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Inclusion of diverse groups in onychomycosis clinical trials subjects is necessary to generalise efficacy data.<\/jats:p><\/jats:sec><jats:sec><jats:title>Objectives<\/jats:title><jats:p>We aimed to systematically review race and ethnicity reporting and representation, as well as, treatment outcomes in onychomycosis clinical trials.<\/jats:p><\/jats:sec><jats:sec><jats:title>Methods<\/jats:title><jats:p>A PubMed search for onychomycosis clinical trials was performed in August 2020. Primary clinical trial data were included and post hoc analyses were excluded. Categorical variables were compared using chi\u2010squared and Fisher's exact tests. Statistical significance was set at<jats:italic>p<\/jats:italic>\u00a0&lt;\u00a0.05. Photos in articles were categorised by Fitzpatrick skin type.<\/jats:p><\/jats:sec><jats:sec><jats:title>Results<\/jats:title><jats:p>Only 32\/182 (17.5%) trials reported on race and\/or ethnicity and only one trial compared treatment efficacy in different subgroups. Darker skin colours were infrequently depicted in articles. Topical treatment, location with \u22651 US\u2010based site, industry funding type and publication date after 2000 were significantly associated with reporting of racial\/ethnic data (<jats:italic>p<\/jats:italic>\u00a0&lt;\u00a0.05 for all comparisons).<\/jats:p><\/jats:sec><jats:sec><jats:title>Limitations<\/jats:title><jats:p>Demographics on excluded subjects and methods of recruitment were not available. Assigning Fitzpatrick skin type is inherently subjective.<\/jats:p><\/jats:sec><jats:sec><jats:title>Conclusions<\/jats:title><jats:p>This study highlights a need for consistent reporting of races and ethnicities of onychomycosis clinical trial participants with subgroup analyses of treatment efficacies.<\/jats:p><\/jats:sec>","DOI":"10.1111\/myc.13262","type":"journal-article","created":{"date-parts":[[2021,3,3]],"date-time":"2021-03-03T04:00:49Z","timestamp":1614744049000},"page":"954-966","update-policy":"https:\/\/doi.org\/10.1002\/crossmark_policy","source":"Crossref","is-referenced-by-count":11,"title":["Race reporting and representation in onychomycosis clinical trials: A systematic review"],"prefix":"10.1111","volume":"64","author":[{"ORCID":"https:\/\/orcid.org\/0000-0002-8974-9151","authenticated-orcid":false,"given":"Michelle J.","family":"Chang","sequence":"first","affiliation":[{"name":"Drexel University College of Medicine Philadelphia PA USA"}],"role":[{"role":"author","vocabulary":"crossref"}]},{"given":"Yuqing","family":"Qiu","sequence":"additional","affiliation":[{"name":"Department of Population Health Sciences Weill Cornell Medicine New York NY USA"},{"name":"Department of Dermatology Weill Cornell Medicine New York NY USA"}],"role":[{"role":"author","vocabulary":"crossref"}]},{"ORCID":"https:\/\/orcid.org\/0000-0001-5913-9304","authenticated-orcid":false,"given":"Shari R.","family":"Lipner","sequence":"additional","affiliation":[{"name":"Department of Dermatology Weill Cornell Medicine New York NY USA"}],"role":[{"role":"author","vocabulary":"crossref"}]}],"member":"311","published-online":{"date-parts":[[2021,3,13]]},"reference":[{"key":"e_1_2_8_2_1","doi-asserted-by":"publisher","DOI":"10.1080\/09546634.2019.1679337"},{"key":"e_1_2_8_3_1","doi-asserted-by":"publisher","DOI":"10.1016\/j.jaad.2018.03.062"},{"key":"e_1_2_8_4_1","doi-asserted-by":"publisher","DOI":"10.1016\/j.jaad.2018.05.1260"},{"key":"e_1_2_8_5_1","unstructured":"AlanisJ.Minority participation in clinical trials: an elusive goal. 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