{"status":"ok","message-type":"work","message-version":"1.0.0","message":{"indexed":{"date-parts":[[2026,3,1]],"date-time":"2026-03-01T05:18:02Z","timestamp":1772342282198,"version":"3.50.1"},"reference-count":37,"publisher":"Wiley","issue":"2","license":[{"start":{"date-parts":[[2016,9,29]],"date-time":"2016-09-29T00:00:00Z","timestamp":1475107200000},"content-version":"vor","delay-in-days":0,"URL":"http:\/\/onlinelibrary.wiley.com\/termsAndConditions#vor"}],"content-domain":{"domain":[],"crossmark-restriction":false},"short-container-title":["Mycoses"],"published-print":{"date-parts":[[2017,2]]},"abstract":"<jats:title>Summary<\/jats:title><jats:p>To describe the epidemiology of invasive <jats:italic>Candida<\/jats:italic> infection in a tertiary care paediatric hospital. Prospective single\u2010centre survey on all <jats:italic>Candida<\/jats:italic> strains isolated from normally sterile fluids and urines in the period 2005\u20102015 . A total of 299 <jats:styled-content style=\"fixed-case\">ICI<\/jats:styled-content> were documented in 262 patients. Urinary tract infection represented the most frequent diagnosis (62%), followed by fungaemia (34%) and peritonitis (4%). Fungaemia was most frequent in children with cancer (59%) or in low birth weight neonates (61%), while urinary tract infections were more frequent in patients with urinary tract malformation. <jats:italic>C.albicans<\/jats:italic> was the most frequently isolated species (60%) compared with <jats:italic>C<\/jats:italic>. non\u2010<jats:italic>albicans<\/jats:italic>, but differences were present according to the site of isolation and underlying conditions. Overall 90\u2010day mortality was 7%, 13% in fungaemias, 8% in peritonitis and 2% in urinary tract infections. The rates of invasive <jats:italic>Candida<\/jats:italic> infection increased during the study period. Invasive <jats:italic>Candida<\/jats:italic> infection is diagnosed with increasing frequency in children. Site of isolation and aetiology are frequently related with the presence of underlying, favouring conditions. Mortality was not negligible, especially in the presence of more invasive infections and specific underlying conditions.<\/jats:p>","DOI":"10.1111\/myc.12570","type":"journal-article","created":{"date-parts":[[2016,9,29]],"date-time":"2016-09-29T09:44:12Z","timestamp":1475142252000},"page":"118-123","source":"Crossref","is-referenced-by-count":22,"title":["<i>Candida<\/i> infections in paediatrics: Results from a prospective single\u2010centre study in a tertiary care children's hospital"],"prefix":"10.1111","volume":"60","author":[{"ORCID":"https:\/\/orcid.org\/0000-0003-0593-4112","authenticated-orcid":false,"given":"Alessio","family":"Mesini","sequence":"first","affiliation":[{"name":"Division of Infectious Diseases Department of Health Sciences University of Genoa  Genoa Italy"}],"role":[{"role":"author","vocabulary":"crossref"}]},{"given":"Roberto","family":"Bandettini","sequence":"additional","affiliation":[{"name":"Laboratory of Analysis Istituto Giannina Gaslini Children's 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