{"status":"ok","message-type":"work","message-version":"1.0.0","message":{"indexed":{"date-parts":[[2026,4,25]],"date-time":"2026-04-25T06:56:46Z","timestamp":1777100206703,"version":"3.51.4"},"reference-count":17,"publisher":"Wiley","issue":"2","license":[{"start":{"date-parts":[[2016,7,29]],"date-time":"2016-07-29T00:00:00Z","timestamp":1469750400000},"content-version":"vor","delay-in-days":0,"URL":"http:\/\/onlinelibrary.wiley.com\/termsAndConditions#vor"}],"content-domain":{"domain":[],"crossmark-restriction":false},"short-container-title":["Mycoses"],"published-print":{"date-parts":[[2017,2]]},"abstract":"<jats:title>Summary<\/jats:title><jats:p>In neutropenic patients, lungs are involved in 50%\u201380% of cases of fusariosis, but imaging of pulmonary fusariosis has been previously described as indistinguishable from other invasive mould diseases. Our attempt was to identify a radiological pattern that may distinguish pulmonary fusariosis from other mould diseases. We examined the <jats:styled-content style=\"fixed-case\">CT<\/jats:styled-content> findings of nine neutropenic haematology patients with invasive fusariosis. As control group for comparison, we examined 14 invasive mould diseases (11 aspergillosis, 3 mucormycosis) in haematology patients with similar underlying disease and timing of <jats:styled-content style=\"fixed-case\">CT<\/jats:styled-content> imaging. Chest\u2010<jats:styled-content style=\"fixed-case\">CT<\/jats:styled-content> in invasive fusariosis showed small airways (7\/9) or peribronchial (5\/9) infiltrates, less frequently macronodular consolidations (4\/9) with hypodense sign, but without halo sign or occluded\u2010vessel sign. The control group presented macronodular consolidations with occluded\u2010vessel sign in all of the cases; the halo and the hypodense signs were observed, respectively, in 100% and 82% of aspergillosis, and in 67% and 100% of mucormycosis. Sinusitis was documented by <jats:styled-content style=\"fixed-case\">CT<\/jats:styled-content> in 7\/7 fusariosis, 2\/2 mucormycosis and 5\/7 aspergillosis; maxillary and ethmoid sinuses were involved in 7\/7 fusariosis, in most of the cases with hyperdense opacification (rarely observed in the controls). We concluded that no radiological findings can discriminate between different mould infections, but invasive fusariosis should be suspected if chest\u2010<jats:styled-content style=\"fixed-case\">CT<\/jats:styled-content> demonstrates pulmonary infiltrates with the hypodense sign, but without the halo or the occluded\u2010vessel signs. Suspicion is greater in the presence of hyperdense maxillary and ethmoid sinusitis.<\/jats:p>","DOI":"10.1111\/myc.12538","type":"journal-article","created":{"date-parts":[[2017,1,13]],"date-time":"2017-01-13T06:51:04Z","timestamp":1484290264000},"page":"73-78","source":"Crossref","is-referenced-by-count":19,"title":["Radiologic findings of Fusarium pneumonia in neutropenic patients"],"prefix":"10.1111","volume":"60","author":[{"ORCID":"https:\/\/orcid.org\/0000-0002-7864-2586","authenticated-orcid":false,"given":"Claudia","family":"Sassi","sequence":"first","affiliation":[{"name":"Division of Radiology Department of Experimental Diagnostic and Specialty Medicine (DIMES) S. Orsola\u2010Malpighi Hospital University of Bologna  Bologna Italy"}],"role":[{"role":"author","vocabulary":"crossref"}]},{"given":"Marta","family":"Stanzani","sequence":"additional","affiliation":[{"name":"Department of Hematology and Oncology Institute of Hematology \u201cLorenzo e Ariosto Ser\u00e0gnoli\u201d S. Orsola\u2010Malpighi Hospital University of Bologna  Bologna Italy"}],"role":[{"role":"author","vocabulary":"crossref"}]},{"ORCID":"https:\/\/orcid.org\/0000-0002-2002-4339","authenticated-orcid":false,"given":"Russell E.","family":"Lewis","sequence":"additional","affiliation":[{"name":"Department of Internal Medicine Geriatrics and Nephrologic Diseases (DIMEC) Clinic of Infectious Diseases S. Orsola\u2010Malpighi Hospital University of Bologna  Bologna Italy"}],"role":[{"role":"author","vocabulary":"crossref"}]},{"given":"Nicola","family":"Vianelli","sequence":"additional","affiliation":[{"name":"Department of Hematology and Oncology Institute of Hematology \u201cLorenzo e Ariosto Ser\u00e0gnoli\u201d S. Orsola\u2010Malpighi Hospital University of Bologna  Bologna Italy"}],"role":[{"role":"author","vocabulary":"crossref"}]},{"given":"Andrea","family":"Tarsi","sequence":"additional","affiliation":[{"name":"Division of Radiology Department of Experimental Diagnostic and Specialty Medicine (DIMES) S. Orsola\u2010Malpighi Hospital University of Bologna  Bologna Italy"}],"role":[{"role":"author","vocabulary":"crossref"}]},{"given":"Antonio","family":"Poerio","sequence":"additional","affiliation":[{"name":"Division of Radiology Department of Experimental Diagnostic and Specialty Medicine (DIMES) S. Orsola\u2010Malpighi Hospital University of Bologna  Bologna Italy"}],"role":[{"role":"author","vocabulary":"crossref"}]},{"given":"Michele","family":"Cavo","sequence":"additional","affiliation":[{"name":"Department of Hematology and Oncology Institute of Hematology \u201cLorenzo e Ariosto Ser\u00e0gnoli\u201d S. Orsola\u2010Malpighi Hospital University of Bologna  Bologna Italy"}],"role":[{"role":"author","vocabulary":"crossref"}]},{"ORCID":"https:\/\/orcid.org\/0000-0003-3639-3494","authenticated-orcid":false,"given":"Giuseppe","family":"Battista","sequence":"additional","affiliation":[{"name":"Division of Radiology Department of Experimental Diagnostic and Specialty Medicine (DIMES) S. Orsola\u2010Malpighi Hospital University of Bologna  Bologna Italy"}],"role":[{"role":"author","vocabulary":"crossref"}]}],"member":"311","published-online":{"date-parts":[[2016,7,29]]},"reference":[{"key":"e_1_2_6_2_1","doi-asserted-by":"publisher","DOI":"10.1086\/432060"},{"key":"e_1_2_6_3_1","doi-asserted-by":"publisher","DOI":"10.1086\/522189"},{"key":"e_1_2_6_4_1","doi-asserted-by":"publisher","DOI":"10.1086\/651263"},{"key":"e_1_2_6_5_1","doi-asserted-by":"publisher","DOI":"10.1111\/myc.12081"},{"key":"e_1_2_6_6_1","doi-asserted-by":"publisher","DOI":"10.1128\/CMR.00014-07"},{"key":"e_1_2_6_7_1","doi-asserted-by":"publisher","DOI":"10.1086\/591969"},{"key":"e_1_2_6_8_1","first-page":"1165","article-title":"Update on the treatment of disseminated fusariosis: focus on voriconazole","volume":"3","author":"Stanzani M","year":"2007","journal-title":"Ther Clin Risk Manag"},{"key":"e_1_2_6_9_1","doi-asserted-by":"publisher","DOI":"10.1016\/j.jinf.2010.01.010"},{"key":"e_1_2_6_10_1","doi-asserted-by":"publisher","DOI":"10.1371\/journal.pone.0087784"},{"key":"e_1_2_6_11_1","doi-asserted-by":"publisher","DOI":"10.1093\/cid\/civ154"},{"key":"e_1_2_6_12_1","doi-asserted-by":"publisher","DOI":"10.1136\/thx.2010.157776"},{"key":"e_1_2_6_13_1","doi-asserted-by":"publisher","DOI":"10.2214\/AJR.07.3278"},{"key":"e_1_2_6_14_1","doi-asserted-by":"publisher","DOI":"10.1055\/s-0035-1562897"},{"key":"e_1_2_6_15_1","doi-asserted-by":"publisher","DOI":"10.1111\/1469-0691.12409"},{"key":"e_1_2_6_16_1","doi-asserted-by":"publisher","DOI":"10.1097\/QCO.0b013e328348b2e1"},{"key":"e_1_2_6_17_1","doi-asserted-by":"publisher","DOI":"10.1182\/blood.V90.3.999"},{"key":"e_1_2_6_18_1","doi-asserted-by":"publisher","DOI":"10.1148\/rg.275065189"}],"container-title":["Mycoses"],"original-title":[],"language":"en","link":[{"URL":"https:\/\/api.wiley.com\/onlinelibrary\/tdm\/v1\/articles\/10.1111%2Fmyc.12538","content-type":"application\/pdf","content-version":"vor","intended-application":"text-mining"},{"URL":"https:\/\/onlinelibrary.wiley.com\/doi\/pdf\/10.1111\/myc.12538","content-type":"unspecified","content-version":"vor","intended-application":"similarity-checking"}],"deposited":{"date-parts":[[2023,10,2]],"date-time":"2023-10-02T15:08:24Z","timestamp":1696259304000},"score":1,"resource":{"primary":{"URL":"https:\/\/onlinelibrary.wiley.com\/doi\/10.1111\/myc.12538"}},"subtitle":[],"short-title":[],"issued":{"date-parts":[[2016,7,29]]},"references-count":17,"journal-issue":{"issue":"2","published-print":{"date-parts":[[2017,2]]}},"alternative-id":["10.1111\/myc.12538"],"URL":"https:\/\/doi.org\/10.1111\/myc.12538","archive":["Portico"],"relation":{},"ISSN":["0933-7407","1439-0507"],"issn-type":[{"value":"0933-7407","type":"print"},{"value":"1439-0507","type":"electronic"}],"subject":[],"published":{"date-parts":[[2016,7,29]]}}}