{"status":"ok","message-type":"work","message-version":"1.0.0","message":{"indexed":{"date-parts":[[2026,9,27]],"date-time":"2026-09-27T13:30:03Z","timestamp":1790515803877,"version":"4.1.0"},"reference-count":33,"publisher":"Wiley","issue":"1","license":[{"start":{"date-parts":[[2019,11,3]],"date-time":"2019-11-03T00:00:00Z","timestamp":1572739200000},"content-version":"vor","delay-in-days":0,"URL":"http:\/\/onlinelibrary.wiley.com\/termsAndConditions#vor"}],"funder":[{"DOI":"10.13039\/501100004160","name":"Mazandaran University of Medical Sciences","doi-asserted-by":"publisher","award":["2819"],"award-info":[{"award-number":["2819"]}],"id":[{"id":"10.13039\/501100004160","id-type":"DOI","asserted-by":"publisher"}]}],"content-domain":{"domain":["onlinelibrary.wiley.com"],"crossmark-restriction":true},"short-container-title":["Mycoses"],"published-print":{"date-parts":[[2020,1]]},"abstract":"<jats:title>Summary<\/jats:title><jats:p>The molecular epidemiology and antifungal susceptibility of <jats:italic>Aspergillus nidulans<\/jats:italic> species complex has not been well studied. To evaluate the genetic diversity and antifungal susceptibility patterns of clinical and environmental isolates of <jats:italic>A.\u00a0nidulans<\/jats:italic> complex. Sixty clinical and environmental isolates of <jats:italic>Aspergillus<\/jats:italic> section <jats:italic>Nidulantes<\/jats:italic> were collected from five countries (Iran, The Netherlands, Spain, Portugal and Greece). The species were molecularly identified by sequencing of \u03b2\u2010tubulin gene. The genetic diversity of <jats:italic>A\u00a0nidulans<\/jats:italic> complex isolates (n\u00a0=\u00a054) was determined with a microsatellite genotyping assay. Antifungal susceptibility profile was determined using EUCAST method. The isolates were classified as <jats:italic>A\u00a0nidulans<\/jats:italic> (46.7%), <jats:italic>A\u00a0spinulosporus<\/jats:italic> (26.6%), <jats:italic>A\u00a0quadrilineatus<\/jats:italic> (10%), <jats:italic>A\u00a0pachycristatus<\/jats:italic> (3.3%), <jats:italic>A\u00a0rugulosus<\/jats:italic> (3.3%), <jats:italic>A\u00a0unguis<\/jats:italic> (5%), <jats:italic>A\u00a0creber<\/jats:italic>, (1.7%), <jats:italic>A\u00a0olivicola<\/jats:italic> (1.7%) and <jats:italic>A\u00a0sydowii<\/jats:italic> (1.7%). Thirty\u2010four sequence types (STs) were identified among the 54 <jats:italic>A\u00a0nidulans<\/jats:italic> complex isolates. A high level of genetic diversity was found among <jats:italic>A\u00a0nidulans<\/jats:italic> sensu stricto strains but low diversity was found among <jats:italic>A\u00a0spinulosporus<\/jats:italic> strains. Amphotericin B showed high MICs to all species. The most active azole was posaconazole (GM\u00a0=\u00a00.64\u00a0mg\/L), while itraconazole showed the highest MICs among azoles (GM\u00a0=\u00a02.95\u00a0mg\/L). <jats:italic>A\u00a0spinulosporus<\/jats:italic> showed higher MICs than <jats:italic>A\u00a0nidulans<\/jats:italic> sensu stricto for all antifungals except for micafungin and anidulafungin. Interspecies variations may result in differences in antifungal susceptibility patterns and challenge antifungal therapy in infections caused by <jats:italic>A\u00a0nidulans<\/jats:italic>. Differences in the distribution of STs or persistence of multiple STs might be related to the sources of isolation and niche specialisation.<\/jats:p>","DOI":"10.1111\/myc.13019","type":"journal-article","created":{"date-parts":[[2019,10,14]],"date-time":"2019-10-14T11:12:06Z","timestamp":1571051526000},"page":"78-88","update-policy":"https:\/\/doi.org\/10.1002\/crossmark_policy","source":"Crossref","is-referenced-by-count":27,"title":["Genetic diversity and antifungal susceptibility patterns of <i>Aspergillus nidulans<\/i> complex obtained from clinical and environmental sources"],"prefix":"10.1111","volume":"63","author":[{"given":"Mahin","family":"Tavakoli","sequence":"first","affiliation":[{"name":"Student Research Committee Invasive Fungi Research Center Mazandaran University of Medical Sciences Sari Iran"}],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Olga","family":"Rivero\u2010Menendez","sequence":"additional","affiliation":[{"name":"Medical Mycology Reference 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