{"status":"ok","message-type":"work","message-version":"1.0.0","message":{"indexed":{"date-parts":[[2026,6,13]],"date-time":"2026-06-13T13:53:56Z","timestamp":1781358836495,"version":"3.54.1"},"reference-count":20,"publisher":"Wiley","issue":"1","license":[{"start":{"date-parts":[[2021,10,28]],"date-time":"2021-10-28T00:00:00Z","timestamp":1635379200000},"content-version":"vor","delay-in-days":0,"URL":"http:\/\/onlinelibrary.wiley.com\/termsAndConditions#vor"}],"content-domain":{"domain":["onlinelibrary.wiley.com"],"crossmark-restriction":true},"short-container-title":["Mycoses"],"published-print":{"date-parts":[[2022,1]]},"abstract":"<jats:title>Abstract<\/jats:title><jats:sec><jats:title>Background<\/jats:title><jats:p>COVID\u201019\u2013associated mucormycosis (CAM) has emerged as a challenging complication as the current pandemic has increased the population requiring treatment with corticosteroids. CAM has caused a massive outbreak in India, reported to be causing cases in Iran, Egypt and The Netherlands.<\/jats:p><\/jats:sec><jats:sec><jats:title>Objectives<\/jats:title><jats:p>To describe CAM cases occurring in a single centre in Western Mexico.<\/jats:p><\/jats:sec><jats:sec><jats:title>Methods<\/jats:title><jats:p>Our group carried out a retrospective study from May 2020 to May 2021 to identify CAM cases in patients with previous COVID\u201019 diagnosis.<\/jats:p><\/jats:sec><jats:sec><jats:title>Results<\/jats:title><jats:p>Six CAM cases occurred in a single centre in Western Mexico during the study period, most of them with diabetes (<jats:italic>n<\/jats:italic>\u00a0=\u00a05\/6) and all received corticosteroid therapy even when only three had severe COVID\u201019. After analysing local COVID\u201019 burden, it was estimated that in this region, CAM was 300 times more frequent among COVID individuals than the estimates for general population.<\/jats:p><\/jats:sec><jats:sec><jats:title>Conclusion<\/jats:title><jats:p>Similar to large reports in India and other countries, CAM cases reported in this study were diagnosed in individuals with diabetes, hyperglycaemic status and with history of previous use of corticosteroids. Identifying these individuals at risk can help the early identification of CAM. In addition, strict glycaemic control and avoidance of unnecessary corticosteroid in non\u2010severe COVID\u201019 cases could help in preventing this complicated fungal infection.<\/jats:p><\/jats:sec>","DOI":"10.1111\/myc.13383","type":"journal-article","created":{"date-parts":[[2021,10,21]],"date-time":"2021-10-21T16:29:45Z","timestamp":1634833785000},"page":"65-70","update-policy":"https:\/\/doi.org\/10.1002\/crossmark_policy","source":"Crossref","is-referenced-by-count":18,"title":["COVID\u201019\u2013associated mucormycosis, diabetes and steroid therapy: Experience in a single centre in Western Mexico"],"prefix":"10.1111","volume":"65","author":[{"given":"Salvador","family":"Guzm\u00e1n\u2010Castro","sequence":"first","affiliation":[{"name":"Hospital General \u201cDr. Miguel Silva\u201d SSM Morelia Mexico"}],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Luis David","family":"Chora\u2010Hernandez","sequence":"additional","affiliation":[{"name":"Hospital General \u201cDr. Miguel Silva\u201d SSM Morelia Mexico"}],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Gersain","family":"Trujillo\u2010Alonso","sequence":"additional","affiliation":[{"name":"Hospital General \u201cDr. Miguel Silva\u201d SSM Morelia Mexico"}],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Ivan","family":"Calvo\u2010Villalobos","sequence":"additional","affiliation":[{"name":"Hospital General \u201cDr. Miguel Silva\u201d SSM Morelia Mexico"}],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Antonio","family":"Sanchez\u2010Rangel","sequence":"additional","affiliation":[{"name":"Hospital General \u201cDr. Miguel Silva\u201d SSM Morelia Mexico"}],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Edgar","family":"Ferrer\u2010Alpuin","sequence":"additional","affiliation":[{"name":"Hospital General \u201cDr. Miguel Silva\u201d SSM Morelia Mexico"}],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Miguel","family":"Ruiz\u2010Jimenez","sequence":"additional","affiliation":[{"name":"Microbiology Gerency Asesores Diagn\u00f3stico Cl\u00ednico Puebla Mexico"}],"role":[{"vocabulary":"crossref","role":"author"}]},{"ORCID":"https:\/\/orcid.org\/0000-0003-4012-1045","authenticated-orcid":false,"given":"Dora E.","family":"Corzo\u2010Leon","sequence":"additional","affiliation":[{"name":"The Institute of Medical Sciences University of Aberdeen Aberdeen UK"}],"role":[{"vocabulary":"crossref","role":"author"}]}],"member":"311","published-online":{"date-parts":[[2021,10,28]]},"reference":[{"key":"e_1_2_8_2_1","unstructured":"World Health Organization.WHO Coronavirus (COVID\u201019) dashboard. Accessed September 29 2021.https:\/\/covid19.who.int\/"},{"key":"e_1_2_8_3_1","volume-title":"Coronavirus Disease 2019 (COVID\u201019) Treatment Guidelines","author":"COVID\u201019 Treatment Guidelines Panel"},{"key":"e_1_2_8_4_1","doi-asserted-by":"publisher","DOI":"10.1056\/NEJMoa2021436"},{"key":"e_1_2_8_5_1","doi-asserted-by":"publisher","DOI":"10.1016\/j.puhe.2021.05.028"},{"key":"e_1_2_8_6_1","doi-asserted-by":"publisher","DOI":"10.1111\/myc.13335"},{"key":"e_1_2_8_7_1","doi-asserted-by":"publisher","DOI":"10.4103\/ijo.IJO_1565_21"},{"key":"e_1_2_8_8_1","doi-asserted-by":"publisher","DOI":"10.1111\/myc.13351"},{"issue":"23","key":"e_1_2_8_9_1","article-title":"Case series of four secondary mucormycosis infections in COVID\u201019 patients, the Netherlands","volume":"26","author":"Buil JB","year":"2021","journal-title":"Eurosurveillance"},{"key":"e_1_2_8_10_1","article-title":"Spike in rhino\u2010orbital\u2010cerebral mucormycosis cases presenting to a tertiary care center during the COVID\u201019 pandemic","volume":"8","author":"Fouad YA","year":"2021","journal-title":"Front Med (Lausanne)"},{"key":"e_1_2_8_11_1","doi-asserted-by":"publisher","DOI":"10.1016\/j.ijid.2021.08.037"},{"key":"e_1_2_8_12_1","unstructured":"Secretaria de salud Michoacan.Centro Estatal de Operaciones COVID\u201019 SSM. 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