{"status":"ok","message-type":"work","message-version":"1.0.0","message":{"indexed":{"date-parts":[[2025,10,29]],"date-time":"2025-10-29T19:33:36Z","timestamp":1761766416916,"version":"3.37.3"},"reference-count":90,"publisher":"Wiley","issue":"1","license":[{"start":{"date-parts":[[2018,9,21]],"date-time":"2018-09-21T00:00:00Z","timestamp":1537488000000},"content-version":"vor","delay-in-days":0,"URL":"http:\/\/onlinelibrary.wiley.com\/termsAndConditions#vor"}],"content-domain":{"domain":["onlinelibrary.wiley.com"],"crossmark-restriction":true},"short-container-title":["Mycoses"],"published-print":{"date-parts":[[2019,1]]},"abstract":"<jats:title>Summary<\/jats:title><jats:p>The current number of fungal infections occurring each year in Turkey is unknown. We estimated the burden of serious human fungal diseases based on the population at risk, existing epidemiological data from 1920 to 2017 and modelling previously described by the <jats:styled-content style=\"fixed-case\">LIFE<\/jats:styled-content> program (<jats:ext-link xmlns:xlink=\"http:\/\/www.w3.org\/1999\/xlink\" xlink:href=\"http:\/\/www.LIFE-worldwide.org\">http:\/\/www.LIFE-worldwide.org<\/jats:ext-link>). Among the population of Turkey (80.8 million in 2017), approximately 1\u00a0785\u00a0811 (2.21%) people are estimated to suffer from a serious fungal infection each year. The model used predicts high prevalences of allergic fungal rhinosinusitis episodes (312\u00a0994 cases) (392\/100\u00a0000), of severe asthma with fungal sensitisation (42\u00a0989 cases) (53.20 cases\/100\u00a0000 adults per year), of allergic bronchopulmonary aspergillosis (32\u00a0594 cases) (40.33\/100\u00a0000), of fungal keratitis (26\u00a0671 cases) (33\/100\u00a0000) and of chronic pulmonary aspergillosis (5890 cases) (7.29\/100\u00a0000). The estimated annual incidence for invasive aspergillosis is lower (3911 cases) (4.84\/100\u00a0000 annually). Among about 22.5 million women aged 15\u201050\u00a0years, recurrent vulvovaginal candidiasis is estimated to occur in 1\u00a0350\u00a0371 (3342\/100\u00a0000) females. The burden of three superficial fungal infections was also estimated: tinea pedis (1.79 million), tinea capitis (43\u00a0900) and onychomycosis (1.73 million). Given that the modelling estimates reported in the current study might be substantially under\u2010 or overestimated, formal epidemiological and comprehensive surveillance studies are required to validate or modify these estimates.<\/jats:p>","DOI":"10.1111\/myc.12842","type":"journal-article","created":{"date-parts":[[2018,8,14]],"date-time":"2018-08-14T22:05:11Z","timestamp":1534284311000},"page":"22-31","update-policy":"https:\/\/doi.org\/10.1002\/crossmark_policy","source":"Crossref","is-referenced-by-count":18,"title":["Estimated burden of serious human fungal diseases in Turkey"],"prefix":"10.1111","volume":"62","author":[{"given":"S\u00fcleyha","family":"Hilmio\u011flu\u2010Polat","sequence":"first","affiliation":[{"name":"Department of Microbiology Faculty of Medicine University of Ege  Izmir Turkey"}],"role":[{"role":"author","vocabulary":"crossref"}]},{"ORCID":"https:\/\/orcid.org\/0000-0002-6194-7447","authenticated-orcid":false,"given":"Seyedmojtaba","family":"Seyedmousavi","sequence":"additional","affiliation":[{"name":"Molecular Microbiology Section Laboratory of Clinical Immunology and Microbiology (LCIM) National Institute of Allergy and Infectious Diseases (NIAID) National Institutes of Health (NIH) Bethesda  MD United States of America"},{"name":"Invasive Fungi Research Center Mazandaran University of Medical Sciences  Sari Iran"},{"name":"Center of Expertise in Microbiology Infection Biology and Antimicrobial Pharmacology  Tehran Iran"}],"role":[{"role":"author","vocabulary":"crossref"}]},{"ORCID":"https:\/\/orcid.org\/0000-0002-1174-4182","authenticated-orcid":false,"given":"Macit","family":"Ilkit","sequence":"additional","affiliation":[{"name":"Division of Mycology Department of Microbiology Faculty of Medicine University of \u00c7ukurova  Adana Turkey"}],"role":[{"role":"author","vocabulary":"crossref"}]},{"given":"Mohammad Taghi","family":"Hedayati","sequence":"additional","affiliation":[{"name":"Invasive Fungi Research Center Mazandaran University of Medical Sciences  Sari Iran"},{"name":"Department of Medical Mycology and Parasitology Faculty of Medicine Mazandaran University of Medical Sciences  Sari Iran"}],"role":[{"role":"author","vocabulary":"crossref"}]},{"given":"Ramazan","family":"Inci","sequence":"additional","affiliation":[{"name":"Department of Microbiology Faculty of Medicine University of Ege  Izmir Turkey"}],"role":[{"role":"author","vocabulary":"crossref"}]},{"given":"Emel","family":"Tumbay","sequence":"additional","affiliation":[{"name":"Department of Microbiology Faculty of Medicine University of Ege  Izmir Turkey"}],"role":[{"role":"author","vocabulary":"crossref"}]},{"ORCID":"https:\/\/orcid.org\/0000-0001-5626-2251","authenticated-orcid":false,"given":"David W.","family":"Denning","sequence":"additional","affiliation":[{"name":"The National Aspergillosis Centre Wythenshawe Hospital The University of Manchester, Manchester Academic Health Science Centre  Manchester UK"}],"role":[{"role":"author","vocabulary":"crossref"}]}],"member":"311","published-online":{"date-parts":[[2018,9,21]]},"reference":[{"key":"e_1_2_7_2_1","doi-asserted-by":"publisher","DOI":"10.1101\/cshperspect.a019273"},{"key":"e_1_2_7_3_1","doi-asserted-by":"publisher","DOI":"10.3390\/jof3040057"},{"key":"e_1_2_7_4_1","doi-asserted-by":"publisher","DOI":"10.2471\/BLT.11.089441"},{"key":"e_1_2_7_5_1","doi-asserted-by":"publisher","DOI":"10.1183\/09031936.00054810"},{"key":"e_1_2_7_6_1","doi-asserted-by":"publisher","DOI":"10.1136\/thoraxjnl-2014-206291"},{"key":"e_1_2_7_7_1","doi-asserted-by":"publisher","DOI":"10.1183\/13993003.01062-2016"},{"key":"e_1_2_7_8_1","doi-asserted-by":"publisher","DOI":"10.1016\/S0924-8579(07)72126-X"},{"key":"e_1_2_7_9_1","doi-asserted-by":"publisher","DOI":"10.3906\/sag-1611-90"},{"key":"e_1_2_7_10_1","doi-asserted-by":"publisher","DOI":"10.1111\/myc.12349"},{"key":"e_1_2_7_11_1","doi-asserted-by":"publisher","DOI":"10.4274\/tjh.2014.0277"},{"key":"e_1_2_7_12_1","unstructured":"AkanH UzunO AkovaM et\u00a0al.FUNGOBASE: An epidemiological study to determine the trends in antifungal treatment in Turkey. 9th ECMM\u20101st Trends in Medical Mycology (TIMM).Amsterdam The Netherlands 2017 p. O4.05."},{"key":"e_1_2_7_13_1","doi-asserted-by":"publisher","DOI":"10.1093\/mmy\/myy015"},{"key":"e_1_2_7_14_1","doi-asserted-by":"publisher","DOI":"10.1111\/ijd.13402"},{"key":"e_1_2_7_15_1","doi-asserted-by":"publisher","DOI":"10.2147\/TCRM.S40160"},{"key":"e_1_2_7_16_1","doi-asserted-by":"publisher","DOI":"10.1111\/1469-0691.12000"},{"key":"e_1_2_7_17_1","doi-asserted-by":"publisher","DOI":"10.1016\/j.jinf.2017.07.008"},{"key":"e_1_2_7_18_1","doi-asserted-by":"publisher","DOI":"10.1007\/s10096-017-2922-y"},{"key":"e_1_2_7_19_1","first-page":"489","article-title":"First Pneumocystis carinii infection in Turkey","volume":"21","author":"Unat EK","year":"1955","journal-title":"Turk Tip Cemiy Mecm"},{"key":"e_1_2_7_20_1","doi-asserted-by":"publisher","DOI":"10.1099\/jmm.0.000337"},{"key":"e_1_2_7_21_1","doi-asserted-by":"publisher","DOI":"10.1097\/00002030-200309260-00012"},{"key":"e_1_2_7_22_1","first-page":"1327","article-title":"A case of cryptococcosis of the colon","volume":"22","author":"Unat EK","year":"1959","journal-title":"Tip Fak Mecm"},{"key":"e_1_2_7_23_1","doi-asserted-by":"publisher","DOI":"10.1186\/1471-2458-12-204"},{"key":"e_1_2_7_24_1","doi-asserted-by":"publisher","DOI":"10.3109\/13693786.2012.738312"},{"key":"e_1_2_7_25_1","doi-asserted-by":"publisher","DOI":"10.1016\/S0954-6111(12)70012-4"},{"key":"e_1_2_7_26_1","doi-asserted-by":"publisher","DOI":"10.1016\/S0954-6111(12)70013-6"},{"key":"e_1_2_7_27_1","doi-asserted-by":"publisher","DOI":"10.1016\/S0954-6111(12)70016-1"},{"key":"e_1_2_7_28_1","doi-asserted-by":"publisher","DOI":"10.1016\/S0954-6111(12)70014-8"},{"key":"e_1_2_7_29_1","doi-asserted-by":"publisher","DOI":"10.1186\/s12930-015-0020-9"},{"key":"e_1_2_7_30_1","doi-asserted-by":"publisher","DOI":"10.1111\/j.1469-0691.2009.03015.x"},{"key":"e_1_2_7_31_1","doi-asserted-by":"publisher","DOI":"10.1007\/s00405-013-2449-5"},{"key":"e_1_2_7_32_1","doi-asserted-by":"publisher","DOI":"10.1111\/myc.12314"},{"key":"e_1_2_7_33_1","doi-asserted-by":"publisher","DOI":"10.1016\/j.mycmed.2010.09.002"},{"key":"e_1_2_7_34_1","doi-asserted-by":"publisher","DOI":"10.1016\/S0030-6665(00)80018-3"},{"key":"e_1_2_7_35_1","doi-asserted-by":"publisher","DOI":"10.1016\/S1808-8694(15)31237-4"},{"key":"e_1_2_7_36_1","doi-asserted-by":"publisher","DOI":"10.1016\/j.otohns.2005.03.028"},{"key":"e_1_2_7_37_1","doi-asserted-by":"publisher","DOI":"10.1111\/j.1469-0691.2011.03548.x"},{"key":"e_1_2_7_38_1","doi-asserted-by":"publisher","DOI":"10.1016\/j.ijantimicag.2010.08.010"},{"key":"e_1_2_7_39_1","doi-asserted-by":"publisher","DOI":"10.1002\/cncr.24559"},{"key":"e_1_2_7_40_1","doi-asserted-by":"publisher","DOI":"10.1097\/MCC.0b013e32833e84d2"},{"key":"e_1_2_7_41_1","doi-asserted-by":"publisher","DOI":"10.1111\/j.1469-0691.2010.03360.x"},{"key":"e_1_2_7_42_1","doi-asserted-by":"publisher","DOI":"10.1053\/j.ajkd.2010.12.007"},{"key":"e_1_2_7_43_1","first-page":"255","article-title":"Evaluation of the epidemiological, clinical and laboratory findings in continuous ambulatory peritoneal dialysis related peritonitis attacks","volume":"42","author":"Bulut C","year":"2008","journal-title":"Mikrobiyol Bul"},{"key":"e_1_2_7_44_1","doi-asserted-by":"publisher","DOI":"10.1111\/j.1601-0825.2000.tb00110.x"},{"key":"e_1_2_7_45_1","doi-asserted-by":"publisher","DOI":"10.3109\/00365549009027119"},{"key":"e_1_2_7_46_1","doi-asserted-by":"publisher","DOI":"10.1097\/QAD.0b013e32833a3967"},{"key":"e_1_2_7_47_1","doi-asserted-by":"publisher","DOI":"10.1016\/S0140-6736(07)60917-9"},{"key":"e_1_2_7_48_1","doi-asserted-by":"publisher","DOI":"10.1097\/LGT.0b013e318273e8cf"},{"key":"e_1_2_7_49_1","doi-asserted-by":"publisher","DOI":"10.1186\/1471-2415-14-43"},{"key":"e_1_2_7_50_1","doi-asserted-by":"publisher","DOI":"10.1007\/s10792-007-9069-2"},{"key":"e_1_2_7_51_1","doi-asserted-by":"publisher","DOI":"10.1128\/JCM.38.9.3226-3230.2000"},{"key":"e_1_2_7_52_1","doi-asserted-by":"publisher","DOI":"10.1097\/01.inf.0000151044.21529.3b"},{"key":"e_1_2_7_53_1","doi-asserted-by":"publisher","DOI":"10.5578\/mb.5884"},{"key":"e_1_2_7_54_1","doi-asserted-by":"publisher","DOI":"10.1111\/j.1469-0691.2011.03503.x"},{"key":"e_1_2_7_55_1","doi-asserted-by":"publisher","DOI":"10.1016\/j.ejim.2010.12.014"},{"key":"e_1_2_7_56_1","doi-asserted-by":"publisher","DOI":"10.1007\/s11882-011-0217-4"},{"key":"e_1_2_7_57_1","doi-asserted-by":"publisher","DOI":"10.1183\/09031936.06.00074705"},{"key":"e_1_2_7_58_1","first-page":"52","article-title":"Mold allergy in Adana","volume":"22","author":"Guneser S","year":"1994","journal-title":"Turkey. Allergol Immunopathol (Madr)"},{"key":"e_1_2_7_59_1","doi-asserted-by":"publisher","DOI":"10.1157\/13070603"},{"key":"e_1_2_7_60_1","doi-asserted-by":"crossref","unstructured":"ChakrabartiA KaurH.Allergic Aspergillus Rhinosinusitis. J Fungi.2016;2:32.","DOI":"10.3390\/jof2040032"},{"key":"e_1_2_7_61_1","doi-asserted-by":"publisher","DOI":"10.1016\/j.jcms.2015.08.025"},{"key":"e_1_2_7_62_1","doi-asserted-by":"publisher","DOI":"10.1007\/s00405-007-0529-0"},{"key":"e_1_2_7_63_1","first-page":"153","article-title":"Fungal allergy in chronic rhinosinusitis with or without polyps","volume":"18","author":"Erbek SS","year":"2008","journal-title":"Kulak Burun Bogaz Ihtis Derg"},{"key":"e_1_2_7_64_1","doi-asserted-by":"publisher","DOI":"10.5606\/kbbihtisas.2014.24382"},{"key":"e_1_2_7_65_1","doi-asserted-by":"publisher","DOI":"10.1007\/s00134-013-3134-2"},{"key":"e_1_2_7_66_1","doi-asserted-by":"publisher","DOI":"10.1371\/journal.pone.0153247"},{"key":"e_1_2_7_67_1","doi-asserted-by":"publisher","DOI":"10.1111\/j.1755-6686.2010.00193.x"},{"key":"e_1_2_7_68_1","doi-asserted-by":"publisher","DOI":"10.1080\/00365540601148491"},{"key":"e_1_2_7_69_1","doi-asserted-by":"publisher","DOI":"10.3109\/1040841X.2011.572862"},{"key":"e_1_2_7_70_1","doi-asserted-by":"publisher","DOI":"10.1080\/13693780500225919"},{"key":"e_1_2_7_71_1","doi-asserted-by":"publisher","DOI":"10.1111\/j.1439-0507.2008.01535.x"},{"key":"e_1_2_7_72_1","doi-asserted-by":"publisher","DOI":"10.1111\/1469-0691.12569"},{"key":"e_1_2_7_73_1","first-page":"190","article-title":"A chronic cavitary pulmonary histoplasmosis case from Turkey","volume":"98","author":"Arab HC","year":"1995","journal-title":"J Trop Med Hyg"},{"key":"e_1_2_7_74_1","first-page":"116","article-title":"A rare case in Turkey: pulmonary histoplasmosis","volume":"18","author":"Turhan U","year":"2016","journal-title":"Eurasian J Pulmonol"},{"key":"e_1_2_7_75_1","first-page":"1153","volume":"76","author":"Saglam T","year":"1946","journal-title":"Histoplasmosis. Schweiz Med Wschr"},{"key":"e_1_2_7_76_1","doi-asserted-by":"publisher","DOI":"10.5578\/tt.10207"},{"key":"e_1_2_7_77_1","doi-asserted-by":"publisher","DOI":"10.1128\/JCM.00971-14"},{"key":"e_1_2_7_78_1","doi-asserted-by":"publisher","DOI":"10.1007\/s11046-016-0089-1"},{"key":"e_1_2_7_79_1","article-title":"Estimation of the burden of serious human fungal infections in Malaysia","volume":"4","author":"Velayuthan RD","year":"2018","journal-title":"J Fungi (Basel)"},{"key":"e_1_2_7_80_1","doi-asserted-by":"publisher","DOI":"10.1007\/s10096-017-2929-4"},{"key":"e_1_2_7_81_1","doi-asserted-by":"publisher","DOI":"10.1007\/s10096-017-2919-6"},{"key":"e_1_2_7_82_1","doi-asserted-by":"publisher","DOI":"10.1111\/myc.12393"},{"key":"e_1_2_7_83_1","first-page":"885","article-title":"De la Trichophytie Palmaires","volume":"3","author":"Muhtar C","year":"1892","journal-title":"Ann Derm Syph"},{"key":"e_1_2_7_84_1","doi-asserted-by":"publisher","DOI":"10.1111\/j.1365-4632.2009.04409.x"},{"key":"e_1_2_7_85_1","doi-asserted-by":"publisher","DOI":"10.1055\/s-0028-1135631"},{"key":"e_1_2_7_86_1","first-page":"50","volume":"61","author":"Englaender M. Onychomycosis","year":"1916","journal-title":"Eczema des ongles Gaz Med d'Orient"},{"key":"e_1_2_7_87_1","doi-asserted-by":"publisher","DOI":"10.1111\/j.1365-2133.2004.06112.x"},{"key":"e_1_2_7_88_1","doi-asserted-by":"publisher","DOI":"10.1111\/j.1346-8138.2005.tb00828.x"},{"key":"e_1_2_7_89_1","doi-asserted-by":"crossref","first-page":"125","DOI":"10.1007\/s11046-005-6872-z","article-title":"Non\u2010dermatophytic molds as agents of onychomycosis in Izmir","volume":"160","author":"Hilmioglu\u2010Polat S","year":"2005","journal-title":"Turkey\u2010 a prospective study. Mycopathologia"},{"key":"e_1_2_7_90_1","doi-asserted-by":"publisher","DOI":"10.1111\/j.1346-8138.2009.00663.x"},{"key":"e_1_2_7_91_1","doi-asserted-by":"publisher","DOI":"10.1007\/s11046-015-9939-5"}],"container-title":["Mycoses"],"original-title":[],"language":"en","link":[{"URL":"https:\/\/api.wiley.com\/onlinelibrary\/tdm\/v1\/articles\/10.1111%2Fmyc.12842","content-type":"application\/pdf","content-version":"vor","intended-application":"text-mining"},{"URL":"https:\/\/onlinelibrary.wiley.com\/doi\/pdf\/10.1111\/myc.12842","content-type":"unspecified","content-version":"vor","intended-application":"similarity-checking"}],"deposited":{"date-parts":[[2023,9,15]],"date-time":"2023-09-15T06:12:41Z","timestamp":1694758361000},"score":1,"resource":{"primary":{"URL":"https:\/\/onlinelibrary.wiley.com\/doi\/10.1111\/myc.12842"}},"subtitle":[],"short-title":[],"issued":{"date-parts":[[2018,9,21]]},"references-count":90,"journal-issue":{"issue":"1","published-print":{"date-parts":[[2019,1]]}},"alternative-id":["10.1111\/myc.12842"],"URL":"https:\/\/doi.org\/10.1111\/myc.12842","archive":["Portico"],"relation":{},"ISSN":["0933-7407","1439-0507"],"issn-type":[{"type":"print","value":"0933-7407"},{"type":"electronic","value":"1439-0507"}],"subject":[],"published":{"date-parts":[[2018,9,21]]},"assertion":[{"value":"2018-04-20","order":0,"name":"received","label":"Received","group":{"name":"publication_history","label":"Publication History"}},{"value":"2018-08-09","order":1,"name":"accepted","label":"Accepted","group":{"name":"publication_history","label":"Publication History"}},{"value":"2018-09-21","order":2,"name":"published","label":"Published","group":{"name":"publication_history","label":"Publication History"}}]}}