{"status":"ok","message-type":"work","message-version":"1.0.0","message":{"indexed":{"date-parts":[[2026,9,30]],"date-time":"2026-09-30T12:29:33Z","timestamp":1790771373879,"version":"4.1.0"},"reference-count":26,"publisher":"Wiley","issue":"4","license":[{"start":{"date-parts":[[2019,1,22]],"date-time":"2019-01-22T00:00:00Z","timestamp":1548115200000},"content-version":"vor","delay-in-days":0,"URL":"http:\/\/onlinelibrary.wiley.com\/termsAndConditions#vor"}],"content-domain":{"domain":["onlinelibrary.wiley.com"],"crossmark-restriction":true},"short-container-title":["Mycoses"],"published-print":{"date-parts":[[2019,4]]},"abstract":"<jats:title>Summary<\/jats:title><jats:sec><jats:title>Background<\/jats:title><jats:p>The reliability of diagnostic criteria for invasive fungal diseases (<jats:styled-content style=\"fixed-case\">IFD<\/jats:styled-content>) developed for severely immunocompromised patients is questionable in critically ill adult patients in intensive care units (<jats:styled-content style=\"fixed-case\">ICU<\/jats:styled-content>).<\/jats:p><\/jats:sec><jats:sec><jats:title>Objectives<\/jats:title><jats:p>To develop a standard set of definitions for <jats:styled-content style=\"fixed-case\">IFD<\/jats:styled-content> in critically ill adult patients in <jats:styled-content style=\"fixed-case\">ICU<\/jats:styled-content>.<\/jats:p><\/jats:sec><jats:sec><jats:title>Methods<\/jats:title><jats:p>Based on a systematic literature review, a list of potential definitions to be applied to <jats:styled-content style=\"fixed-case\">ICU<\/jats:styled-content> patients will be developed by the <jats:styled-content style=\"fixed-case\">ESCMID<\/jats:styled-content> Study Group for Infections in Critically Ill Patients (<jats:styled-content style=\"fixed-case\">ESGCIP<\/jats:styled-content>) and the <jats:styled-content style=\"fixed-case\">ESCMID<\/jats:styled-content> Fungal Infection Study Group (<jats:styled-content style=\"fixed-case\">EFISG<\/jats:styled-content>) chairpersons. The proposed definitions will be evaluated by a panel of 30 experts using the <jats:styled-content style=\"fixed-case\">RAND<\/jats:styled-content>\/<jats:styled-content style=\"fixed-case\">UCLA<\/jats:styled-content> appropriateness methods. The panel will rank each of the proposed definitions on a 1\u20109 scale trough a dedicated questionnaire, in two rounds: one remote and one face\u2010to\u2010face. Based on their median rank and the level of agreement across panel members, selected definitions will be organised in a main consensus document and in an executive summary. The executive summary will be made available online for public comments.<\/jats:p><\/jats:sec><jats:sec><jats:title>Conclusions<\/jats:title><jats:p>The present consensus project will seek to provide standard definitions for <jats:styled-content style=\"fixed-case\">IFD<\/jats:styled-content> in critically ill adult patients in ICU, with the ultimate aims of improving their clinical outcome and facilitating the comparison and generalizability of research findings.<\/jats:p><\/jats:sec>","DOI":"10.1111\/myc.12869","type":"journal-article","created":{"date-parts":[[2018,11,14]],"date-time":"2018-11-14T03:04:30Z","timestamp":1542164670000},"page":"310-319","update-policy":"https:\/\/doi.org\/10.1002\/crossmark_policy","source":"Crossref","is-referenced-by-count":63,"title":["Developing definitions for invasive fungal diseases in critically ill adult patients in intensive care units. Protocol of the <scp>FUN<\/scp>gal infections Definitions in <scp>ICU<\/scp> patients (<scp>FUNDICU<\/scp>) project"],"prefix":"10.1111","volume":"62","author":[{"ORCID":"https:\/\/orcid.org\/0000-0002-2004-3724","authenticated-orcid":false,"given":"Matteo","family":"Bassetti","sequence":"first","affiliation":[{"name":"Infectious Diseases Clinic Department of Medicine University of Udine and Santa Maria Misericordia Hospital  Udine Italy"}],"role":[{"vocabulary":"crossref","role":"author"}]},{"ORCID":"https:\/\/orcid.org\/0000-0001-7240-9567","authenticated-orcid":false,"given":"Luigia","family":"Scudeller","sequence":"additional","affiliation":[{"name":"Scientific Direction Fondazione IRCCS Policlinico San Matteo  Pavia Italy"}],"role":[{"vocabulary":"crossref","role":"author"}]},{"ORCID":"https:\/\/orcid.org\/0000-0003-2385-1759","authenticated-orcid":false,"given":"Daniele R.","family":"Giacobbe","sequence":"additional","affiliation":[{"name":"Clinica Malattie Infettive Ospedale 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