{"status":"ok","message-type":"work","message-version":"1.0.0","message":{"indexed":{"date-parts":[[2025,10,6]],"date-time":"2025-10-06T06:10:35Z","timestamp":1759731035978,"version":"3.37.3"},"reference-count":13,"publisher":"Wiley","issue":"2","license":[{"start":{"date-parts":[[2018,11,6]],"date-time":"2018-11-06T00:00:00Z","timestamp":1541462400000},"content-version":"vor","delay-in-days":0,"URL":"http:\/\/onlinelibrary.wiley.com\/termsAndConditions#vor"}],"content-domain":{"domain":["onlinelibrary.wiley.com"],"crossmark-restriction":true},"short-container-title":["Mycoses"],"published-print":{"date-parts":[[2019,2]]},"abstract":"<jats:title>Summary<\/jats:title><jats:sec><jats:title>Background<\/jats:title><jats:p><jats:italic>Exserohilum<\/jats:italic> species are environmental moulds that can cause skin infection and sinusitis in both normal and immunosuppressed children. This study reviews paediatric cases of <jats:italic>Exserohilum<\/jats:italic> infection in Queensland, Australia, to identify the spectrum of disease and its clinical course.<\/jats:p><\/jats:sec><jats:sec><jats:title>Methods<\/jats:title><jats:p>All culture\u2010positive samples of <jats:italic>Exserohilum<\/jats:italic> species in children &lt;18\u00a0years of age were identified from the Queensland Health Laboratory database (April 2003\u2010April 2018). Clinical information was recorded from medical records.<\/jats:p><\/jats:sec><jats:sec><jats:title>Results<\/jats:title><jats:p>Eleven children were identified, and all had isolated <jats:italic>Exserohilum rostratum<\/jats:italic>. The mean age was 7.4\u00a0years (range 2.3\u201017.8) and 64% female. Four immunocompetent children (36%) had a skin infection (2\/4), chronic sinusitis (1\/4) or otitis externa (1\/4). Seven children (64%) had an underlying oncological diagnosis with <jats:italic>E.\u00a0rostratum<\/jats:italic> causing local skin infection (2\/7), invasive rhinosinus disease (3\/7) or disseminated infection (2\/7). All oncological patients were empirically started on liposomal amphotericin B with addition, or switch, to posaconazole or voriconazole.<\/jats:p><\/jats:sec><jats:sec><jats:title>Conclusion<\/jats:title><jats:p><jats:italic>Exserohilum rostratum<\/jats:italic> infection of the skin has a favourable course, whereas rhinosinus infection can be rapidly invasive in the immunocompromised child requiring prompt surgical intervention and antifungal therapy. Susceptibility data support empiric use of liposomal amphotericin and\/or posaconazole.<\/jats:p><\/jats:sec>","DOI":"10.1111\/myc.12864","type":"journal-article","created":{"date-parts":[[2018,10,23]],"date-time":"2018-10-23T15:17:02Z","timestamp":1540307822000},"page":"181-185","update-policy":"https:\/\/doi.org\/10.1002\/crossmark_policy","source":"Crossref","is-referenced-by-count":4,"title":["<i>Exserohilum<\/i> infections in Australian Queensland children"],"prefix":"10.1111","volume":"62","author":[{"ORCID":"https:\/\/orcid.org\/0000-0002-1092-5715","authenticated-orcid":false,"given":"Hazel C.","family":"Dobinson","sequence":"first","affiliation":[{"name":"Infection Management and Prevention Service Queensland Children's Hospital  Brisbane Queensland Australia"}],"role":[{"role":"author","vocabulary":"crossref"}]},{"given":"Gregory","family":"Down","sequence":"additional","affiliation":[{"name":"Infection Management and Prevention Service Queensland Children's Hospital  Brisbane Queensland Australia"}],"role":[{"role":"author","vocabulary":"crossref"}]},{"given":"Julia E.","family":"Clark","sequence":"additional","affiliation":[{"name":"Infection Management and Prevention Service Queensland Children's Hospital  Brisbane Queensland Australia"},{"name":"School of Medicine University of Queensland  Brisbane Queensland Australia"}],"role":[{"role":"author","vocabulary":"crossref"}]}],"member":"311","published-online":{"date-parts":[[2018,11,6]]},"reference":[{"key":"e_1_2_7_2_1","doi-asserted-by":"publisher","DOI":"10.1056\/NEJMoa1213978"},{"key":"e_1_2_7_3_1","doi-asserted-by":"publisher","DOI":"10.1093\/mmy\/myv018"},{"key":"e_1_2_7_4_1","doi-asserted-by":"publisher","DOI":"10.1111\/j.1470-9465.2004.00839.x"},{"key":"e_1_2_7_5_1","doi-asserted-by":"publisher","DOI":"10.1128\/AAC.00488-12"},{"key":"e_1_2_7_6_1","first-page":"71","article-title":"Multi\u2010locus phylogeny and taxonomy of Exserohilum","volume":"41","author":"Hern\u00e1ndez\u2010Restrepo M","year":"2018","journal-title":"Blumea"},{"key":"e_1_2_7_7_1","doi-asserted-by":"publisher","DOI":"10.1093\/mmy\/myt030"},{"key":"e_1_2_7_8_1","doi-asserted-by":"publisher","DOI":"10.1097\/ICO.0000000000000774"},{"volume-title":"Descriptions of Medical Fungi","year":"2016","author":"Kidd S","key":"e_1_2_7_9_1"},{"volume-title":"Reference Method for Broth Dilution Antifungal Susceptibility Testing of Filamentous Fungi; Approved Standard","year":"2008","author":"CLSI","key":"e_1_2_7_10_1"},{"key":"e_1_2_7_11_1","doi-asserted-by":"publisher","DOI":"10.1111\/ejh.12910"},{"key":"e_1_2_7_12_1","doi-asserted-by":"publisher","DOI":"10.1016\/S0046-8177(96)90451-7"},{"key":"e_1_2_7_13_1","doi-asserted-by":"publisher","DOI":"10.1111\/1469-0691.12126"},{"key":"e_1_2_7_14_1","doi-asserted-by":"publisher","DOI":"10.1128\/AAC.02006-13"}],"container-title":["Mycoses"],"original-title":[],"language":"en","link":[{"URL":"https:\/\/api.wiley.com\/onlinelibrary\/tdm\/v1\/articles\/10.1111%2Fmyc.12864","content-type":"application\/pdf","content-version":"vor","intended-application":"text-mining"},{"URL":"https:\/\/onlinelibrary.wiley.com\/doi\/pdf\/10.1111\/myc.12864","content-type":"unspecified","content-version":"vor","intended-application":"similarity-checking"}],"deposited":{"date-parts":[[2023,9,14]],"date-time":"2023-09-14T13:36:22Z","timestamp":1694698582000},"score":1,"resource":{"primary":{"URL":"https:\/\/onlinelibrary.wiley.com\/doi\/10.1111\/myc.12864"}},"subtitle":[],"short-title":[],"issued":{"date-parts":[[2018,11,6]]},"references-count":13,"journal-issue":{"issue":"2","published-print":{"date-parts":[[2019,2]]}},"alternative-id":["10.1111\/myc.12864"],"URL":"https:\/\/doi.org\/10.1111\/myc.12864","archive":["Portico"],"relation":{},"ISSN":["0933-7407","1439-0507"],"issn-type":[{"type":"print","value":"0933-7407"},{"type":"electronic","value":"1439-0507"}],"subject":[],"published":{"date-parts":[[2018,11,6]]},"assertion":[{"value":"2018-07-09","order":0,"name":"received","label":"Received","group":{"name":"publication_history","label":"Publication History"}},{"value":"2018-10-17","order":1,"name":"accepted","label":"Accepted","group":{"name":"publication_history","label":"Publication History"}},{"value":"2018-11-06","order":2,"name":"published","label":"Published","group":{"name":"publication_history","label":"Publication History"}}]}}