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For this model, the mice were immunosuppressed with a combination of cyclophosphamide at 150\u00a0mg\/kg and hydrocortisone acetate at 250\u00a0mg\/kg. Two groups were formed according to the site of inoculation. Dermatitis group received an intradermal injection of 5\u00a0\u00d7\u00a010<jats:sup>6<\/jats:sup> cell\/mouse at a shaved dorsal region, while the otitis group received the same inoculum in the middle ear. Five animals\/group were euthanised at different times, and the skin and ear were histopathologically analysed. During the first euthanasia, which occurred after inoculation, microscopic examination showed that all mice presented budding yeast\u2010like in a tissue sample. The presence of yeasts decreased over time being undetected on the 17th day (dermatitis group) and the 21st day (otitis group) after inoculation. 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