{"status":"ok","message-type":"work","message-version":"1.0.0","message":{"indexed":{"date-parts":[[2026,6,18]],"date-time":"2026-06-18T06:18:07Z","timestamp":1781763487215,"version":"3.54.5"},"reference-count":49,"publisher":"Wiley","issue":"4","license":[{"start":{"date-parts":[[2020,12,20]],"date-time":"2020-12-20T00:00:00Z","timestamp":1608422400000},"content-version":"vor","delay-in-days":0,"URL":"http:\/\/onlinelibrary.wiley.com\/termsAndConditions#vor"}],"content-domain":{"domain":["onlinelibrary.wiley.com"],"crossmark-restriction":true},"short-container-title":["Mycoses"],"published-print":{"date-parts":[[2021,4]]},"abstract":"<jats:title>Abstract<\/jats:title><jats:p>Dermatophytosis is a common superficial mycotic infection affecting individual's quality of life worldwide. The present study aimed to perform species\u2010level identification and evaluate the antifungal susceptibility patterns of dermatophytes isolated in Shiraz, Iran. This cross\u2010sectional study was conducted on clinical samples collected during 2017\u20102019 from 307 patients suspected of having dermatophytosis.\u00a0The isolates were identified by direct microscopy, culture and internal transcribed spacer ribosomal DNA sequencing, and their antifungal susceptibility patterns were determined by the microdilution method. Among 307 patients, dermatophytosis was diagnosed by microscopy in 190 (61.8%) subjects and confirmed in 130 (42.3%) cases by both microscopy and culture. It was found out tinea pedis was the most common clinical manifestation, and <jats:italic>Trichophyton mentagrophytes<\/jats:italic> was the most prevalent species (28.4%), followed by <jats:italic>T<\/jats:italic> <jats:italic>tonsurans<\/jats:italic> (23.8%), <jats:italic>Microsporum canis<\/jats:italic> (11.5%), <jats:italic>T<\/jats:italic> <jats:italic>interdigitale<\/jats:italic> (10%), <jats:italic>T<\/jats:italic> <jats:italic>verrucosum<\/jats:italic> (6.9%), <jats:italic>T<\/jats:italic> <jats:italic>rubrum<\/jats:italic> (6.9%), <jats:italic>T<\/jats:italic> <jats:italic>benhamiae<\/jats:italic> (4.6%), <jats:italic>T<\/jats:italic> <jats:italic>violaceum<\/jats:italic> (3%), <jats:italic>T<\/jats:italic> <jats:italic>simii<\/jats:italic> (3%), <jats:italic>Epidermophyton floccosum<\/jats:italic> (0.7%) and <jats:italic>M<\/jats:italic> <jats:italic>ferrugineum<\/jats:italic> (0.7%). Moreover, it was revealed that luliconazole with a geometric mean (GM) minimum inhibitory concentration (MIC) of 0.03\u00a0\u03bcg\u00a0ml<jats:sup>\u20101<\/jats:sup> was the most effective agent against all tested isolates. Regardless of species, 30% of isolates responded to high MICs of griseofulvin (MIC<jats:sub>90<\/jats:sub>\u00a0&gt;\u00a02\u00a0\u03bcg\u00a0ml<jats:sup>\u20101<\/jats:sup>). The increasing prevalence of nonindigenous species of <jats:italic>T<\/jats:italic> <jats:italic>simii<\/jats:italic>, <jats:italic>T<\/jats:italic> <jats:italic>benhamiae<\/jats:italic> and <jats:italic>M<\/jats:italic> <jats:italic>ferrugineum<\/jats:italic> in Shiraz, Iran, was a notable finding. In addition, infections due to zoophilic species showed an increasing trend. These epidemiological data, along with antifungal susceptibility patterns, may\u00a0have implications for clinical\u00a0decision\u2010making\u00a0and successful treatment.<\/jats:p>","DOI":"10.1111\/myc.13226","type":"journal-article","created":{"date-parts":[[2020,12,10]],"date-time":"2020-12-10T07:12:58Z","timestamp":1607584378000},"page":"385-393","update-policy":"https:\/\/doi.org\/10.1002\/crossmark_policy","source":"Crossref","is-referenced-by-count":21,"title":["Molecular identification and antifungal susceptibility among clinical isolates of dermatophytes in Shiraz, Iran (2017\u20102019)"],"prefix":"10.1111","volume":"64","author":[{"ORCID":"https:\/\/orcid.org\/0000-0003-0314-7502","authenticated-orcid":false,"given":"Zahra","family":"Zareshahrabadi","sequence":"first","affiliation":[{"name":"Department of Medical Mycology and Parasitology School of Medicine Shiraz University of Medical Sciences Shiraz 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