{"status":"ok","message-type":"work","message-version":"1.0.0","message":{"indexed":{"date-parts":[[2025,11,8]],"date-time":"2025-11-08T13:05:40Z","timestamp":1762607140994,"version":"3.37.3"},"reference-count":26,"publisher":"Wiley","issue":"6","license":[{"start":{"date-parts":[[2018,3,25]],"date-time":"2018-03-25T00:00:00Z","timestamp":1521936000000},"content-version":"vor","delay-in-days":0,"URL":"http:\/\/onlinelibrary.wiley.com\/termsAndConditions#vor"}],"funder":[{"DOI":"10.13039\/501100001411","name":"Indian Council of Medical Research","doi-asserted-by":"publisher","id":[{"id":"10.13039\/501100001411","id-type":"DOI","asserted-by":"publisher"}]}],"content-domain":{"domain":["onlinelibrary.wiley.com"],"crossmark-restriction":true},"short-container-title":["Mycoses"],"published-print":{"date-parts":[[2018,6]]},"abstract":"<jats:title>Summary<\/jats:title><jats:p>Vitamin D deficiency is believed to be a pathogenetic factor in patients with allergic bronchopulmonary aspergillosis (<jats:styled-content style=\"fixed-case\">ABPA<\/jats:styled-content>) and cystic fibrosis. Whether vitamin D deficiency is also prevalent in <jats:styled-content style=\"fixed-case\">ABPA<\/jats:styled-content> complicating asthma, remains unknown. Herein, we evaluated vitamin D levels in asthmatic patients with and without <jats:styled-content style=\"fixed-case\">ABPA<\/jats:styled-content>. In a prospective study, plasma vitamin D (25[<jats:styled-content style=\"fixed-case\">OH<\/jats:styled-content>]D) levels were measured in consecutive subjects with asthma (n\u00a0=\u00a075), <jats:styled-content style=\"fixed-case\">ABPA<\/jats:styled-content> (n\u00a0=\u00a0158) and healthy volunteers (n\u00a0=\u00a050). Vitamin D levels &lt;20\u00a0ng\/<jats:styled-content style=\"fixed-case\">mL<\/jats:styled-content> were considered as vitamin D deficiency. There was no difference in mean (95% <jats:styled-content style=\"fixed-case\">CI<\/jats:styled-content>) vitamin D levels between healthy controls (15.3 [12.7\u201017.9]), asthmatics (19.2 [16.3\u201022.1]) and subjects with <jats:styled-content style=\"fixed-case\">ABPA<\/jats:styled-content> (18.9 [16.9\u201020.8]) (<jats:italic>P<\/jats:italic>\u00a0=\u00a0.22). Vitamin D deficiency was encountered in 70%, 64% and 65% of the healthy controls, asthmatics and <jats:styled-content style=\"fixed-case\">ABPA<\/jats:styled-content> subjects, respectively, and was not different between the groups (<jats:italic>P<\/jats:italic>\u00a0=\u00a0.79). There was no difference in the asthma control, pulmonary function, immunological findings and the severity of bronchiectasis, in patients with <jats:styled-content style=\"fixed-case\">ABPA<\/jats:styled-content>, with and without vitamin D deficiency. Vitamin D deficiency is equally prevalent in asthmatic patients with or without <jats:styled-content style=\"fixed-case\">ABPA<\/jats:styled-content> in the Indian subcontinent, and does not appear to play a major role in the pathogenesis of <jats:styled-content style=\"fixed-case\">ABPA<\/jats:styled-content> complicating asthma.<\/jats:p>","DOI":"10.1111\/myc.12744","type":"journal-article","created":{"date-parts":[[2018,1,4]],"date-time":"2018-01-04T14:00:32Z","timestamp":1515074432000},"page":"344-349","update-policy":"https:\/\/doi.org\/10.1002\/crossmark_policy","source":"Crossref","is-referenced-by-count":11,"title":["Vitamin D levels in asthmatic patients with and without allergic bronchopulmonary aspergillosis"],"prefix":"10.1111","volume":"61","author":[{"ORCID":"https:\/\/orcid.org\/0000-0003-2547-7668","authenticated-orcid":false,"given":"Ritesh","family":"Agarwal","sequence":"first","affiliation":[{"name":"Department of Pulmonary Medicine Postgraduate Institute of Medical Education and Research (PGIMER)  Chandigarh India"}],"role":[{"role":"author","vocabulary":"crossref"}]},{"given":"Inderpaul S.","family":"Sehgal","sequence":"additional","affiliation":[{"name":"Department of Pulmonary Medicine Postgraduate Institute of Medical Education and Research (PGIMER)  Chandigarh India"}],"role":[{"role":"author","vocabulary":"crossref"}]},{"given":"Sahajal","family":"Dhooria","sequence":"additional","affiliation":[{"name":"Department of Pulmonary Medicine Postgraduate Institute of Medical Education and Research (PGIMER)  Chandigarh India"}],"role":[{"role":"author","vocabulary":"crossref"}]},{"given":"Ashutosh N.","family":"Aggarwal","sequence":"additional","affiliation":[{"name":"Department of Pulmonary Medicine Postgraduate Institute of Medical Education and Research (PGIMER)  Chandigarh India"}],"role":[{"role":"author","vocabulary":"crossref"}]},{"given":"Naresh","family":"Sachdeva","sequence":"additional","affiliation":[{"name":"Department of Endocrinology Postgraduate Institute of Medical Education and Research (PGIMER)  Chandigarh India"}],"role":[{"role":"author","vocabulary":"crossref"}]},{"given":"Sanjay K.","family":"Bhadada","sequence":"additional","affiliation":[{"name":"Department of Endocrinology Postgraduate Institute of Medical Education and Research (PGIMER)  Chandigarh India"}],"role":[{"role":"author","vocabulary":"crossref"}]},{"given":"Mandeep","family":"Garg","sequence":"additional","affiliation":[{"name":"Department of Radiodiagnosis and Imaging Postgraduate Institute of Medical Education and Research (PGIMER)  Chandigarh India"}],"role":[{"role":"author","vocabulary":"crossref"}]},{"given":"Digambar","family":"Behera","sequence":"additional","affiliation":[{"name":"Department of Pulmonary Medicine Postgraduate Institute of Medical Education and Research (PGIMER)  Chandigarh India"}],"role":[{"role":"author","vocabulary":"crossref"}]},{"given":"Arunaloke","family":"Chakrabarti","sequence":"additional","affiliation":[{"name":"Department of Medical Microbiology Postgraduate Institute of Medical Education and Research (PGIMER)  Chandigarh India"}],"role":[{"role":"author","vocabulary":"crossref"}]}],"member":"311","published-online":{"date-parts":[[2018,3,25]]},"reference":[{"key":"e_1_2_7_2_1","doi-asserted-by":"publisher","DOI":"10.1111\/cea.12141"},{"key":"e_1_2_7_3_1","doi-asserted-by":"publisher","DOI":"10.3109\/13693786.2012.738312"},{"key":"e_1_2_7_4_1","doi-asserted-by":"publisher","DOI":"10.1371\/journal.pone.0114745"},{"key":"e_1_2_7_5_1","first-page":"936","article-title":"Aspergillus hypersensitivity and allergic bronchopulmonary aspergillosis in patients with bronchial asthma: systematic review and meta\u2010analysis","volume":"13","author":"Agarwal R","year":"2009","journal-title":"Int J Tuberc Lung 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