{"status":"ok","message-type":"work","message-version":"1.0.0","message":{"indexed":{"date-parts":[[2026,7,21]],"date-time":"2026-07-21T18:32:31Z","timestamp":1784658751654,"version":"3.55.0"},"reference-count":59,"publisher":"Wiley","issue":"10","license":[{"start":{"date-parts":[[2021,7,24]],"date-time":"2021-07-24T00:00:00Z","timestamp":1627084800000},"content-version":"vor","delay-in-days":0,"URL":"http:\/\/onlinelibrary.wiley.com\/termsAndConditions#vor"}],"content-domain":{"domain":["onlinelibrary.wiley.com"],"crossmark-restriction":true},"short-container-title":["Mycoses"],"published-print":{"date-parts":[[2021,10]]},"abstract":"<jats:title>Abstract<\/jats:title><jats:sec><jats:title>Importance<\/jats:title><jats:p>Coronavirus disease (COVID\u201019) causes an immunosuppressed state and increases risk of secondary infections like mucormycosis. We evaluated clinical features, predisposing factors, diagnosis and outcomes for mucormycosis among patients with COVID\u201019 infection.<\/jats:p><\/jats:sec><jats:sec><jats:title>Methods<\/jats:title><jats:p>This prospective, observational, multi\u2010centre study included 47 consecutive patients with mucormycosis, diagnosed during their course of COVID\u201019 illness, between January 3 and March 27, 2021. Data regarding demography, underlying medical conditions, COVID\u201019 illness and treatment were collected. Clinical presentations of mucormycosis, imaging and biochemical characteristics and outcome were recorded.<\/jats:p><\/jats:sec><jats:sec><jats:title>Results<\/jats:title><jats:p>Of the 2567 COVID\u201019 patients admitted to 3 tertiary centres, 47 (1.8%) were diagnosed with mucormycosis. Mean age was 55\u00a0\u00b1\u00a012.8years, and majority suffered from diabetes mellitus (<jats:italic>n<\/jats:italic>\u00a0=\u00a036, 76.6%). Most were not COVID\u201019 vaccinated (<jats:italic>n<\/jats:italic>\u00a0=\u00a031, 66.0%) and majority (<jats:italic>n<\/jats:italic>\u00a0=\u00a043, 91.5%) had developed moderate\u2010to\u2010severe pneumonia, while 20 (42.6%) required invasive ventilation. All patients had received corticosteroids and broad\u2010spectrum antibiotics while most (<jats:italic>n<\/jats:italic>\u00a0=\u00a037, 78.7%) received at least one anti\u2010viral medication. Mean time elapsed from COVID\u201019 diagnosis to mucormycosis was 12.1\u00a0\u00b1\u00a04.6days. Eleven (23.4%) subjects succumbed to their disease, mostly (<jats:italic>n<\/jats:italic>\u00a0=\u00a08, 72.7%) within 7\u00a0days of diagnosis. Among the patients who died, 10 (90.9%) had pre\u2010existing diabetes mellitus, only 2 (18.2%) had received just one vaccine dose and all developed moderate\u2010to\u2010severe pneumonia, requiring oxygen supplementation and mechanical ventilation.<\/jats:p><\/jats:sec><jats:sec><jats:title>Conclusions<\/jats:title><jats:p>Mucormycosis can occur among COVID\u201019 patients, especially with poor glycaemic control, widespread and injudicious use of corticosteroids and broad\u2010spectrum antibiotics, and invasive ventilation. Owing to the high mortality, high index of suspicion is required to ensure timely diagnosis and appropriate treatment in high\u2010risk populations.<\/jats:p><\/jats:sec>","DOI":"10.1111\/myc.13353","type":"journal-article","created":{"date-parts":[[2021,7,13]],"date-time":"2021-07-13T19:03:57Z","timestamp":1626203037000},"page":"1253-1260","update-policy":"https:\/\/doi.org\/10.1002\/crossmark_policy","source":"Crossref","is-referenced-by-count":146,"title":["Mucormycosis and COVID\u201019: An epidemic within a pandemic in India"],"prefix":"10.1111","volume":"64","author":[{"given":"Lav","family":"Selarka","sequence":"first","affiliation":[{"name":"Zydus Hospital Ahmedabad Gujarat India"}],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Suktara","family":"Sharma","sequence":"additional","affiliation":[{"name":"Department of ENT GCS Medical College Ahmedabad 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