{"status":"ok","message-type":"work","message-version":"1.0.0","message":{"indexed":{"date-parts":[[2025,10,22]],"date-time":"2025-10-22T10:36:48Z","timestamp":1761129408087,"version":"3.37.3"},"reference-count":45,"publisher":"Wiley","issue":"7","license":[{"start":{"date-parts":[[2017,3,20]],"date-time":"2017-03-20T00:00:00Z","timestamp":1489968000000},"content-version":"vor","delay-in-days":0,"URL":"http:\/\/onlinelibrary.wiley.com\/termsAndConditions#vor"}],"content-domain":{"domain":[],"crossmark-restriction":false},"short-container-title":["Mycoses"],"published-print":{"date-parts":[[2017,7]]},"abstract":"<jats:title>Summary<\/jats:title><jats:p>Mucormycosis is a deadly invasive fungal infection and mainly affects immunocompromised patients. To investigate the clinical features of patients who developed mucormycosis and to determine the parameters, which influenced the outcome following mycotic infection. The current investigation retrospectively evaluated the demographic characteristics, clinical features, therapeutic data, as well as the outcomes of treatment in all cases of proven and probable mucormycosis diagnosed from 2002 until 2016 in our hospital. A total of thirty cases were recorded. <jats:italic>Rhizopus<\/jats:italic> spp. was the predominant pathogen among the identified Mucorales (26.7%). Diabetes mellitus (46.7%) and haematological malignancy (40%), were the most common underlying diseases. With regard to predisposing factors, neutropenia (43.3%) and chemotherapy (40%) were the leading concomitant parameters. The most frequent sites of infection were lung (30%) and sinus (26.7%), whereas disseminated infection was also found in nine of 30 patients (30%). Neutropenia remained the only independent factor associated with mortality (Relative Risk=3.557, 95% <jats:styled-content style=\"fixed-case\">CI<\/jats:styled-content>=1.365\u20109.271, <jats:italic>P<\/jats:italic>=.009). Diagnostic delay \u2010either due to delayed presentation of patients to our centre or insufficient awareness about invasive fungal infection among our clinicians\u2010 is a likely explanation for such a high mortality rate in our series.<\/jats:p>","DOI":"10.1111\/myc.12614","type":"journal-article","created":{"date-parts":[[2017,3,21]],"date-time":"2017-03-21T04:31:11Z","timestamp":1490070671000},"page":"426-432","source":"Crossref","is-referenced-by-count":16,"title":["Evaluation of 30 cases of mucormycosis at a university hospital in Iran"],"prefix":"10.1111","volume":"60","author":[{"given":"Reza","family":"Samarei","sequence":"first","affiliation":[{"name":"Department of Otolaryngology Faculty of Medicine Imam Khomeini Hospital Urmia University of Medical Sciences  Urmia Iran"}],"role":[{"role":"author","vocabulary":"crossref"}]},{"ORCID":"https:\/\/orcid.org\/0000-0001-7372-2256","authenticated-orcid":false,"given":"Naser","family":"Gharebaghi","sequence":"additional","affiliation":[{"name":"Department of Infectious Diseases Urmia University of Medical Sciences  Urmia Iran"}],"role":[{"role":"author","vocabulary":"crossref"}]},{"given":"Salar","family":"Zayer","sequence":"additional","affiliation":[{"name":"Department of Cardiology Urmia University of Medical Sciences  Urmia Iran"}],"role":[{"role":"author","vocabulary":"crossref"}]}],"member":"311","published-online":{"date-parts":[[2017,3,20]]},"reference":[{"key":"e_1_2_7_2_1","doi-asserted-by":"publisher","DOI":"10.1007\/s10096-006-0107-1"},{"key":"e_1_2_7_3_1","doi-asserted-by":"publisher","DOI":"10.1016\/j.mycres.2007.03.004"},{"key":"e_1_2_7_4_1","doi-asserted-by":"publisher","DOI":"10.3201\/eid1509.090334"},{"key":"e_1_2_7_5_1","doi-asserted-by":"publisher","DOI":"10.1111\/myc.12149"},{"key":"e_1_2_7_6_1","doi-asserted-by":"publisher","DOI":"10.1093\/cid\/cir880"},{"key":"e_1_2_7_7_1","doi-asserted-by":"publisher","DOI":"10.1086\/432579"},{"key":"e_1_2_7_8_1","doi-asserted-by":"publisher","DOI":"10.1093\/jac\/dkp430"},{"key":"e_1_2_7_9_1","doi-asserted-by":"publisher","DOI":"10.1111\/j.1469-0691.2010.03456.x"},{"key":"e_1_2_7_10_1","first-page":"573","article-title":"Invasive zygomycosis in India: experience in a tertiary care hospital","volume":"2009","author":"Chakrabarti A","journal-title":"Postgrad Med J"},{"key":"e_1_2_7_11_1","doi-asserted-by":"publisher","DOI":"10.1080\/13693780500464930"},{"key":"e_1_2_7_12_1","doi-asserted-by":"publisher","DOI":"10.1053\/jinf.2001.0831"},{"key":"e_1_2_7_13_1","doi-asserted-by":"publisher","DOI":"10.1007\/s12281-013-0152-z"},{"key":"e_1_2_7_14_1","doi-asserted-by":"publisher","DOI":"10.1128\/CMR.13.2.236"},{"key":"e_1_2_7_15_1","doi-asserted-by":"publisher","DOI":"10.1093\/jac\/dkm429"},{"key":"e_1_2_7_16_1","doi-asserted-by":"publisher","DOI":"10.1093\/cid\/cir866"},{"key":"e_1_2_7_17_1","doi-asserted-by":"publisher","DOI":"10.1086\/588660"},{"key":"e_1_2_7_18_1","doi-asserted-by":"publisher","DOI":"10.1097\/QCO.0b013e32834ab21e"},{"key":"e_1_2_7_19_1","doi-asserted-by":"publisher","DOI":"10.1016\/j.diabet.2012.01.002"},{"key":"e_1_2_7_20_1","first-page":"73","article-title":"Mucormycosis in Cairo, Egypt: review of 10 reported cases","volume":"52","author":"Zaki SM","year":"2014","journal-title":"Med Mycol"},{"key":"e_1_2_7_21_1","doi-asserted-by":"publisher","DOI":"10.1111\/myc.12278"},{"key":"e_1_2_7_22_1","first-page":"175","article-title":"Report of thirteen cases of mucormycosis","volume":"7","author":"Moghaddami M","year":"1993","journal-title":"Med J Islam Repub Iran"},{"key":"e_1_2_7_23_1","doi-asserted-by":"publisher","DOI":"10.1111\/myc.12474"},{"key":"e_1_2_7_24_1","doi-asserted-by":"publisher","DOI":"10.1111\/j.1439-0507.2011.02025.x"},{"key":"e_1_2_7_25_1","doi-asserted-by":"publisher","DOI":"10.1016\/j.cmi.2016.01.005"},{"key":"e_1_2_7_26_1","doi-asserted-by":"publisher","DOI":"10.1179\/joc.2009.21.3.322"},{"key":"e_1_2_7_27_1","doi-asserted-by":"publisher","DOI":"10.1007\/s10096-003-1035-y"},{"key":"e_1_2_7_28_1","doi-asserted-by":"publisher","DOI":"10.3201\/eid1609.100276"},{"key":"e_1_2_7_29_1","doi-asserted-by":"publisher","DOI":"10.1128\/CMR.18.3.556-569.2005"},{"key":"e_1_2_7_30_1","doi-asserted-by":"publisher","DOI":"10.1080\/13693780701796973"},{"key":"e_1_2_7_31_1","doi-asserted-by":"publisher","DOI":"10.3201\/eid1710.110087"},{"key":"e_1_2_7_32_1","first-page":"43","article-title":"Mucormycosis of the lung, a rare cause for lung cavitations: case report","volume":"18","author":"Mirsadraee M","year":"2006","journal-title":"Iran J Otorhinolaryngol"},{"key":"e_1_2_7_33_1","first-page":"210","article-title":"Orbital mucormycosis in an immunocompetent individual","volume":"4","author":"Badiee P","year":"2012","journal-title":"Iran J Microbiol"},{"key":"e_1_2_7_34_1","first-page":"447","article-title":"Isolated renal mucormycosis after liver transplantation:an unusual case report","volume":"14","author":"Geramizadeh B","year":"2012","journal-title":"Iran Red Crescent Med J"},{"key":"e_1_2_7_35_1","doi-asserted-by":"publisher","DOI":"10.1111\/ped.12182"},{"key":"e_1_2_7_36_1","doi-asserted-by":"publisher","DOI":"10.1111\/j.1469-0691.2006.01604.x"},{"key":"e_1_2_7_37_1","doi-asserted-by":"publisher","DOI":"10.1111\/j.1469-0691.2009.02977.x"},{"key":"e_1_2_7_38_1","doi-asserted-by":"publisher","DOI":"10.1128\/CMR.00056-10"},{"key":"e_1_2_7_39_1","doi-asserted-by":"publisher","DOI":"10.1182\/asheducation-2013.1.423"},{"key":"e_1_2_7_40_1","doi-asserted-by":"publisher","DOI":"10.2217\/fmb.13.78"},{"key":"e_1_2_7_41_1","doi-asserted-by":"publisher","DOI":"10.1016\/0003-4975(94)90243-7"},{"key":"e_1_2_7_42_1","doi-asserted-by":"publisher","DOI":"10.1128\/AAC.50.1.126-133.2006"},{"key":"e_1_2_7_43_1","doi-asserted-by":"publisher","DOI":"10.1097\/00001432-200412000-00003"},{"key":"e_1_2_7_44_1","first-page":"207","article-title":"Mucormycosis in hematologic patients","volume":"89","author":"Pagano L","year":"2004","journal-title":"Haematologica"},{"key":"e_1_2_7_45_1","doi-asserted-by":"publisher","DOI":"10.1046\/j.1365-2141.1997.3983214.x"},{"key":"e_1_2_7_46_1","doi-asserted-by":"publisher","DOI":"10.3109\/13693780903059477"}],"container-title":["Mycoses"],"original-title":[],"language":"en","link":[{"URL":"https:\/\/api.wiley.com\/onlinelibrary\/tdm\/v1\/articles\/10.1111%2Fmyc.12614","content-type":"application\/pdf","content-version":"vor","intended-application":"text-mining"},{"URL":"https:\/\/onlinelibrary.wiley.com\/doi\/pdf\/10.1111\/myc.12614","content-type":"unspecified","content-version":"vor","intended-application":"similarity-checking"}],"deposited":{"date-parts":[[2023,10,1]],"date-time":"2023-10-01T10:12:46Z","timestamp":1696155166000},"score":1,"resource":{"primary":{"URL":"https:\/\/onlinelibrary.wiley.com\/doi\/10.1111\/myc.12614"}},"subtitle":[],"short-title":[],"issued":{"date-parts":[[2017,3,20]]},"references-count":45,"journal-issue":{"issue":"7","published-print":{"date-parts":[[2017,7]]}},"alternative-id":["10.1111\/myc.12614"],"URL":"https:\/\/doi.org\/10.1111\/myc.12614","archive":["Portico"],"relation":{},"ISSN":["0933-7407","1439-0507"],"issn-type":[{"type":"print","value":"0933-7407"},{"type":"electronic","value":"1439-0507"}],"subject":[],"published":{"date-parts":[[2017,3,20]]}}}