{"status":"ok","message-type":"work","message-version":"1.0.0","message":{"indexed":{"date-parts":[[2026,2,10]],"date-time":"2026-02-10T19:39:17Z","timestamp":1770752357900,"version":"3.50.0"},"reference-count":30,"publisher":"Wiley","issue":"4","license":[{"start":{"date-parts":[[2018,1,19]],"date-time":"2018-01-19T00:00:00Z","timestamp":1516320000000},"content-version":"vor","delay-in-days":0,"URL":"http:\/\/onlinelibrary.wiley.com\/termsAndConditions#vor"}],"content-domain":{"domain":[],"crossmark-restriction":false},"short-container-title":["Mycoses"],"published-print":{"date-parts":[[2018,4]]},"abstract":"<jats:title>Summary<\/jats:title><jats:p>Non\u2010<jats:italic>albicans Candida<\/jats:italic> prosthetic joint infection (<jats:styled-content style=\"fixed-case\">PJI<\/jats:styled-content>) is extremely rare. A case of a <jats:italic>Candida glabrata<\/jats:italic> knee <jats:styled-content style=\"fixed-case\">PJI<\/jats:styled-content> is a 68\u2010year\u2010old splenectomised female smoker, suffering from chronic obstructive pulmonary disease (<jats:styled-content style=\"fixed-case\">COPD<\/jats:styled-content>) and alcoholism is reported. The patient presented with a peri\u2010prosthetic fracture, 15\u00a0years after total knee replacement surgery. Cultures of the intraoperative peri\u2010prosthetic tissue and materials yielded <jats:italic>C.\u00a0glabrata,<\/jats:italic> as well as a methicillin\u2010resistant <jats:italic>S.\u00a0epidermitis<\/jats:italic>. The patient was treated with anidulafungin and vancomycin. The knee prosthetic joint was removed and cement\u2010spacer with vancomycin and gentamycin was placed. Additionally, an external fixation was performed. A second stage revision surgery was planned, after completion of the antimicrobial and antifungal treatment. The patient is followed up for 4\u00a0months without signs, symptoms or findings of infection. <jats:styled-content style=\"fixed-case\">PJI <\/jats:styled-content><jats:italic>Candida<\/jats:italic> infections require a high clinical suspicion index. It is of utmost importance to report these cases, since there is no consensus yet of the proper antifungal treatment. Furthermore, a literature review regarding treatment of those cases is provided. First\u2010line treatment with an echinocandin seems most proper, due to their fungicidal properties, their effectiveness against biofilm, as well as their minimal toxicity, making them ideal for long\u2010term use. Further experience is needed, for better understanding the disease's pathogenesis and optimal treatment.<\/jats:p>","DOI":"10.1111\/myc.12736","type":"journal-article","created":{"date-parts":[[2017,12,24]],"date-time":"2017-12-24T09:26:07Z","timestamp":1514107567000},"page":"266-269","source":"Crossref","is-referenced-by-count":22,"title":["<i>Candida glabrata<\/i> prosthetic joint infection, successfully treated with anidulafungin: A case report and review of the literature"],"prefix":"10.1111","volume":"61","author":[{"ORCID":"https:\/\/orcid.org\/0000-0002-1398-9626","authenticated-orcid":false,"given":"Christos","family":"Koutserimpas","sequence":"first","affiliation":[{"name":"Department of Orthopaedics and Traumatology University Hospital of Heraklion  Crete Greece"}],"role":[{"role":"author","vocabulary":"crossref"}]},{"given":"George","family":"Samonis","sequence":"additional","affiliation":[{"name":"Department of Internal Medicine Infectious Diseases Unit University Hospital 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