{"status":"ok","message-type":"work","message-version":"1.0.0","message":{"indexed":{"date-parts":[[2026,10,23]],"date-time":"2026-10-23T21:21:57Z","timestamp":1792790517947,"version":"4.5.0"},"reference-count":33,"publisher":"Wiley","issue":"8","license":[{"start":{"date-parts":[[2016,5,4]],"date-time":"2016-05-04T00:00:00Z","timestamp":1462320000000},"content-version":"vor","delay-in-days":0,"URL":"http:\/\/onlinelibrary.wiley.com\/termsAndConditions#vor"}],"funder":[{"DOI":"10.13039\/501100001411","name":"Indian Council of Medical Research","doi-asserted-by":"publisher","id":[{"id":"10.13039\/501100001411","id-type":"DOI","asserted-by":"publisher"}]}],"content-domain":{"domain":[],"crossmark-restriction":false},"short-container-title":["Mycoses"],"published-print":{"date-parts":[[2016,8]]},"abstract":"<jats:title>Summary<\/jats:title><jats:p>In Asian countries, <jats:italic>Trichosporon<\/jats:italic> infection is a well\u2010known disease in Japan. In India, the infection is increasingly recognised. The study was conducted to characterise the clinical <jats:italic>Trichosporon<\/jats:italic> isolates from India by phenotypic and molecular techniques. A total of 31 <jats:italic>Trichosporon<\/jats:italic> clinical isolates, recovered from patients of 14 hospitals across India were sequenced (ITS and IGS1 regions of rDNA). <jats:italic>In vitro<\/jats:italic> drug susceptibility testing of the isolates was performed against amphotericin\u2010B, fluconazole, itraconazole, voriconazole and posaconazole. IGS1, rather than ITS sequences, correctly identified the isolates: <jats:italic>Trichosporon asahii,<\/jats:italic> 20; <jats:italic>Trichosporon ovoides,<\/jats:italic> 3; <jats:italic>Trichosporon inkin,<\/jats:italic> 2; <jats:italic>Trichosporon asteroides,<\/jats:italic> 1; <jats:italic>Trichosporon mucoides,<\/jats:italic> 1; <jats:italic>Trichosporon loubieri,<\/jats:italic> 1; <jats:italic>Trichosporon debeurmannianum,<\/jats:italic> 1; and <jats:italic>Trichosporon dermatis,<\/jats:italic> 1. <jats:italic>Trichosporon asahii<\/jats:italic> genotype III was the most common type, followed by genotype I and VII. Both these targets did not help to identify one <jats:italic>Trichosporon<\/jats:italic> to the species level. <jats:italic>Trichosporon debeurmannianum, T. dermatis<\/jats:italic> and <jats:italic>T. asteroides<\/jats:italic> were isolated for the first time from a human disease in India. The minimum inhibitory concentrations for voriconazole and posaconazole were within effective range. The study highlights the presence of wide range of <jats:italic>Trichosporon<\/jats:italic> species causing infection in India. Voriconazole or posaconazole may be the better drugs to treat such patients.<\/jats:p>","DOI":"10.1111\/myc.12511","type":"journal-article","created":{"date-parts":[[2016,5,4]],"date-time":"2016-05-04T16:29:21Z","timestamp":1462379361000},"page":"528-534","source":"Crossref","is-referenced-by-count":27,"title":["Molecular characterisation and antifungal susceptibility of clinical <i>Trichosporon<\/i> isolates in India"],"prefix":"10.1111","volume":"59","author":[{"given":"Vijaylatha","family":"Rastogi","sequence":"first","affiliation":[{"name":"Department of Microbiology Jawaharlal Nehru Medical College and Associate Groups of Hospitals Ajmer India"}],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Prasanna","family":"Honnavar","sequence":"additional","affiliation":[{"name":"Mycology Division Department of Medical Microbiology Postgraduate Institute of Medical Education and Research (PGIMER) Chandigarh 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