{"status":"ok","message-type":"work","message-version":"1.0.0","message":{"indexed":{"date-parts":[[2026,1,15]],"date-time":"2026-01-15T11:56:15Z","timestamp":1768478175754,"version":"3.49.0"},"reference-count":32,"publisher":"Wiley","issue":"11","license":[{"start":{"date-parts":[[2019,8,25]],"date-time":"2019-08-25T00:00:00Z","timestamp":1566691200000},"content-version":"vor","delay-in-days":0,"URL":"http:\/\/onlinelibrary.wiley.com\/termsAndConditions#vor"}],"content-domain":{"domain":["onlinelibrary.wiley.com"],"crossmark-restriction":true},"short-container-title":["Mycoses"],"published-print":{"date-parts":[[2019,11]]},"abstract":"<jats:title>Summary<\/jats:title><jats:p>The aim of this study was to estimate the annual burden of fungal infections in Sweden using data mainly from 2016. Data on specific populations were obtained from Swedish national data registries. Annual incidence and prevalence of fungal disease was calculated based on epidemiological studies. Data on infections due to <jats:italic>Cryptococcus<\/jats:italic> sp., Mucorales, <jats:italic>Histoplasma capsulatum<\/jats:italic>,<jats:italic> Coccidioides immitis<\/jats:italic> and <jats:italic>Pneumocystis jirovecii<\/jats:italic> were retrieved from Karolinska University Laboratory and covers only 25% of Swedish population. In 2016, the population of Sweden was 9\u00a0995\u00a0153 (49.8% female). The overall burden of fungal infections was 1\u00a0713\u00a0385 (17\u00a0142\/100\u00a0000). Superficial fungal infections affect 1\u00a0429\u00a0307 people (1429\/100\u00a0000) based on Global Burden of Disease 14.3% prevalence. Total serious fungal infection burden was 284 174 (2843\/100\u00a0000) in 2016. Recurrent <jats:italic>Candida<\/jats:italic> vulvovaginitis is common; assuming a 6% prevalence in women. Prevalence of allergic bronchopulmonary aspergillosis and severe asthma with fungal sensitisation were estimated to be 20\u00a0095 and 26\u00a0387, respectively. Similarly, chronic pulmonary aspergillosis was estimated to affect 490 patients after tuberculosis, sarcoidosis and other conditions. Candidemia incidence was estimated to be 500 in 2016 (4.7\/100\u00a0000) and invasive aspergillosis 295 (3.0\/100\u00a0000). In Stockholm area, Mucorales were reported in three patients in 2015, while <jats:italic>Cryptococcus<\/jats:italic> spp. were reported in two patients. In 2016, there were 297 patients PCR positive for <jats:italic>P\u00a0jirovecii<\/jats:italic>. The present study shows that the overall burden of fungal infections in Sweden is high and affects 17% of the population. The morbidity, mortality and the healthcare\u2010related costs due to fungal infections warrant further studies.<\/jats:p>","DOI":"10.1111\/myc.12981","type":"journal-article","created":{"date-parts":[[2019,8,3]],"date-time":"2019-08-03T07:38:08Z","timestamp":1564817888000},"page":"1043-1048","update-policy":"https:\/\/doi.org\/10.1002\/crossmark_policy","source":"Crossref","is-referenced-by-count":12,"title":["Estimated burden of fungal infections in Sweden"],"prefix":"10.1111","volume":"62","author":[{"given":"Volkan","family":"\u00d6zenci","sequence":"first","affiliation":[{"name":"Division of Clinical Microbiology Department of Laboratory Medicine Karolinska Institutet Stockholm Sweden"},{"name":"Department of Clinical Microbiology Karolinska University Hospital Stockholm 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