{"status":"ok","message-type":"work","message-version":"1.0.0","message":{"indexed":{"date-parts":[[2026,9,29]],"date-time":"2026-09-29T06:05:58Z","timestamp":1790661958510,"version":"4.1.0"},"reference-count":14,"publisher":"Wiley","issue":"3","license":[{"start":{"date-parts":[[2022,1,3]],"date-time":"2022-01-03T00:00:00Z","timestamp":1641168000000},"content-version":"vor","delay-in-days":0,"URL":"http:\/\/onlinelibrary.wiley.com\/termsAndConditions#vor"}],"content-domain":{"domain":["onlinelibrary.wiley.com"],"crossmark-restriction":true},"short-container-title":["Mycoses"],"published-print":{"date-parts":[[2022,3]]},"abstract":"<jats:title>Abstract<\/jats:title><jats:sec><jats:title>Background<\/jats:title><jats:p>Paracoccidioidomycosis, caused by fungi of the <jats:italic>Paracoccidioides<\/jats:italic> genus, is one of the most important endemic mycoses in Brazil. The disease is not of mandatory reporting in the country; however, some Brazilian states, such as Paran\u00e1, have included it on their local lists of public health\u2010reportable diseases.<\/jats:p><\/jats:sec><jats:sec><jats:title>Objective<\/jats:title><jats:p>Describe the epidemiology of the positive paracoccidioidomycosis cases in the state of Paran\u00e1 based on analysis of reporting forms and mortality data.<\/jats:p><\/jats:sec><jats:sec><jats:title>Subjects and methods<\/jats:title><jats:p>Data of positive cases of state residents 2007\u20132020 were obtained from public health databases and frequency, incidence, geographic distribution, mortality and trends were analysed. Mortality of the disease was also compared to other mycoses such as cryptococcosis, aspergillosis, histoplasmosis, candidiasis and sporotrichosis.<\/jats:p><\/jats:sec><jats:sec><jats:title>Results<\/jats:title><jats:p>670 patients were positive for the disease. The cumulative and average annual incidence was, respectively, 6.4 and 0.46\u00a0cases\/100,000 inhabitants. The new cases of paracoccidioidomycosis were reported mainly by specialised health units, including tertiary centres, and 285\u00a0days was the mean from the beginning of the symptoms until the diagnosis. The western region showed the highest incidence and mortality by the disease over the other state mesoregions. During the period, a decreasing trend was observed in the confirmed cases and stability in the mortality rate with an average annual mortality of 1.17\u00a0per million\/inhabitants in the state; however, paracoccidioidomycosis had the highest mortality when compared to other mycoses.<\/jats:p><\/jats:sec><jats:sec><jats:title>Conclusions<\/jats:title><jats:p>Paracoccidioidomycosis is an important endemic mycosis in Paran\u00e1 and this study provides an epidemiological baseline for future modifications of paracoccidioidomycosis surveillance.<\/jats:p><\/jats:sec>","DOI":"10.1111\/myc.13417","type":"journal-article","created":{"date-parts":[[2021,12,22]],"date-time":"2021-12-22T14:32:52Z","timestamp":1640183572000},"page":"354-361","update-policy":"https:\/\/doi.org\/10.1002\/crossmark_policy","source":"Crossref","is-referenced-by-count":16,"title":["Compulsory notification of paracoccidioidomycosis: A 14\u2010year retrospective study of the disease in the state of Paran\u00e1, Brazil"],"prefix":"10.1111","volume":"65","author":[{"ORCID":"https:\/\/orcid.org\/0000-0001-7160-319X","authenticated-orcid":false,"given":"Igor Massahiro Souza","family":"de Suguiura","sequence":"first","affiliation":[{"name":"Divis\u00e3o de Vigil\u00e2ncia em Sa\u00fade 17a Regional de Sa\u00fade Secretaria de Estado da Sa\u00fade do Paran\u00e1 Londrina Brazil"},{"name":"Departamento de Ci\u00eancias Patol\u00f3gicas Centro de Ci\u00eancias Biol\u00f3gicas Universidade Estadual de Londrina Londrina Brazil"}],"role":[{"vocabulary":"crossref","role":"author"}]},{"ORCID":"https:\/\/orcid.org\/0000-0002-8691-5118","authenticated-orcid":false,"given":"Mario Augusto","family":"Ono","sequence":"additional","affiliation":[{"name":"Departamento de Ci\u00eancias Patol\u00f3gicas Centro de Ci\u00eancias Biol\u00f3gicas Universidade Estadual de Londrina Londrina Brazil"}],"role":[{"vocabulary":"crossref","role":"author"}]}],"member":"311","published-online":{"date-parts":[[2022,1,3]]},"reference":[{"key":"e_1_2_9_2_1","doi-asserted-by":"publisher","DOI":"10.1016\/j.ympev.2009.04.005"},{"key":"e_1_2_9_3_1","doi-asserted-by":"publisher","DOI":"10.1128\/mSphere.00213-16"},{"key":"e_1_2_9_4_1","doi-asserted-by":"publisher","DOI":"10.1016\/j.fgb.2017.05.007"},{"key":"e_1_2_9_5_1","doi-asserted-by":"publisher","DOI":"10.1590\/S0036-46652015000700004"},{"key":"e_1_2_9_6_1","doi-asserted-by":"publisher","DOI":"10.3390\/jof3010001"},{"key":"e_1_2_9_7_1","doi-asserted-by":"publisher","DOI":"10.1590\/S0037-86822011000500023"},{"key":"e_1_2_9_8_1","doi-asserted-by":"publisher","DOI":"10.4269\/ajtmh.2011.11-0084"},{"key":"e_1_2_9_9_1","doi-asserted-by":"publisher","DOI":"10.1590\/S0102-311X2002000500037"},{"key":"e_1_2_9_10_1","doi-asserted-by":"publisher","DOI":"10.1590\/S0102-311X2005000600035"},{"key":"e_1_2_9_11_1","first-page":"6","volume-title":"Protocolo de Paracoccidiodomicose","author":"SESA","year":"2002"},{"key":"e_1_2_9_12_1","doi-asserted-by":"publisher","DOI":"10.1590\/S0102-311X2003000100027"},{"key":"e_1_2_9_13_1","doi-asserted-by":"publisher","DOI":"10.1590\/S1806-37132007000300011"},{"key":"e_1_2_9_14_1","doi-asserted-by":"publisher","DOI":"10.1371\/journal.pntd.0003111"},{"key":"e_1_2_9_15_1","doi-asserted-by":"publisher","DOI":"10.1111\/myc.12819"}],"container-title":["Mycoses"],"original-title":[],"language":"en","link":[{"URL":"https:\/\/onlinelibrary.wiley.com\/doi\/pdf\/10.1111\/myc.13417","content-type":"application\/pdf","content-version":"vor","intended-application":"text-mining"},{"URL":"https:\/\/onlinelibrary.wiley.com\/doi\/full-xml\/10.1111\/myc.13417","content-type":"application\/xml","content-version":"vor","intended-application":"text-mining"},{"URL":"https:\/\/onlinelibrary.wiley.com\/doi\/pdf\/10.1111\/myc.13417","content-type":"unspecified","content-version":"vor","intended-application":"similarity-checking"}],"deposited":{"date-parts":[[2023,8,27]],"date-time":"2023-08-27T13:06:13Z","timestamp":1693141573000},"score":1,"resource":{"primary":{"URL":"https:\/\/onlinelibrary.wiley.com\/doi\/10.1111\/myc.13417"}},"subtitle":[],"short-title":[],"issued":{"date-parts":[[2022,1,3]]},"references-count":14,"journal-issue":{"issue":"3","published-print":{"date-parts":[[2022,3]]}},"alternative-id":["10.1111\/myc.13417"],"URL":"https:\/\/doi.org\/10.1111\/myc.13417","archive":["Portico"],"relation":{},"ISSN":["0933-7407","1439-0507"],"issn-type":[{"value":"0933-7407","type":"print"},{"value":"1439-0507","type":"electronic"}],"subject":[],"published":{"date-parts":[[2022,1,3]]},"assertion":[{"value":"2021-09-04","order":0,"name":"received","label":"Received","group":{"name":"publication_history","label":"Publication History"}},{"value":"2021-12-17","order":1,"name":"accepted","label":"Accepted","group":{"name":"publication_history","label":"Publication History"}},{"value":"2022-01-03","order":2,"name":"published","label":"Published","group":{"name":"publication_history","label":"Publication History"}}]}}