{"status":"ok","message-type":"work","message-version":"1.0.0","message":{"indexed":{"date-parts":[[2026,9,22]],"date-time":"2026-09-22T11:51:22Z","timestamp":1790077882994,"version":"4.0.1"},"reference-count":22,"publisher":"Wiley","issue":"4","license":[{"start":{"date-parts":[[2019,2,19]],"date-time":"2019-02-19T00:00:00Z","timestamp":1550534400000},"content-version":"vor","delay-in-days":0,"URL":"http:\/\/onlinelibrary.wiley.com\/termsAndConditions#vor"}],"content-domain":{"domain":["onlinelibrary.wiley.com"],"crossmark-restriction":true},"short-container-title":["Mycoses"],"published-print":{"date-parts":[[2019,4]]},"abstract":"<jats:title>Summary<\/jats:title><jats:sec><jats:title>Background<\/jats:title><jats:p>Limited data exist for epidemiology and outcomes of various agents causing mucormycosis in various clinical settings from developing countries like India.<\/jats:p><\/jats:sec><jats:sec><jats:title>Objectives<\/jats:title><jats:p>To study the epidemiology and outcomes of various agents causing mucormycosis in different clinical settings in a tertiary care hospital from South India.<\/jats:p><\/jats:sec><jats:sec><jats:title>Patients and methods<\/jats:title><jats:p>We reviewed details of 184 consecutive patients with culture\u2010proven mucormycosis with consistent clinical syndrome and supporting features from September 2005 to September 2015.<\/jats:p><\/jats:sec><jats:sec><jats:title>Results<\/jats:title><jats:p>The mean age of patients was 50.42\u00a0years; 70.97% were male. Unlike developed countries, <jats:italic>R\u00a0microsporus<\/jats:italic> (29\/184; 15.7%) and <jats:italic>Apophysomyces elegans<\/jats:italic> (20\/184; 10.8%) also evolved as important pathogens in addition to <jats:italic>R\u00a0arrhizus<\/jats:italic> in our setting. Paranasal sinuses (136\/184; 73.9%) followed by musculoskeletal system (28\/184; 15.2%) were the common areas of involvement. <jats:italic>Apophysomyces elegans<\/jats:italic> typically produced skin and musculoskeletal disease in immune\u2010competent individuals with trauma (12\/20; 60%) and caused significantly lower mortality (<jats:italic>P<\/jats:italic> = 0.03). <jats:italic>R\u00a0microsporus<\/jats:italic> was more common in patients with haematological conditions (25% vs 15.7%) and was less frequently a cause for sinusitis than <jats:italic>R\u00a0arrhizus<\/jats:italic> (27.58% vs 10.9%). The overall mortality was 30.97%. Combination therapy with surgery and antifungals offered the best chance for cure.<\/jats:p><\/jats:sec><jats:sec><jats:title>Conclusions<\/jats:title><jats:p>Agents causing mucormycosis may have unique clinical and epidemiological characteristics.<\/jats:p><\/jats:sec>","DOI":"10.1111\/myc.12897","type":"journal-article","created":{"date-parts":[[2019,1,27]],"date-time":"2019-01-27T09:29:00Z","timestamp":1548581340000},"page":"391-398","update-policy":"https:\/\/doi.org\/10.1002\/crossmark_policy","source":"Crossref","is-referenced-by-count":59,"title":["Mucormycosis\u2014A clinicoepidemiological review of cases over 10\u00a0years"],"prefix":"10.1111","volume":"62","author":[{"ORCID":"https:\/\/orcid.org\/0000-0001-9970-9674","authenticated-orcid":false,"given":"Abi","family":"Manesh","sequence":"first","affiliation":[{"name":"Christian Medical College  Vellore Tamil Nadu 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