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These patients are usually immunosuppressed, but immunocompetent hosts can be affected as well. <jats:italic>Candida albicans<\/jats:italic> is the most common pathogen. However, non\u2010albicans <jats:italic>Candida<\/jats:italic> species can cause deep skin invasion in rare circumstances. We report a case of deep cutaneous candidiasis caused by <jats:italic>Candida duobushaemulonii<\/jats:italic> in a 68\u2010year\u2010old man. Deep tissue invasion was confirmed by skin histopathology examination. The pathogen was initially identified as <jats:italic>C.\u00a0haemulonii<\/jats:italic> using the <jats:styled-content style=\"fixed-case\">VITEK<\/jats:styled-content><jats:sup>\u00ae<\/jats:sup> 2 system for microbial identification, but was later determined to be <jats:italic>C.\u00a0duobushaemulonii<\/jats:italic> based on sequencing of the internal transcribed spacer region of ribosomal <jats:styled-content style=\"fixed-case\">DNA<\/jats:styled-content> and D1\/D2 region of 26S <jats:styled-content style=\"fixed-case\">rDNA<\/jats:styled-content>. The patient was successfully treated with amphotericin B, followed by fluconazole and surgical intervention. To the best of our knowledge, this is the first case of deep cutaneous infection by <jats:italic>C.\u00a0duobushaemulonii<\/jats:italic>.<\/jats:p>","DOI":"10.1111\/myc.12540","type":"journal-article","created":{"date-parts":[[2016,9,7]],"date-time":"2016-09-07T11:57:49Z","timestamp":1473249469000},"page":"818-821","source":"Crossref","is-referenced-by-count":24,"title":["Primary deep cutaneous candidiasis caused by <i>Candida duobushaemulonii<\/i> in a 68\u2010year\u2010old man: the first case report and literature review"],"prefix":"10.1111","volume":"59","author":[{"ORCID":"https:\/\/orcid.org\/0000-0001-7297-8727","authenticated-orcid":false,"given":"Szu\u2010Yun","family":"Fang","sequence":"first","affiliation":[{"name":"Department of Dermatology Kaohsiung Veterans General Hospital  Kaohsiung Taiwan"}],"role":[{"role":"author","vocabulary":"crossref"}]},{"given":"Kai\u2010Che","family":"Wei","sequence":"additional","affiliation":[{"name":"Department of Dermatology Kaohsiung 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