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The study sample consisted of 275 patients with laboratory\u2010confirmed Disseminated Histoplasmosis (<jats:styled-content style=\"fixed-case\">DH<\/jats:styled-content>)\/<jats:styled-content style=\"fixed-case\">AIDS<\/jats:styled-content>. The results showed that the prevalence of <jats:styled-content style=\"fixed-case\">DH<\/jats:styled-content> associated with <jats:styled-content style=\"fixed-case\">AIDS<\/jats:styled-content> was 4.4%. The majority of patients were young adult men with fever in 84.2%, cough in 63.4%, weight loss in 63.1%, diarrhoea in 44.8% and skin manifestations in 27.6% of patients. In the overall cohort, the <jats:styled-content style=\"fixed-case\">CD<\/jats:styled-content>4 counts were low, but not significantly different in survivors and non\u2010survivors. Higher levels of urea and lower levels of haemoglobin and platelets were observed in non\u2010survivor patients (&lt;.05). The global lethality was 71.3% (196\/275). The results with high prevalence and lethality highlight the need to adopt measures to facilitate early diagnosis, proper treatment and improved prognosis.<\/jats:p>","DOI":"10.1111\/myc.12551","type":"journal-article","created":{"date-parts":[[2016,9,14]],"date-time":"2016-09-14T09:16:38Z","timestamp":1473844598000},"page":"59-65","source":"Crossref","is-referenced-by-count":14,"title":["Prevalence and lethality among patients with histoplasmosis and <scp>AIDS<\/scp> in the Midwest Region of Brazil"],"prefix":"10.1111","volume":"60","author":[{"ORCID":"https:\/\/orcid.org\/0000-0002-9595-3319","authenticated-orcid":false,"given":"Tha\u00edsa C.","family":"Silva","sequence":"first","affiliation":[{"name":"Institute of Tropical Pathology and Public Health Federal University of Goi\u00e1s  Goiania Goi\u00e1s Brazil"}],"role":[{"role":"author","vocabulary":"crossref"}]},{"given":"Carolina M.","family":"Trem\u00e9a","sequence":"additional","affiliation":[{"name":"Institute of Tropical Pathology and Public Health Federal University of Goi\u00e1s  Goiania Goi\u00e1s Brazil"}],"role":[{"role":"author","vocabulary":"crossref"}]},{"given":"Ana Laura S. 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