{"status":"ok","message-type":"work","message-version":"1.0.0","message":{"indexed":{"date-parts":[[2026,8,18]],"date-time":"2026-08-18T01:16:17Z","timestamp":1787015777628,"version":"build-2736575974"},"reference-count":10,"publisher":"Wiley","issue":"2","license":[{"start":{"date-parts":[[2021,12,3]],"date-time":"2021-12-03T00:00:00Z","timestamp":1638489600000},"content-version":"vor","delay-in-days":0,"URL":"http:\/\/creativecommons.org\/licenses\/by\/4.0\/"}],"content-domain":{"domain":["onlinelibrary.wiley.com"],"crossmark-restriction":true},"short-container-title":["Mycoses"],"published-print":{"date-parts":[[2022,2]]},"abstract":"Abstract<\/jats:title>\n \n Background<\/jats:title>\n \n Since the first report of\n Candida auris<\/jats:italic>\n in 2016, the Colombian Instituto Nacional de Salud (INS) has implemented a national surveillance of the emerging multidrug\u2010resistant fungus.\n <\/jats:p>\n <\/jats:sec>\n \n Objectives<\/jats:title>\n This report summarises the findings of this laboratory\u2010based surveillance from March 2016 to December 2020.<\/jats:p>\n <\/jats:sec>\n \n Results<\/jats:title>\n \n A total of 1720\n C. auris<\/jats:italic>\n cases were identified, including 393 (23%) colonisation cases and 1327 (77%) clinical cases. Cases were reported in 20 of 32 (62%) departments of Colombia and involved hospitals from 33 cities. The median age of patients was 34\u00a0years; 317 (18%) cases were children under 16\u00a0years, 54% were male. The peak number of cases was observed in 2019 (\n n<\/jats:italic>\n \u00a0=\u00a0541). In 2020, 379 (94%) of 404 cases reported were clinical cases, including 225 bloodstream infections (BSI) and 154 non\u2010BSI. Among the 404 cases reported in 2020, severe COVID\u201019 was reported in 122 (30%). Antifungal susceptibility was tested in 379 isolates. Using CDC tentative breakpoints for resistance, 35% of isolates were fluconazole resistant, 33% were amphotericin B resistant, and 0.3% isolates were anidulafungin resistant, 12% were multidrug resistant, and no pan\u2010resistant isolates were identified.\n <\/jats:p>\n <\/jats:sec>\n \n Conclusion<\/jats:title>\n For five years of surveillance, we observed an increase in the number and geographic spread of clinical cases and an increase in fluconazole resistance. These observations emphasise the need for improved measures to mitigate spread.<\/jats:p>\n <\/jats:sec>","DOI":"10.1111\/myc.13390","type":"journal-article","created":{"date-parts":[[2021,11,3]],"date-time":"2021-11-03T13:47:18Z","timestamp":1635947238000},"page":"222-225","update-policy":"https:\/\/doi.org\/10.1002\/crossmark_policy","source":"Crossref","is-referenced-by-count":28,"title":["Laboratory\u2010based surveillance of\n Candida auris<\/i>\n in Colombia, 2016\u20132020"],"prefix":"10.1111","volume":"65","author":[{"ORCID":"https:\/\/orcid.org\/0000-0003-3029-118X","authenticated-orcid":false,"given":"Patricia","family":"Escand\u00f3n","sequence":"first","affiliation":[{"name":"Grupo de Microbiolog\u00eda Instituto Nacional de Salud Bogot\u00e1 Colombia"}],"role":[{"vocabulary":"crossref","role":"author"}]},{"ORCID":"https:\/\/orcid.org\/0000-0001-8749-9809","authenticated-orcid":false,"given":"Diego H.","family":"C\u00e1ceres","sequence":"additional","affiliation":[{"name":"Centers for Disease Control and Prevention (CDC) Atlanta Georgia USA"},{"name":"Center of Expertise in Mycology Radboudumc\/CWZ Nijmegen The Netherlands"}],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Diana","family":"Lizarazo","sequence":"additional","affiliation":[{"name":"Grupo de Microbiolog\u00eda Instituto Nacional de Salud Bogot\u00e1 Colombia"}],"role":[{"vocabulary":"crossref","role":"author"}]},{"ORCID":"https:\/\/orcid.org\/0000-0002-4383-5994","authenticated-orcid":false,"given":"Shawn R.","family":"Lockhart","sequence":"additional","affiliation":[{"name":"Centers for Disease Control and Prevention (CDC) Atlanta Georgia USA"}],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Meghan","family":"Lyman","sequence":"additional","affiliation":[{"name":"Centers for Disease Control and Prevention (CDC) Atlanta Georgia USA"}],"role":[{"vocabulary":"crossref","role":"author"}]},{"ORCID":"https:\/\/orcid.org\/0000-0001-7596-8292","authenticated-orcid":false,"given":"Carolina","family":"Duarte","sequence":"additional","affiliation":[{"name":"Grupo de Microbiolog\u00eda Instituto Nacional de Salud Bogot\u00e1 Colombia"}],"role":[{"vocabulary":"crossref","role":"author"}]}],"member":"311","published-online":{"date-parts":[[2021,12,3]]},"reference":[{"key":"e_1_2_8_2_1","unstructured":"INS.Alerta de C. auris \u2010 Instituto Nacional de Salud;2016. Disponible en:\u00a0http:\/\/www.ins.gov.co\/tramites\u2010y\u2010servicios\/examenes\u2010de\u2010inter%C3%A9s\u2010en\u2010salud\u2010publica\/Microbiologa\/Alerta%20de%20C.%20auris.pdf"},{"key":"e_1_2_8_3_1","doi-asserted-by":"publisher","DOI":"10.3390\/jof5040111"},{"key":"e_1_2_8_4_1","doi-asserted-by":"publisher","DOI":"10.1093\/mmy\/myy054"},{"key":"e_1_2_8_5_1","unstructured":"CLSI.M60 Performance Standards for Antifungal Susceptibility Testing of Yeasts 1st Edition 2017. Available from:https:\/\/clsi.org\/"},{"key":"e_1_2_8_6_1","unstructured":"(CDC) CfDCaP.Recommendations for Identification of\u00a0Candida auris;2018. Available from:https:\/\/www.cdc.gov\/fungal\/candida\u2010auris\/recommendations.html"},{"key":"e_1_2_8_7_1","unstructured":"CSTE.Standardized Case Definition for Candida auris clinical and colonization\/screening cases and National Notification of C. auris case clinical;2018. Available from:https:\/\/cdn.ymaws.com\/www.cste.org\/resource\/resmgr\/ps\/2018ps\/18\u2010ID\u201005_Dec2018_Update.pdf"},{"issue":"1","key":"e_1_2_8_8_1","first-page":"15","article-title":"Molecular epidemiology of Candida auris in Colombia reveals a highly\u2010related, country\u2010wide colonization with regional patterns in Amphotericin B resistance","volume":"68","author":"Escandon P","year":"2019","journal-title":"Clin Infect Dis"},{"key":"e_1_2_8_9_1","doi-asserted-by":"publisher","DOI":"10.1080\/14787210.2020.1750368"},{"key":"e_1_2_8_10_1","doi-asserted-by":"publisher","DOI":"10.1016\/j.jinf.2016.07.008"},{"key":"e_1_2_8_11_1","doi-asserted-by":"publisher","DOI":"10.1111\/myc.12709"}],"container-title":["Mycoses"],"original-title":[],"language":"en","link":[{"URL":"https:\/\/onlinelibrary.wiley.com\/doi\/pdf\/10.1111\/myc.13390","content-type":"application\/pdf","content-version":"vor","intended-application":"text-mining"},{"URL":"https:\/\/onlinelibrary.wiley.com\/doi\/full-xml\/10.1111\/myc.13390","content-type":"application\/xml","content-version":"vor","intended-application":"text-mining"},{"URL":"https:\/\/onlinelibrary.wiley.com\/doi\/pdf\/10.1111\/myc.13390","content-type":"unspecified","content-version":"vor","intended-application":"similarity-checking"}],"deposited":{"date-parts":[[2023,8,25]],"date-time":"2023-08-25T19:53:59Z","timestamp":1692993239000},"score":1,"resource":{"primary":{"URL":"https:\/\/onlinelibrary.wiley.com\/doi\/10.1111\/myc.13390"}},"subtitle":[],"short-title":[],"issued":{"date-parts":[[2021,12,3]]},"references-count":10,"journal-issue":{"issue":"2","published-print":{"date-parts":[[2022,2]]}},"alternative-id":["10.1111\/myc.13390"],"URL":"https:\/\/doi.org\/10.1111\/myc.13390","archive":["Portico"],"relation":{},"ISSN":["0933-7407","1439-0507"],"issn-type":[{"value":"0933-7407","type":"print"},{"value":"1439-0507","type":"electronic"}],"subject":[],"published":{"date-parts":[[2021,12,3]]},"assertion":[{"value":"2021-09-08","order":0,"name":"received","label":"Received","group":{"name":"publication_history","label":"Publication History"}},{"value":"2021-10-22","order":1,"name":"accepted","label":"Accepted","group":{"name":"publication_history","label":"Publication History"}},{"value":"2021-12-03","order":2,"name":"published","label":"Published","group":{"name":"publication_history","label":"Publication History"}}]}}