{"status":"ok","message-type":"work","message-version":"1.0.0","message":{"indexed":{"date-parts":[[2026,10,7]],"date-time":"2026-10-07T15:36:31Z","timestamp":1791387391408,"version":"4.3.3"},"reference-count":22,"publisher":"Wiley","issue":"5","license":[{"start":{"date-parts":[[2019,3,12]],"date-time":"2019-03-12T00:00:00Z","timestamp":1552348800000},"content-version":"vor","delay-in-days":0,"URL":"http:\/\/creativecommons.org\/licenses\/by-nc\/4.0\/"}],"content-domain":{"domain":["onlinelibrary.wiley.com"],"crossmark-restriction":true},"short-container-title":["Mycoses"],"published-print":{"date-parts":[[2019,5]]},"abstract":"<jats:title>Summary<\/jats:title><jats:sec><jats:title>Background<\/jats:title><jats:p><jats:italic>Candida auris<\/jats:italic> is a globally emerging yeast, causing severe infections in patients with underlying diseases. This yeast is responsible for several outbreaks within healthcare facilities, where it can be found on hospital surfaces and patient care devices. Spread from these fomites may be prevented by improving the decontamination of hospital surfaces. <jats:styled-content style=\"fixed-case\">UV<\/jats:styled-content>\u2010C decontamination may constitute an effective adjunct to routine room cleaning.<\/jats:p><\/jats:sec><jats:sec><jats:title>Objectives<\/jats:title><jats:p>Our aim was to investigate the effect of different <jats:styled-content style=\"fixed-case\">UV<\/jats:styled-content>\u2010C exposure times and distance in killing <jats:italic>C\u00a0auris<\/jats:italic>, using strains from different countries.<\/jats:p><\/jats:sec><jats:sec><jats:title>Methods<\/jats:title><jats:p><jats:italic>Candida auris<\/jats:italic> was seeded on glass slides and exposed to <jats:styled-content style=\"fixed-case\">UV<\/jats:styled-content>\u2010C for 5, 10, 20 and 30\u00a0minutes at 2 and 4\u00a0m.<\/jats:p><\/jats:sec><jats:sec><jats:title>Results<\/jats:title><jats:p>A maximal effect of <jats:italic>C\u00a0auris<\/jats:italic> killing was found after 30\u00a0minutes of <jats:styled-content style=\"fixed-case\">UV<\/jats:styled-content>\u2010C exposure at 2\u00a0m. With half the time or twice the distance, the efficacy strongly diminished to ~10 and ~50 fold, respectively. At suboptimal exposure times and distances, the <jats:italic>C\u00a0auris<\/jats:italic> strains from Japan\/Korea were more sensitive to <jats:styled-content style=\"fixed-case\">UV<\/jats:styled-content>\u2010C killing than <jats:italic>C\u00a0auris<\/jats:italic> strains originating from Venezuela, Spain and India.<\/jats:p><\/jats:sec><jats:sec><jats:title>Conclusions<\/jats:title><jats:p>Altogether, <jats:styled-content style=\"fixed-case\">UV<\/jats:styled-content>\u2010C exposure times and distance are the most critical parameters to kill <jats:italic>C\u00a0auris<\/jats:italic>, while strain variations of <jats:italic>C\u00a0auris<\/jats:italic> also determine <jats:styled-content style=\"fixed-case\">UV<\/jats:styled-content>\u2010C efficacy. Future studies should aim to determine the effect and place of <jats:styled-content style=\"fixed-case\">UV<\/jats:styled-content>\u2010C on surface decontamination in hospital setting.<\/jats:p><\/jats:sec>","DOI":"10.1111\/myc.12903","type":"journal-article","created":{"date-parts":[[2019,2,12]],"date-time":"2019-02-12T18:45:55Z","timestamp":1549997155000},"page":"408-412","update-policy":"https:\/\/doi.org\/10.1002\/crossmark_policy","source":"Crossref","is-referenced-by-count":67,"title":["Killing of <i>Candida auris<\/i> by <scp>UV<\/scp>\u2010C: Importance of exposure time and distance"],"prefix":"10.1111","volume":"62","author":[{"ORCID":"https:\/\/orcid.org\/0000-0001-5841-6461","authenticated-orcid":false,"given":"Theun","family":"de Groot","sequence":"first","affiliation":[{"name":"Department of Medical Microbiology and Infectious Diseases Canisius Wilhelmina Hospital (CWZ)  Nijmegen The Netherlands"}],"role":[{"vocabulary":"crossref","role":"author"}]},{"ORCID":"https:\/\/orcid.org\/0000-0002-2028-7462","authenticated-orcid":false,"given":"Anuradha","family":"Chowdhary","sequence":"additional","affiliation":[{"name":"Department of Medical Mycology Vallabhbhai Patel Chest Institute University of Delhi  Delhi India"}],"role":[{"vocabulary":"crossref","role":"author"}]},{"ORCID":"https:\/\/orcid.org\/0000-0003-3253-6080","authenticated-orcid":false,"given":"Jacques F.","family":"Meis","sequence":"additional","affiliation":[{"name":"Department of Medical Microbiology and Infectious Diseases Canisius Wilhelmina Hospital (CWZ)  Nijmegen The Netherlands"},{"name":"Centre of Expertise in Mycology Radboudumc\/CWZ  Nijmegen The Netherlands"},{"name":"Department of Medical Microbiology Radboudumc  Nijmegen The Netherlands"}],"role":[{"vocabulary":"crossref","role":"author"}]},{"ORCID":"https:\/\/orcid.org\/0000-0002-0689-3773","authenticated-orcid":false,"given":"Andreas","family":"Voss","sequence":"additional","affiliation":[{"name":"Department of Medical Microbiology and Infectious Diseases Canisius Wilhelmina Hospital (CWZ)  Nijmegen The Netherlands"},{"name":"Centre of Expertise in Mycology Radboudumc\/CWZ  Nijmegen The Netherlands"},{"name":"Department of Medical Microbiology Radboudumc  Nijmegen The 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