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In recent years, the mortality of <jats:styled-content style=\"fixed-case\">CM<\/jats:styled-content> has remained high in <jats:styled-content style=\"fixed-case\">HIV<\/jats:styled-content>\/<jats:styled-content style=\"fixed-case\">AIDS<\/jats:styled-content> population, with up to 30%, including within developed countries. The treatment usually encompasses controls of <jats:italic>Cryptococcus<\/jats:italic>,<jats:styled-content style=\"fixed-case\"> HIV<\/jats:styled-content>, and increased intracranial pressure. Recent progress on the management of <jats:styled-content style=\"fixed-case\">HIV<\/jats:styled-content>\u2010associated <jats:styled-content style=\"fixed-case\">CM<\/jats:styled-content> mainly centres in optimising induction regimens, looking for appropriate timing of initiating antiretroviral therapy and prevention of symptomatic onset and adverse consequences. This review compared several international guidelines combined with the results from some clinical researches to illustrate the similarities, differences and potential in <jats:styled-content style=\"fixed-case\">CM<\/jats:styled-content> treatment. The present practice is still far from satisfactory, and there remains much to explore due to our limited understanding of the pathogenesis of <jats:styled-content style=\"fixed-case\">HIV<\/jats:styled-content>\u2010associated <jats:styled-content style=\"fixed-case\">CM<\/jats:styled-content>. Thus, screening and monitoring should be strengthened, and better therapies in line with the actual situation of each country should be discovered.<\/jats:p>","DOI":"10.1111\/myc.12977","type":"journal-article","created":{"date-parts":[[2019,7,31]],"date-time":"2019-07-31T20:57:44Z","timestamp":1564606664000},"page":"874-882","update-policy":"https:\/\/doi.org\/10.1002\/crossmark_policy","source":"Crossref","is-referenced-by-count":4,"title":["Management of human immunodeficiency virus\u2013associated cryptococcal meningitis: Current status and future directions"],"prefix":"10.1111","volume":"62","author":[{"ORCID":"https:\/\/orcid.org\/0000-0002-6087-4960","authenticated-orcid":false,"given":"Xueyun","family":"Wu","sequence":"first","affiliation":[{"name":"Department of Infection and Immunity Shanghai Public Health Clinical Center Fudan University Shanghai China"}],"role":[{"role":"author","vocabulary":"crossref"}]},{"given":"Yinzhong","family":"Shen","sequence":"additional","affiliation":[{"name":"Department of Infection and Immunity Shanghai Public Health Clinical Center Fudan University Shanghai China"}],"role":[{"role":"author","vocabulary":"crossref"}]}],"member":"311","published-online":{"date-parts":[[2019,8,18]]},"reference":[{"key":"e_1_2_13_2_1","unstructured":"Guidelines for the diagnosis prevention and management of cryptococcal disease in HIV\u2010infected adults adolescents and children.World Health Organization.http:\/\/apps.who.int\/iris\/bitstream\/handle\/10665\/260399\/9789241550277-eng.pdf;jsessionxml:id=0C0706E99DE971B25C5D2E38582F700C?sequence=1%. 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