{"status":"ok","message-type":"work","message-version":"1.0.0","message":{"indexed":{"date-parts":[[2026,10,9]],"date-time":"2026-10-09T21:28:33Z","timestamp":1791581313262,"version":"4.3.4"},"reference-count":26,"publisher":"Wiley","issue":"10","license":[{"start":{"date-parts":[[2018,7,18]],"date-time":"2018-07-18T00:00:00Z","timestamp":1531872000000},"content-version":"vor","delay-in-days":0,"URL":"http:\/\/onlinelibrary.wiley.com\/termsAndConditions#vor"}],"funder":[{"DOI":"10.13039\/100005564","name":"Gilead Sciences","doi-asserted-by":"publisher","id":[{"id":"10.13039\/100005564","id-type":"DOI","asserted-by":"publisher"}]}],"content-domain":{"domain":["onlinelibrary.wiley.com"],"crossmark-restriction":true},"short-container-title":["Mycoses"],"published-print":{"date-parts":[[2018,10]]},"abstract":"<jats:title>Summary<\/jats:title><jats:sec><jats:title>Objectives<\/jats:title><jats:p>To identify the epidemiology and antifungal susceptibilities of <jats:italic>Candida<\/jats:italic> spp. among blood culture isolates to identify the epidemiology and antifungal susceptibilities of <jats:italic>Candida<\/jats:italic> spp. among blood culture isolates in Sweden.<\/jats:p><\/jats:sec><jats:sec><jats:title>Methods<\/jats:title><jats:p>The study was a retrospective, observational nationwide laboratory\u2010based surveillance for fungaemia and fungal meningitis and was conducted from September 2015 to August 2016.<\/jats:p><\/jats:sec><jats:sec><jats:title>Results<\/jats:title><jats:p>In total, 488 <jats:italic>Candida<\/jats:italic> blood culture isolates were obtained from 471 patients (58% males). Compared to our previous study, the incidence of candidaemia has increased from 4.2\/100\u00a0000 (2005\u20102006) to 4.7\/100\u00a0000 population\/year (2015\u20102016). The three most common <jats:italic>Candida<\/jats:italic> spp. isolated from blood cultures were <jats:italic>Candida albicans<\/jats:italic> (54.7%)<jats:italic>, Candida glabrata<\/jats:italic> (19.7%) and species in the <jats:italic>Candida parapsilosis<\/jats:italic> complex (9.4%). <jats:italic>Candida<\/jats:italic> resistance to fluconazole was 2% in <jats:italic>C.\u00a0albicans<\/jats:italic> and between 0% and 100%, in non\u2010<jats:italic>albicans<\/jats:italic> species other than <jats:italic>C.\u00a0glabrata<\/jats:italic> and <jats:italic>C.\u00a0krusei<\/jats:italic>. Resistance to voriconazole was rare, except for <jats:italic>C.\u00a0glabrata<\/jats:italic>,<jats:italic> C.\u00a0krusei<\/jats:italic> and <jats:italic>C.\u00a0tropicalis<\/jats:italic>. Resistance to anidulafungin was 3.8% while no <jats:italic>Candida<\/jats:italic> isolate was resistant to amphotericin B.<\/jats:p><\/jats:sec><jats:sec><jats:title>Conclusions<\/jats:title><jats:p>We report an overall increase in candidaemia but a minor decrease of <jats:italic>C.\u00a0albicans<\/jats:italic> while <jats:italic>C.\u00a0glabrata<\/jats:italic> and <jats:italic>C.\u00a0parapsilosis<\/jats:italic> remain constant over this 10\u2010year period.<\/jats:p><\/jats:sec>","DOI":"10.1111\/myc.12816","type":"journal-article","created":{"date-parts":[[2018,6,19]],"date-time":"2018-06-19T20:13:35Z","timestamp":1529439215000},"page":"777-785","update-policy":"https:\/\/doi.org\/10.1002\/crossmark_policy","source":"Crossref","is-referenced-by-count":27,"title":["Epidemiology of fungaemia in Sweden: A nationwide retrospective observational survey"],"prefix":"10.1111","volume":"61","author":[{"ORCID":"https:\/\/orcid.org\/0000-0001-8259-3556","authenticated-orcid":false,"given":"Lena","family":"Klingspor","sequence":"first","affiliation":[{"name":"Division of Clinical Microbiology Department of Laboratory Medicine Karolinska Institutet  Stockholm Sweden"}],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"M\u00e5ns","family":"Ullberg","sequence":"additional","affiliation":[{"name":"Division of Clinical Microbiology Department of Laboratory Medicine Karolinska Institutet  Stockholm Sweden"},{"name":"Department of Clinical Microbiology Karolinska University Hospital  Stockholm Sweden"}],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Johan","family":"Rydberg","sequence":"additional","affiliation":[{"name":"Division of Laboratory Medicine Department of Clinical Microbiology  Lund Sweden"}],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Nahid","family":"Kondori","sequence":"additional","affiliation":[{"name":"Department of Infectious Diseases Sahlgrenska Academy University of Gothenburg  Gothenburg Sweden"}],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Lena","family":"Serrander","sequence":"additional","affiliation":[{"name":"Department Clinical and Experimental Medicine Link\u00f6ping University  Link\u00f6ping Sweden"}],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Jonas","family":"Swanberg","sequence":"additional","affiliation":[{"name":"Department of Clinical Microbiology Ryhov Hospital  J\u00f6nk\u00f6ping Sweden"}],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Kenneth","family":"Nilsson","sequence":"additional","affiliation":[{"name":"Department of Medical Sciences Section of Clinical Microbiology and Infectious Diseases Uppsala University  Uppsala 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