{"status":"ok","message-type":"work","message-version":"1.0.0","message":{"indexed":{"date-parts":[[2026,3,31]],"date-time":"2026-03-31T02:36:12Z","timestamp":1774924572319,"version":"3.50.1"},"reference-count":12,"publisher":"Wiley","issue":"10","license":[{"start":{"date-parts":[[2015,9,3]],"date-time":"2015-09-03T00:00:00Z","timestamp":1441238400000},"content-version":"vor","delay-in-days":0,"URL":"http:\/\/onlinelibrary.wiley.com\/termsAndConditions#vor"}],"content-domain":{"domain":[],"crossmark-restriction":false},"short-container-title":["Mycoses"],"published-print":{"date-parts":[[2015,10]]},"abstract":"<jats:title>Summary<\/jats:title><jats:p>The goal of this study was to report on the potential utility of cerebrospinal fluid (<jats:styled-content style=\"fixed-case\">CSF<\/jats:styled-content>) <jats:italic>Coccidioides<\/jats:italic> antigen testing in the diagnosis and management of <jats:italic>Coccidioides<\/jats:italic> meningitis. We retrospectively reviewed medical records of seven patients with <jats:italic>Coccidioides<\/jats:italic> meningitis who had <jats:italic>Coccidioides<\/jats:italic> antigen tests performed on <jats:styled-content style=\"fixed-case\">CSF<\/jats:styled-content>. In two severely immunocompromised patients, <jats:styled-content style=\"fixed-case\">CSF <\/jats:styled-content><jats:italic>Coccidioides<\/jats:italic> antigen testing was helpful in the diagnosis when other testing modalities were negative. <jats:italic>Coccidioides<\/jats:italic> antigen testing was also useful in the management of patients who had progression of disease due to non\u2010adherence, development of resistance, failure of therapy and the presence of vasculitis. Changing antigen levels helped identify disease complications in three patients that led to alterations in therapy or management. On the basis of our review of these seven patients with <jats:italic>Coccidioides<\/jats:italic> meningitis, we concluded that the <jats:italic>Coccidioides<\/jats:italic> antigen test contributed to the diagnosis and management of patients with <jats:italic>Coccidioides<\/jats:italic> meningitis.<\/jats:p>","DOI":"10.1111\/myc.12366","type":"journal-article","created":{"date-parts":[[2015,9,23]],"date-time":"2015-09-23T00:57:40Z","timestamp":1442969860000},"page":"598-602","source":"Crossref","is-referenced-by-count":23,"title":["Cerebrospinal fluid <i>Coccidioides<\/i> antigen testing in the diagnosis and management of central nervous system coccidioidomycosis"],"prefix":"10.1111","volume":"58","author":[{"given":"David M.","family":"Bamberger","sequence":"first","affiliation":[{"name":"University of Missouri\u2010Kansas City Kansas City MO USA"}],"role":[{"role":"author","vocabulary":"crossref"}]},{"given":"Brian S.","family":"Pepito","sequence":"additional","affiliation":[{"name":"University of Missouri\u2010Kansas City Kansas City MO USA"}],"role":[{"role":"author","vocabulary":"crossref"}]},{"given":"Laurie A.","family":"Proia","sequence":"additional","affiliation":[{"name":"Rush University School of Medicine Chicago IL USA"}],"role":[{"role":"author","vocabulary":"crossref"}]},{"given":"Luis","family":"Ostrosky\u2010Zeichner","sequence":"additional","affiliation":[{"name":"University of Texas\u2010Houston Houston TX USA"}],"role":[{"role":"author","vocabulary":"crossref"}]},{"given":"Madiha","family":"Ashraf","sequence":"additional","affiliation":[{"name":"University of Texas\u2010Houston Houston TX USA"}],"role":[{"role":"author","vocabulary":"crossref"}]},{"given":"Francisco","family":"Marty","sequence":"additional","affiliation":[{"name":"Brigham and Women's Hospital\/Harvard Medical School Boston MA USA"}],"role":[{"role":"author","vocabulary":"crossref"}]},{"given":"Eileen","family":"Scully","sequence":"additional","affiliation":[{"name":"Brigham and Women's Hospital\/Harvard Medical School Boston MA USA"}],"role":[{"role":"author","vocabulary":"crossref"}]},{"given":"L. Joseph","family":"Wheat","sequence":"additional","affiliation":[{"name":"MiraVista Diagnostics and MiraVista Technologies Indianapolis IN USA"}],"role":[{"role":"author","vocabulary":"crossref"}]}],"member":"311","published-online":{"date-parts":[[2015,9,3]]},"reference":[{"key":"e_1_2_7_2_1","first-page":"185","article-title":"Coccidioidomycosis: epidemiology","volume":"5","author":"Brown J","year":"2013","journal-title":"Clin Epidemiol"},{"key":"e_1_2_7_3_1","doi-asserted-by":"publisher","DOI":"10.1086\/497596"},{"key":"e_1_2_7_4_1","doi-asserted-by":"publisher","DOI":"10.1097\/MD.0b013e3181f378a8"},{"key":"e_1_2_7_5_1","doi-asserted-by":"publisher","DOI":"10.1007\/s11908-009-0043-1"},{"key":"e_1_2_7_6_1","doi-asserted-by":"publisher","DOI":"10.1093\/clinids\/14.3.673"},{"key":"e_1_2_7_7_1","doi-asserted-by":"publisher","DOI":"10.1086\/496991"},{"key":"e_1_2_7_8_1","doi-asserted-by":"publisher","DOI":"10.3201\/eid1901.120889"},{"key":"e_1_2_7_9_1","doi-asserted-by":"publisher","DOI":"10.1007\/s11046-006-0062-5"},{"key":"e_1_2_7_10_1","doi-asserted-by":"publisher","DOI":"10.1128\/CVI.00227-09"},{"key":"e_1_2_7_11_1","doi-asserted-by":"publisher","DOI":"10.7326\/0003-4819-119-1-199307010-00005"},{"key":"e_1_2_7_12_1","doi-asserted-by":"publisher","DOI":"10.1086\/592073"},{"key":"e_1_2_7_13_1","volume-title":"Use of Coccidioides Antigen in the Cerebrospinal Fluid for the Diagnosis of Coccidioidal Meningitis. Abstract M\u20101782","author":"Kassis C","year":"2014"}],"container-title":["Mycoses"],"original-title":[],"language":"en","link":[{"URL":"https:\/\/api.wiley.com\/onlinelibrary\/tdm\/v1\/articles\/10.1111%2Fmyc.12366","content-type":"unspecified","content-version":"vor","intended-application":"text-mining"},{"URL":"https:\/\/onlinelibrary.wiley.com\/doi\/pdf\/10.1111\/myc.12366","content-type":"unspecified","content-version":"vor","intended-application":"similarity-checking"}],"deposited":{"date-parts":[[2023,10,2]],"date-time":"2023-10-02T00:07:10Z","timestamp":1696205230000},"score":1,"resource":{"primary":{"URL":"https:\/\/onlinelibrary.wiley.com\/doi\/10.1111\/myc.12366"}},"subtitle":[],"short-title":[],"issued":{"date-parts":[[2015,9,3]]},"references-count":12,"journal-issue":{"issue":"10","published-print":{"date-parts":[[2015,10]]}},"alternative-id":["10.1111\/myc.12366"],"URL":"https:\/\/doi.org\/10.1111\/myc.12366","archive":["Portico"],"relation":{},"ISSN":["0933-7407","1439-0507"],"issn-type":[{"value":"0933-7407","type":"print"},{"value":"1439-0507","type":"electronic"}],"subject":[],"published":{"date-parts":[[2015,9,3]]}}}