{"status":"ok","message-type":"work","message-version":"1.0.0","message":{"indexed":{"date-parts":[[2026,9,15]],"date-time":"2026-09-15T00:30:11Z","timestamp":1789432211696,"version":"build-2803163510"},"reference-count":34,"publisher":"Wiley","issue":"11","license":[{"start":{"date-parts":[[2016,10,5]],"date-time":"2016-10-05T00:00:00Z","timestamp":1475625600000},"content-version":"vor","delay-in-days":0,"URL":"http:\/\/onlinelibrary.wiley.com\/termsAndConditions#vor"}],"content-domain":{"domain":[],"crossmark-restriction":false},"short-container-title":["Mycoses"],"published-print":{"date-parts":[[2016,11]]},"abstract":"<jats:title>Summary<\/jats:title><jats:p><jats:italic>Exophiala spinifera<\/jats:italic> is a dematiaceous fungus responsible for rare skin infections presenting as phaeohyphomycosis or chromoblastomycosis which has been primarily reported in tropical and subtropical areas (Asia, South and North America). We report the first case of <jats:italic>E.\u00a0spinifera<\/jats:italic> phaeohyphomycosis in a European patient. The phaeohyphomycosis was limited to the skin, involving the finger of an immunocompromised patient presenting with a large B\u2010cell lymphoma treated by R\u2010mini\u2010<jats:styled-content style=\"fixed-case\">CHOP<\/jats:styled-content> regimen. Remission was initially achieved by surgical excision; however, a local subcutaneous relapse required treatment with itraconazole. We performed a literature review of the 32 previously published cases of <jats:italic>E.\u00a0spinifera<\/jats:italic> phaeohyphomycosis highlighting its clinical phenotype: disseminated infection with extracutaneous involvement and poor prognosis were reported in young patients, of whom some were recently associated with <jats:italic><jats:styled-content style=\"fixed-case\">CARD<\/jats:styled-content>9<\/jats:italic> mutations, whereas cases in older immunocompromised patients were limited to the skin and showed better prognosis. There is currently no standard treatment for <jats:italic>E.\u00a0spinifera<\/jats:italic> phaeohyphomycosis; however, itraconazole, alone or in combination, allowed partial or complete response in 16 out of 20 cases.<\/jats:p>","DOI":"10.1111\/myc.12515","type":"journal-article","created":{"date-parts":[[2016,7,26]],"date-time":"2016-07-26T04:38:43Z","timestamp":1469507923000},"page":"691-696","source":"Crossref","is-referenced-by-count":15,"title":["Subcutaneous phaeohyphomycosis caused by <i>Exophiala spinifera<\/i> in a European patient with lymphoma: a rare occurrence case report and literature review"],"prefix":"10.1111","volume":"59","author":[{"given":"G.","family":"Bohelay","sequence":"first","affiliation":[{"name":"Department of Dermatology Avicenne Hospital Assistance Publique des H\u00f4pitaux de Paris (AP\u2010HP) Bobigny France"}],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"S.","family":"Robert","sequence":"additional","affiliation":[{"name":"Department 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