{"status":"ok","message-type":"work","message-version":"1.0.0","message":{"indexed":{"date-parts":[[2026,8,19]],"date-time":"2026-08-19T19:15:40Z","timestamp":1787166940689,"version":"build-2736575974"},"reference-count":19,"publisher":"Wiley","issue":"11","license":[{"start":{"date-parts":[[2018,8,1]],"date-time":"2018-08-01T00:00:00Z","timestamp":1533081600000},"content-version":"vor","delay-in-days":0,"URL":"http:\/\/onlinelibrary.wiley.com\/termsAndConditions#vor"}],"content-domain":{"domain":["onlinelibrary.wiley.com"],"crossmark-restriction":true},"short-container-title":["Mycoses"],"published-print":{"date-parts":[[2018,11]]},"abstract":"Summary<\/jats:title>\n \n There is a paucity of data regarding mixed mold pulmonary infections (MMPIs) in patients with haematological malignancies with or without haematopoietic stem cell transplantation (HSCT). We retrospectively studied 27 such patients (2005\u20102015) and compared them to patients with invasive pulmonary aspergillosis (IPA) caused by\n Aspergillus fumigatus<\/jats:italic>\n . Factors associated with the diagnosis of MMPIs were significant corticosteroid use [20 (74%) vs 6 (22%),\n P\u00a0<\/jats:italic>\n <\n \u00a0<\/jats:italic>\n 0.001], sputum as the source specimen [13 (48%) vs 3 (11%),\n P\u00a0<\/jats:italic>\n =\n \u00a0<\/jats:italic>\n 0.003], younger age (median age: 58 vs 66\u00a0years,\n P\u00a0<\/jats:italic>\n =\n \u00a0<\/jats:italic>\n 0.006), and male sex [22 (81%) vs 13 (48%),\n P\u00a0<\/jats:italic>\n =\n \u00a0<\/jats:italic>\n 0.01]. Haematological cancers other than acute myeloid leukaemia (AML)\/myelodysplastic syndromes (MDS) were less common in MMPIs than in IPA patients [AML\/MDS: 6 (22%) vs 14 (52%),\n P\u00a0<\/jats:italic>\n =\n \u00a0<\/jats:italic>\n 0.04]. Only significant corticosteroid use [95% CI (2.7\u201042.7),\n P\u00a0<\/jats:italic>\n <\n \u00a0<\/jats:italic>\n 0.001], and sputum as the source specimen [95% (1.6\u201041.6),\n P\u00a0<\/jats:italic>\n =\n \u00a0<\/jats:italic>\n 0.012] were statistically significant as independently associated with increased risk of MMPIs diagnosis in multivariate analysis. Total mortality rate at day 42 postdiagnosis was comparable in both groups.\n <\/jats:p>","DOI":"10.1111\/myc.12830","type":"journal-article","created":{"date-parts":[[2018,7,17]],"date-time":"2018-07-17T07:57:11Z","timestamp":1531814231000},"page":"861-867","update-policy":"https:\/\/doi.org\/10.1002\/crossmark_policy","source":"Crossref","is-referenced-by-count":17,"title":["Mixed mold pulmonary infections in haematological cancer patients in a tertiary care cancer centre"],"prefix":"10.1111","volume":"61","author":[{"ORCID":"https:\/\/orcid.org\/0000-0002-4430-7886","authenticated-orcid":false,"given":"Eleni E.","family":"Magira","sequence":"first","affiliation":[{"name":"Department of Infectious Disease Infection Control and Employee Health The\u00a0University of Texas MD Anderson Cancer Center Houston Texas"},{"name":"First Department of Critical Care Medicine Evangelismos Hospital Medical School of National and Kapodistrian University of Athens Athens Greece"}],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Ying","family":"Jiang","sequence":"additional","affiliation":[{"name":"Department of Infectious Disease Infection Control and Employee Health The\u00a0University of Texas MD Anderson Cancer Center Houston Texas"}],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Minas","family":"Economides","sequence":"additional","affiliation":[{"name":"Department of Infectious Disease Infection Control and Employee Health The\u00a0University of Texas MD Anderson Cancer Center Houston Texas"}],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Jeffrey","family":"Tarrand","sequence":"additional","affiliation":[{"name":"Department of Microbiology The University of Texas MD Anderson Cancer Center Houston Texas"}],"role":[{"vocabulary":"crossref","role":"author"}]},{"ORCID":"https:\/\/orcid.org\/0000-0002-8051-2940","authenticated-orcid":false,"given":"Dimitrios P.","family":"Kontoyiannis","sequence":"additional","affiliation":[{"name":"Department of Infectious Disease Infection Control and Employee Health The\u00a0University of Texas MD Anderson Cancer Center Houston 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