{"status":"ok","message-type":"work","message-version":"1.0.0","message":{"indexed":{"date-parts":[[2026,1,8]],"date-time":"2026-01-08T20:46:30Z","timestamp":1767905190904,"version":"3.49.0"},"reference-count":13,"publisher":"Wiley","issue":"11","license":[{"start":{"date-parts":[[2019,9,9]],"date-time":"2019-09-09T00:00:00Z","timestamp":1567987200000},"content-version":"vor","delay-in-days":0,"URL":"http:\/\/onlinelibrary.wiley.com\/termsAndConditions#vor"}],"content-domain":{"domain":["onlinelibrary.wiley.com"],"crossmark-restriction":true},"short-container-title":["Mycoses"],"published-print":{"date-parts":[[2019,11]]},"abstract":"<jats:title>Summary<\/jats:title><jats:p>Candidemia can complicate major surgical procedures. However, literature data are scanty on this topic. In this study, we evaluated the epidemiology, clinical and microbiologic characteristics and outcome of candidemia in adult patients with recent surgery hospitalised in a single University Hospital in Central Italy from 2010 to 2016. Of the 304 episodes of candidemia, 160 (53%) occurred in surgical patients (<jats:styled-content style=\"fixed-case\">SP<\/jats:styled-content>s) while the remaining 144 (47%) in patients without history of recent surgery (non\u2010<jats:styled-content style=\"fixed-case\">SP<\/jats:styled-content>s). Although either underlying chronic comorbidities (ie haematological malignancies, neurological and gastrointestinal diseases) or acute complications (ie pneumonia and septic shock) were less likely to occur in <jats:styled-content style=\"fixed-case\">SP<\/jats:styled-content>s than in non\u2010<jats:styled-content style=\"fixed-case\">SP<\/jats:styled-content>s, 30\u2010day mortality did not differ between groups being 38% and 42%, respectively. The specific risk factors significantly more common in <jats:styled-content style=\"fixed-case\">SP<\/jats:styled-content>s who died within 30\u00a0days were as follows: male gender, older age, being hospitalised in <jats:styled-content style=\"fixed-case\">ICU<\/jats:styled-content> rather than in other wards, having a higher Charlson's score, undergoing previous invasive procedures, haemodialysis, the presence of pneumonia, septic shock, acute kidney failure and the type of surgery. In particular, either gastrointestinal or cardiovascular surgeries were characterised by the highest mortality rates. Multivariate analysis showed that the occurrence of septic shock (<jats:styled-content style=\"fixed-case\">HR<\/jats:styled-content> 10.3131 [<jats:styled-content style=\"fixed-case\">CI<\/jats:styled-content>95% 1.176\u201090.466; <jats:italic>P<\/jats:italic>\u00a0=\u00a0.035] and <jats:styled-content style=\"fixed-case\">ICU<\/jats:styled-content> stay (<jats:styled-content style=\"fixed-case\">HR<\/jats:styled-content> 2.016 [<jats:styled-content style=\"fixed-case\">CI<\/jats:styled-content>95% 1.178\u20103.448; <jats:italic>P<\/jats:italic>\u00a0=\u00a0.011] was independently associated with higher mortality in <jats:styled-content style=\"fixed-case\">SP<\/jats:styled-content>s. Overall, these data show that candidemia in <jats:styled-content style=\"fixed-case\">SP<\/jats:styled-content>s is characterised by significant mortality and distinctive features.<\/jats:p>","DOI":"10.1111\/myc.12988","type":"journal-article","created":{"date-parts":[[2019,8,17]],"date-time":"2019-08-17T14:58:22Z","timestamp":1566053902000},"page":"1056-1063","update-policy":"https:\/\/doi.org\/10.1002\/crossmark_policy","source":"Crossref","is-referenced-by-count":12,"title":["Characterisation of candidemia in patients with recent surgery: A 7\u2010year experience"],"prefix":"10.1111","volume":"62","author":[{"given":"Elena","family":"Orsetti","sequence":"first","affiliation":[{"name":"Malattie infettive Ospedale A. Murri Fermo Italy"}],"role":[{"role":"author","vocabulary":"crossref"}]},{"given":"Lucia","family":"Brescini","sequence":"additional","affiliation":[{"name":"Clinica Malattie Infettive Dipartimento di Scienze Biomediche e Sanit\u00e0 Pubblica Universit\u00e0 Politecnica delle Marche Azienda Ospedaliera Universitaria Ospedali Riuniti Umberto I\u2010Lancisi\u2010Salesi Ancona Italy"}],"role":[{"role":"author","vocabulary":"crossref"}]},{"given":"Sara","family":"Mazzanti","sequence":"additional","affiliation":[{"name":"Clinica Malattie Infettive Dipartimento di Scienze Biomediche e Sanit\u00e0 Pubblica Universit\u00e0 Politecnica delle Marche Azienda Ospedaliera Universitaria Ospedali Riuniti Umberto I\u2010Lancisi\u2010Salesi Ancona Italy"}],"role":[{"role":"author","vocabulary":"crossref"}]},{"given":"Francesca","family":"Trave","sequence":"additional","affiliation":[{"name":"Clinica Malattie Infettive Dipartimento di Scienze Biomediche e Sanit\u00e0 Pubblica Universit\u00e0 Politecnica delle Marche Azienda Ospedaliera Universitaria Ospedali Riuniti Umberto I\u2010Lancisi\u2010Salesi Ancona Italy"}],"role":[{"role":"author","vocabulary":"crossref"}]},{"given":"Gianluca","family":"Morroni","sequence":"additional","affiliation":[{"name":"Clinica Malattie Infettive Dipartimento di Scienze Biomediche e Sanit\u00e0 Pubblica Universit\u00e0 Politecnica delle Marche Azienda Ospedaliera Universitaria Ospedali Riuniti Umberto I\u2010Lancisi\u2010Salesi Ancona Italy"}],"role":[{"role":"author","vocabulary":"crossref"}]},{"given":"Annamaria","family":"Masucci","sequence":"additional","affiliation":[{"name":"Laboratorio di Microbiologia Azienda Ospedaliera Universitaria Ospedali Riuniti Umberto I\u2010Lancisi\u2010Salesi Ancona Italy"}],"role":[{"role":"author","vocabulary":"crossref"}]},{"ORCID":"https:\/\/orcid.org\/0000-0003-1098-902X","authenticated-orcid":false,"given":"Francesco","family":"Barchiesi","sequence":"additional","affiliation":[{"name":"Clinica Malattie Infettive 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