{"status":"ok","message-type":"work","message-version":"1.0.0","message":{"indexed":{"date-parts":[[2023,10,30]],"date-time":"2023-10-30T19:10:27Z","timestamp":1698693027798},"reference-count":10,"publisher":"Wiley","issue":"2","license":[{"start":{"date-parts":[[2015,12,2]],"date-time":"2015-12-02T00:00:00Z","timestamp":1449014400000},"content-version":"vor","delay-in-days":0,"URL":"http:\/\/onlinelibrary.wiley.com\/termsAndConditions#vor"}],"funder":[{"DOI":"10.13039\/100004324","name":"Astellas Pharma US","doi-asserted-by":"publisher","id":[{"id":"10.13039\/100004324","id-type":"DOI","asserted-by":"publisher"}]},{"DOI":"10.13039\/100004334","name":"Merck","doi-asserted-by":"publisher","id":[{"id":"10.13039\/100004334","id-type":"DOI","asserted-by":"publisher"}]},{"DOI":"10.13039\/100004319","name":"Pfizer","doi-asserted-by":"publisher","id":[{"id":"10.13039\/100004319","id-type":"DOI","asserted-by":"publisher"}]}],"content-domain":{"domain":[],"crossmark-restriction":false},"short-container-title":["Mycoses"],"published-print":{"date-parts":[[2016,2]]},"abstract":"<jats:title>Summary<\/jats:title><jats:p>Cryptococcal infection is the third most common invasive fungal infection (<jats:styled-content style=\"fixed-case\">IFI<\/jats:styled-content>) among solid\u2010organ transplant (<jats:styled-content style=\"fixed-case\">SOT<\/jats:styled-content>) recipients and is considered an important opportunistic infection due to its significant morbidity and mortality. To determine whether a cluster of cryptococcosis in heart transplant patients was of nosocomial nature, three cases of orthotopic heart transplant recipients with postoperative disseminated cryptococcal infection were investigated and paired with an environmental survey in a tertiary care hospital. The infection prevention department conducted a multidisciplinary investigation, which did not demonstrate any evidence of health care\u2010associated environmental exposure. Moreover, multilocus sequence typing showed that one isolate was unique and the two others, although identical, were not temporally related and belong to the most common type seen in the Southern <jats:styled-content style=\"fixed-case\">US<\/jats:styled-content>. Additionally, all three patients had preexisting abnormalities of the <jats:styled-content style=\"fixed-case\">CT<\/jats:styled-content> chest scan and various degrees of acute and chronic rejection. Reactivation was suggested in all three patients. Screening methods may be useful to identify at risk patients and trigger a prophylactic or preemptive approach. However, more data is needed.<\/jats:p>","DOI":"10.1111\/myc.12433","type":"journal-article","created":{"date-parts":[[2015,12,2]],"date-time":"2015-12-02T07:46:17Z","timestamp":1449042377000},"page":"75-79","source":"Crossref","is-referenced-by-count":4,"title":["A pseudo\u2010outbreak of disseminated cryptococcal disease after orthotopic heart transplantation"],"prefix":"10.1111","volume":"59","author":[{"given":"E.","family":"Kennedy","sequence":"first","affiliation":[{"name":"Infection Prevention Department Memorial Hermann Texas Medical Center Houston TX USA"}],"role":[{"role":"author","vocabulary":"crossref"}]},{"given":"J.","family":"Vanichanan","sequence":"additional","affiliation":[{"name":"Division of Infectious Diseases UT Health Medical School at Houston Houston TX USA"}],"role":[{"role":"author","vocabulary":"crossref"}]},{"given":"I.","family":"Rajapreyar","sequence":"additional","affiliation":[{"name":"Program of Advanced Heart Failure UT Health Medical School at Houston 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