{"status":"ok","message-type":"work","message-version":"1.0.0","message":{"indexed":{"date-parts":[[2026,7,10]],"date-time":"2026-07-10T06:28:51Z","timestamp":1783664931663,"version":"3.55.0"},"reference-count":18,"publisher":"Wiley","issue":"5","license":[{"start":{"date-parts":[[2020,3,4]],"date-time":"2020-03-04T00:00:00Z","timestamp":1583280000000},"content-version":"vor","delay-in-days":0,"URL":"http:\/\/onlinelibrary.wiley.com\/termsAndConditions#vor"}],"content-domain":{"domain":["onlinelibrary.wiley.com"],"crossmark-restriction":true},"short-container-title":["Mycoses"],"published-print":{"date-parts":[[2020,5]]},"abstract":"<jats:title>Summary<\/jats:title><jats:p>Invasive pulmonary aspergillosis (IPA) optimal duration of antifungal treatment is not known. In a joint effort, four international scientific societies\/groups performed a survey to capture current practices in European haematology centres regarding management of IPA. We conducted a cross\u2010sectional internet\u2010based questionnaire survey in 2017 to assess practices in sixteen European countries concerning IPA management in haematology patients including tools to evaluate treatment response, duration and discontinuation. The following four groups\/societies were involved in the project: European Society of Clinical Microbiology and Infectious Diseases (ESCMID) Fungal Infection Study Group (EFISG), Infectious Diseases Working Party\u2010European Society for Blood and Bone Marrow Transplantation (IDWP\u2010EBMT), European Organisation for Research and Treatment\u2010Infectious Disease group (EORTC\u2010IDG) and Sorveglianza Epidemiologica Infezioni nelle Emopatie (SEIFEM). A total of 112 physicians from 14\/16 countries answered the survey. Galactomannan antigen was available in serum and bronchoalveolar lavage in most centres (106\/112 [95%] and 97\/112 [87%], respectively), quantitative <jats:italic>Aspergillus<\/jats:italic> PCR in 27\/112 (24%) centres, \u03b2\u2010D\u2010glucan in 24\/112 (21%) and positron emission tomography in 50\/112 (45%). Treatment duration differed between haematological malignancies, with a median duration of 6\u00a0weeks [IQR 3\u201012] for patients with AML, 11 [4\u201012] for patients with allogenic stem cell transplantation and GvHD and 6 [3\u201012] for patients with lymphoproliferative disease. Treatment duration significantly differed according to country. Essential IPA biomarkers are not available in all European countries, and treatment duration is highly variable according to country. It will be important to provide guidelines to help with IPA treatment cessation with algorithms according to biomarker availability.<\/jats:p>","DOI":"10.1111\/myc.13056","type":"journal-article","created":{"date-parts":[[2020,2,3]],"date-time":"2020-02-03T09:56:18Z","timestamp":1580723778000},"page":"420-429","update-policy":"https:\/\/doi.org\/10.1002\/crossmark_policy","source":"Crossref","is-referenced-by-count":23,"title":["Invasive pulmonary aspergillosis treatment duration in haematology patients in Europe: An EFISG, IDWP\u2010EBMT, EORTC\u2010IDG and SEIFEM survey"],"prefix":"10.1111","volume":"63","author":[{"ORCID":"https:\/\/orcid.org\/0000-0003-3800-4683","authenticated-orcid":false,"given":"Fanny","family":"Lanternier","sequence":"first","affiliation":[{"name":"Service de Maladies Infectieuses et Tropicales H\u00f4pital Necker\u2010Enfants Malades Assistance Publique\u2010H\u00f4pitaux de Paris (APHP) Universit\u00e9 de Paris Paris France"},{"name":"Institut Pasteur CNRS Unit\u00e9 de Mycologie Mol\u00e9culaire Centre National de R\u00e9f\u00e9rence Mycoses Invasives et Antifongiques UMR2000 Paris France"}],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Danila","family":"Seidel","sequence":"additional","affiliation":[{"name":"Cologne Excellence Cluster on Cellular Stress Responses in Aging\u2010Associated Diseases (CECAD) University of Cologne Cologne Germany"},{"name":"Department I of Internal Medicine Faculty of Medicine European Excellence Center for Medical Mycology (ECMM) University of Cologne Cologne Germany"}],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Livio","family":"Pagano","sequence":"additional","affiliation":[{"name":"Policlinico Universitario Agostino Gemelli \u2013IRCCS Roma Italy"},{"name":"Universit\u00e0 Cattolica del Sacro Cuore Roma Italy"},{"name":"SEIFEM (Sorveglianza Epidemiologica Infezioni nelle EMopatie) Roma Italy"}],"role":[{"vocabulary":"crossref","role":"author"}]},{"ORCID":"https:\/\/orcid.org\/0000-0002-3158-119X","authenticated-orcid":false,"given":"Jan","family":"Styczynski","sequence":"additional","affiliation":[{"name":"Department of Pediatric Hematology and Oncology Collegium Medicum Nicolaus Copernicus University Bydgoszcz Poland"}],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Malgorzata","family":"Mikulska","sequence":"additional","affiliation":[{"name":"Division of infectious diseases Ospedale Polyclinico San Martino University of Genoa (DISSAL) Genova Italy"}],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Celine","family":"Pulcini","sequence":"additional","affiliation":[{"name":"Infectious Diseases Department APEMAC \u00e9quipe MICS CHRU\u2010Nancy Universit\u00e9 de Lorraine Nancy France"}],"role":[{"vocabulary":"crossref","role":"author"}]},{"ORCID":"https:\/\/orcid.org\/0000-0003-4257-5980","authenticated-orcid":false,"given":"Johan","family":"Maertens","sequence":"additional","affiliation":[{"name":"Department of Microbiology, Immunology, and Transplantation KU Leuven Leuven Belgium"},{"name":"Department of Haematology University Hospitals Leuven Leuven Belgium"}],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Patricia","family":"Munoz","sequence":"additional","affiliation":[{"name":"Department of Clinical Microbiology and Infectious Diseases Hospital General Universitario Gregorio Mara\u00f1\u00f3n Department of Medicine School of Medicine Universidad Complutense de Madrid Madrid Spain"}],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Carol","family":"Garcia\u2010Vidal","sequence":"additional","affiliation":[{"name":"Department of Infectious Diseases Hospital Clinic IDIBAPS (Institut d\u2019Investigacions Biom\u00e8diques Agust 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Institute of Health Dr. Ricardo Jorge Lisbon Portugal"}],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Cristina","family":"Verissimo","sequence":"additional","affiliation":[{"name":"Reference Unit for Parasitic and Fungal Infections Infectious Diseases Department National Institute of Health Dr. Ricardo Jorge Lisbon Portugal"}],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Peter","family":"Gaustad","sequence":"additional","affiliation":[{"name":"Department of Microbiology Oslo University Hospital Oslo Norway"}],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Nikolay","family":"Klimko","sequence":"additional","affiliation":[{"name":"Department of Clinical Mycology, Allergy and Immunology North\u2010Western State Medical University St Petersburg Russian"}],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Sevtap","family":"Arikan\u2010Akdagli","sequence":"additional","affiliation":[{"name":"Department of Infectious Diseases and Clinical Microbiology Hacettepe University Medical School Ankara Turkey"}],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Valentina","family":"Arsic","sequence":"additional","affiliation":[{"name":"National Reference Laboratory for Medical Mycology University of Belgrade Belgrade Serbia"}],"role":[{"vocabulary":"crossref","role":"author"}]},{"ORCID":"https:\/\/orcid.org\/0000-0002-0132-2277","authenticated-orcid":false,"given":"Aleksandra","family":"Barac","sequence":"additional","affiliation":[{"name":"Clinic for Infectious and Tropic Diseases Faculty of Medicine Clinical Centre of Serbia University of Belgrade Belgrade Serbia"}],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Anna","family":"Skiada","sequence":"additional","affiliation":[{"name":"National and Kapodistrian University of Athens Athens 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