                    <jats:styled-content style=\"fixed-case\">BALF<\/jats:styled-content>\n                    \u2010\n                    <jats:styled-content style=\"fixed-case\">LFD<\/jats:styled-content>\n                    test for probable\n                    <jats:styled-content style=\"fixed-case\">IPA<\/jats:styled-content>\n                    was 57% in Innsbruck bio bank samples. Our results indicate that the\n                    <jats:styled-content style=\"fixed-case\">BALF<\/jats:styled-content>\n                    \u2010\n                    <jats:styled-content style=\"fixed-case\">LFD<\/jats:styled-content>\n                    \u2010test provides fast results with moderate sensitivities in patients with underlying haematological malignancies. Similar to other diagnostic tests and biomarkers sensitivity of the test may be influenced by ongoing systemic mould\u2010active treatment.\n                  <\/jats:p>","DOI":"10.1111\/myc.12343","type":"journal-article","created":{"date-parts":[[2015,6,23]],"date-time":"2015-06-23T08:41:27Z","timestamp":1435048887000},"page":"461-469","source":"Crossref","is-referenced-by-count":56,"title":["Diagnostic accuracy of the\n                    <i>Aspergillus<\/i>\n                    \u2010specific bronchoalveolar lavage lateral\u2010flow assay in haematological malignancy patients"],"prefix":"10.1111","volume":"58","author":[{"given":"Juergen","family":"Prattes","sequence":"first","affiliation":[{"name":"Section\u00a0of Infectious Diseases and Tropical Medicine Department of Internal Medicine Medical University of Graz Graz Austria"}],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Michaela","family":"Lackner","sequence":"additional","affiliation":[{"name":"Division of Hygiene and Medical Microbiology Innsbruck Medical University Innsbruck Austria"}],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Susanne","family":"Eigl","sequence":"additional","affiliation":[{"name":"Section\u00a0of Infectious Diseases and Tropical Medicine Department of Internal Medicine Medical University of Graz Graz Austria"},{"name":"Division of Pulmonology Department of Internal Medicine Medical University of Graz Graz Austria"}],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Frederike","family":"Reischies","sequence":"additional","affiliation":[{"name":"Section\u00a0of Infectious Diseases and Tropical Medicine Department of Internal Medicine Medical University of Graz Graz Austria"}],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Reinhard B.","family":"Raggam","sequence":"additional","affiliation":[{"name":"Clinical Institute of Medical and Chemical Laboratory Diagnostics Medical University of Graz Graz Austria"}],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Christoph","family":"Koidl","sequence":"additional","affiliation":[{"name":"Institute of Hygiene, Microbiology and Environmental Medicine Medical University of Graz Graz Austria"}],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Holger","family":"Flick","sequence":"additional","affiliation":[{"name":"Division of Pulmonology Department of Internal Medicine Medical University of Graz Graz Austria"}],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Robert","family":"Wurm","sequence":"additional","affiliation":[{"name":"Division of Pulmonology Department of Internal Medicine Medical University of Graz Graz Austria"}],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Michael","family":"Palfner","sequence":"additional","affiliation":[{"name":"Division of Pulmonology Department of Internal Medicine Medical University of Graz Graz 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