{"status":"ok","message-type":"work","message-version":"1.0.0","message":{"indexed":{"date-parts":[[2026,10,14]],"date-time":"2026-10-14T12:29:23Z","timestamp":1791980963008,"version":"4.4.0"},"reference-count":39,"publisher":"Wiley","issue":"7","license":[{"start":{"date-parts":[[2019,5,22]],"date-time":"2019-05-22T00:00:00Z","timestamp":1558483200000},"content-version":"vor","delay-in-days":0,"URL":"http:\/\/onlinelibrary.wiley.com\/termsAndConditions#vor"}],"funder":[{"DOI":"10.13039\/100007705","name":"Astellas Pharma Global Development","doi-asserted-by":"publisher","award":["MYCA\u201015L03"],"award-info":[{"award-number":["MYCA\u201015L03"]}],"id":[{"id":"10.13039\/100007705","id-type":"DOI","asserted-by":"publisher"}]},{"DOI":"10.13039\/100000054","name":"National Cancer Institute","doi-asserted-by":"publisher","id":[{"id":"10.13039\/100000054","id-type":"DOI","asserted-by":"publisher"}]}],"content-domain":{"domain":["onlinelibrary.wiley.com"],"crossmark-restriction":true},"short-container-title":["Mycoses"],"published-print":{"date-parts":[[2019,7]]},"abstract":"<jats:title>Summary<\/jats:title><jats:p>Candidaemia is the most common clinical presentation of invasive candidiasis and is a major cause of morbidity and mortality. Candiduria is a predictor for candidaemia; however, patient characteristics that are associated with concurrent candidaemia in the setting of candiduria are unclear. Identifying these characteristics could aid in the early detection of systemic disease. We performed a retrospective cohort analysis of hospitalised patients with candiduria at our institution over a 13\u2010year period. Our evaluation of patient characteristics included demographics, comorbidities, medications, procedures, devices, vital signs and laboratory values. We developed a multivariable logistic model to identify factors associated with candidaemia in patients with candiduria. We identified 4240 patients with candiduria, 263 (6.2%) of whom had candidaemia. Predictors for increased risk of candidaemia with candiduria included hospitalisations\u00a0&gt;\u00a012\u00a0days, central venous catheter, parenteral nutrition, haematological and gynaecological malignancy, and receipt of \u03b2\u2010lactam\/\u03b2\u2010lactamase inhibitors. Vital signs and laboratory values associated with candidaemia included elevated heart rate, temperature and creatinine, along with neutropenia and neutrophilia. Factors that demonstrated a decreased risk of candidaemia included diabetes mellitus, gastrostomy and urinary catheter with antibiotic use. The c\u2010statistic was 0.741 (95% <jats:styled-content style=\"fixed-case\">CI<\/jats:styled-content>, 0.710\u20100.772). We identified a set of clinical characteristics that can predict the presence of candidaemia with candiduria.<\/jats:p>","DOI":"10.1111\/myc.12917","type":"journal-article","created":{"date-parts":[[2019,4,26]],"date-time":"2019-04-26T08:33:37Z","timestamp":1556267617000},"page":"554-561","update-policy":"https:\/\/doi.org\/10.1002\/crossmark_policy","source":"Crossref","is-referenced-by-count":18,"title":["Creation and assessment of a clinical predictive model for candidaemia in patients with candiduria"],"prefix":"10.1111","volume":"62","author":[{"ORCID":"https:\/\/orcid.org\/0000-0003-0295-9576","authenticated-orcid":false,"given":"Katie","family":"Wang","sequence":"first","affiliation":[{"name":"Saint Louis University School of Medicine Saint Louis Missouri"}],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Kevin","family":"Hsueh","sequence":"additional","affiliation":[{"name":"Division of Infectious Diseases Department of Medicine Washington University School of Medicine Saint Louis Missouri"}],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Ryan","family":"Kronen","sequence":"additional","affiliation":[{"name":"Division of Infectious Diseases Department of Medicine Washington University School of Medicine Saint Louis Missouri"},{"name":"Department of Medicine Beth Israel Deaconess Medical Center Boston Massachusetts"}],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Charlotte","family":"Lin","sequence":"additional","affiliation":[{"name":"Division of Infectious Diseases Department of Medicine Washington University School of Medicine Saint Louis Missouri"}],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Ana S.","family":"Salazar","sequence":"additional","affiliation":[{"name":"Division of Infectious Diseases Department of Medicine Washington University School of Medicine Saint Louis Missouri"}],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"William 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