{"status":"ok","message-type":"work","message-version":"1.0.0","message":{"indexed":{"date-parts":[[2026,7,18]],"date-time":"2026-07-18T00:56:45Z","timestamp":1784336205857,"version":"3.55.0"},"reference-count":65,"publisher":"Wiley","issue":"1","license":[{"start":{"date-parts":[[2016,8,26]],"date-time":"2016-08-26T00:00:00Z","timestamp":1472169600000},"content-version":"vor","delay-in-days":0,"URL":"http:\/\/onlinelibrary.wiley.com\/termsAndConditions#vor"}],"content-domain":{"domain":[],"crossmark-restriction":false},"short-container-title":["Mycoses"],"published-print":{"date-parts":[[2017,1]]},"abstract":"<jats:title>Summary<\/jats:title><jats:p>Cryptococcal meningitis is mainly caused by members of the <jats:italic>C.\u00a0neoformans\/C.\u00a0gattii<\/jats:italic> species complexes. The ecological niches of <jats:italic>Cryptococcus<\/jats:italic> species have extensively been studied, but its epidemiological relationship with meningitis cases is still unknown. In this study, we estimate the relationship between cryptococcal meningitis cases and tree and pigeon populations, the classical niches of members of <jats:italic>C.\u00a0neoformans<\/jats:italic>\/<jats:italic>C.\u00a0gattii sensu lato<\/jats:italic>. We analysed the records of every patient whose cerebrospinal fluid culture yielded <jats:italic>Cryptococcus<\/jats:italic> spp. during the last 30\u00a0years at Clinical Hospital of Curitiba. Data about Curitiba\u2032s pigeon and tree distribution were obtained from Curitiba\u2032s Secretaries of Zoonosis and Environment archives. We used ArcGis9 software to plot the distribution of the pigeon and tree populations in this city as well as cryptococcal meningitis cases, distinguishing them according to the causal agent in <jats:italic>C.\u00a0neoformans<\/jats:italic> or <jats:italic>C.\u00a0gattii s.l<\/jats:italic>. In total, 489 cryptococcal cultures were documented, with 140 corresponding to patients eligible for this study (134 affected by <jats:italic>C.\u00a0neoformans s.l<\/jats:italic>. and 6 by <jats:italic>C.\u00a0gattii s.l<\/jats:italic>.). The map showed a relationship between <jats:italic>C.\u00a0neoformans s.l<\/jats:italic>. patients and pigeon population. <jats:italic>C.\u00a0gattii s.l<\/jats:italic>. patients were associated with neither tree nor pigeon populations, but lived close to large unbuilt, unforested areas.<\/jats:p>","DOI":"10.1111\/myc.12550","type":"journal-article","created":{"date-parts":[[2016,8,26]],"date-time":"2016-08-26T05:27:37Z","timestamp":1472189257000},"page":"51-58","source":"Crossref","is-referenced-by-count":16,"title":["Geographic distribution of patients affected by <i>Cryptococcus neoformans<\/i>\/<i>Cryptococcus gattii<\/i> species complexes meningitis, pigeon and tree populations in Southern Brazil"],"prefix":"10.1111","volume":"60","author":[{"ORCID":"https:\/\/orcid.org\/0000-0002-7826-2452","authenticated-orcid":false,"given":"Tallulah","family":"Spina\u2010Tensini","sequence":"first","affiliation":[{"name":"Department of Neurology Clinical Hospital of Universidade Federal do Paran\u00e1  Curitiba Brazil"}],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Marisol Dominguez","family":"Muro","sequence":"additional","affiliation":[{"name":"Laboratory of Mycology Clinical Hospital of Universidade Federal do Paran\u00e1  Curitiba Brazil"}],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Fl\u00e1vio","family":"Queiroz\u2010Telles","sequence":"additional","affiliation":[{"name":"Infectious diseases Ambulatory Clinical Hospital of Universidade Federal do Paran\u00e1  Curitiba Brazil"}],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Isabella","family":"Strozzi","sequence":"additional","affiliation":[{"name":"Universidade Federal do Paran\u00e1  Curitiba Brazil"}],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Samia Talise","family":"Moraes","sequence":"additional","affiliation":[{"name":"Universidade Federal do Paran\u00e1  Curitiba Brazil"}],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Ricardo Rasmussen","family":"Petterle","sequence":"additional","affiliation":[{"name":"Health Sciences Section Universidade Federal do Paran\u00e1  Curitiba Brazil"}],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Marcelo","family":"Vettorello","sequence":"additional","affiliation":[{"name":"Municipal Health Secretary Curitiba City Hall  Curitiba Brazil"}],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Claudia","family":"Staudacher","sequence":"additional","affiliation":[{"name":"Zoonosis Control Centre Curitiba City Hall  Curitiba Brazil"}],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Luiz Alberto Lopes","family":"Miguez","sequence":"additional","affiliation":[{"name":"Geoprocessing Centre \u2013 SMMA Curitiba City Hall  Curitiba Brazil"}],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"S\u00e9rgio Monteiro","family":"de Almeida","sequence":"additional","affiliation":[{"name":"Department of Neuroinfections Clinical Hospital of Universidade Federal do Paran\u00e1  Curitiba Brazil"},{"name":"Instituto de Pesquisa Pel\u00e9 Pequeno Pr\u00edncipe Curitiba\u2010PR. 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