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Although fungal endocarditis rarely occur in newborns, it has a high morbidity and mortality. Antifungal therapy is often insufficient in cases who develop fungal endocarditis and surgical treatment is not preferred due to its difficulty and high mortality. Herein, fungal endocarditis in a preterm newborn treated with single\u2010dose recombinant tissue plasminogen activator in addition to antifungal therapy is presented and relevant literature has been reviewed. The vegetation completely disappeared following treatment and no complication was observed.<\/jats:p>","DOI":"10.1111\/myc.12359","type":"journal-article","created":{"date-parts":[[2015,7,27]],"date-time":"2015-07-27T14:23:05Z","timestamp":1438006985000},"page":"578-581","source":"Crossref","is-referenced-by-count":9,"title":["Treatment of neonatal fungal infective endocarditis with recombinant tissue plasminogen: activator in a low birth weight infant case report and review of the literature"],"prefix":"10.1111","volume":"58","author":[{"given":"Aslan","family":"Babayigit","sequence":"first","affiliation":[{"name":"Department of Neonatology Kanuni Sultan S\u00fcleyman Training and Research Hospital \u0130stanbul Turkey"}],"role":[{"role":"author","vocabulary":"crossref"}]},{"given":"Burcu","family":"Cebeci","sequence":"additional","affiliation":[{"name":"Department of Neonatology Kanuni Sultan S\u00fcleyman Training and Research Hospital \u0130stanbul 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