{"status":"ok","message-type":"work","message-version":"1.0.0","message":{"indexed":{"date-parts":[[2026,1,24]],"date-time":"2026-01-24T06:57:17Z","timestamp":1769237837802,"version":"3.49.0"},"reference-count":10,"publisher":"Wiley","issue":"5","license":[{"start":{"date-parts":[[2022,4,8]],"date-time":"2022-04-08T00:00:00Z","timestamp":1649376000000},"content-version":"vor","delay-in-days":0,"URL":"http:\/\/onlinelibrary.wiley.com\/termsAndConditions#vor"}],"content-domain":{"domain":["onlinelibrary.wiley.com"],"crossmark-restriction":true},"short-container-title":["Mycoses"],"published-print":{"date-parts":[[2022,5]]},"abstract":"<jats:title>Abstract<\/jats:title><jats:sec><jats:title>Background<\/jats:title><jats:p>The sudden surge of mucormycosis cases which happened during the second wave of COVID\u201019 pandemic was a significant public health problem in India.<\/jats:p><\/jats:sec><jats:sec><jats:title>Objectives<\/jats:title><jats:p>The aim of this study was to analyse the clinico\u2010epidemicological characteristics of the mucormycosis cases to determine the changes that had occurred due to COVID\u201019 pandemic.<\/jats:p><\/jats:sec><jats:sec><jats:title>Methodology<\/jats:title><jats:p>A retrospective cross\u2010sectional study was conducted at the Department of Otolaryngology Head and Neck Surgery, PGIMER, Chandigarh, India. Patients diagnosed with rhino\u2010orbital mucormycosis were categorised into the following groups: <jats:italic>Pre\u2010pandemic<\/jats:italic>(May 2019 to April 2020), <jats:italic>Pandemic Pre\u2010epidemic<\/jats:italic> (May 2020 to April 2021) and <jats:italic>Epidemic<\/jats:italic> (1 May 2021 to 12 July 2021). The epidemiological, clinical and surgical data of all the patients were retrieved from the hospital records and analysed.<\/jats:p><\/jats:sec><jats:sec><jats:title>Results<\/jats:title><jats:p>The <jats:italic>epidemic<\/jats:italic> period had 370 cases, compared with 65 during <jats:italic>pandemic<\/jats:italic> period and 42 in the <jats:italic>pre\u2010pandemic period<\/jats:italic>. Diabetes mellitus was seen in 87% of cases during <jats:italic>epidemic<\/jats:italic> period, 92.9% in the <jats:italic>pre\u2010pandemic<\/jats:italic> period and 90.8% in the <jats:italic>pre\u2010pandemic pre\u2010epidemic<\/jats:italic> period. The proportion of patients suffering from vision loss, restricted extra\u2010ocular movements, palatal ulcer and nasal obstruction was higher in the pre\u2010epidemic groups, and the difference was significant (<jats:italic>p<\/jats:italic>, &lt;.01). There was no history of oxygen use in 85.9% of patients and no steroid use in 76.5%. The death rates were the lowest during epidemic (10%).<\/jats:p><\/jats:sec><jats:sec><jats:title>Conclusion<\/jats:title><jats:p>COVID\u201019 has caused a statistically significant increase in the number of mucormycosis infections. The mortality and morbidity which showed an increase during the first wave of COVID\u201019 decreased significantly during the epidemic period.<\/jats:p><\/jats:sec>","DOI":"10.1111\/myc.13437","type":"journal-article","created":{"date-parts":[[2022,3,15]],"date-time":"2022-03-15T08:39:40Z","timestamp":1647333580000},"page":"567-576","update-policy":"https:\/\/doi.org\/10.1002\/crossmark_policy","source":"Crossref","is-referenced-by-count":9,"title":["As the virus sowed, the fungus reaped! A comparative analysis of the clinico\u2010epidemiological characteristics of rhino\u2010orbital mucormycosis before and during COVID\u201019 pandemic"],"prefix":"10.1111","volume":"65","author":[{"given":"Manjul","family":"Muraleedharan","sequence":"first","affiliation":[{"name":"Department of Otolaryngology Head and Neck Surgery Postgraduate Institute of Medical Education and Research  Chandigarh India"}],"role":[{"role":"author","vocabulary":"crossref"}]},{"ORCID":"https:\/\/orcid.org\/0000-0002-1767-7013","authenticated-orcid":false,"given":"Naresh Kumar","family":"Panda","sequence":"additional","affiliation":[{"name":"Department of Otolaryngology Head and Neck Surgery Postgraduate Institute of Medical Education and Research  Chandigarh India"}],"role":[{"role":"author","vocabulary":"crossref"}]},{"given":"Prerna","family":"Angrish","sequence":"additional","affiliation":[{"name":"Department of Otolaryngology Head and Neck Surgery Postgraduate Institute of Medical Education and Research  Chandigarh India"}],"role":[{"role":"author","vocabulary":"crossref"}]},{"given":"Kanika","family":"Arora","sequence":"additional","affiliation":[{"name":"Department of Otolaryngology Head and Neck Surgery Postgraduate Institute of Medical Education and Research  Chandigarh India"}],"role":[{"role":"author","vocabulary":"crossref"}]},{"ORCID":"https:\/\/orcid.org\/0000-0002-4819-7928","authenticated-orcid":false,"given":"Sourabha Kumar","family":"Patro","sequence":"additional","affiliation":[{"name":"Department of Otolaryngology Head and Neck Surgery Postgraduate Institute of Medical Education and Research  Chandigarh India"}],"role":[{"role":"author","vocabulary":"crossref"}]},{"given":"Sandeep","family":"Bansal","sequence":"additional","affiliation":[{"name":"Department of Otolaryngology Head and Neck Surgery Postgraduate Institute of Medical Education and Research  Chandigarh India"}],"role":[{"role":"author","vocabulary":"crossref"}]},{"given":"Arunaloke","family":"Chakrabarti","sequence":"additional","affiliation":[{"name":"Department of Medical Microbiology Postgraduate Institute of Medical Education and Research  Chandigarh India"}],"role":[{"role":"author","vocabulary":"crossref"}]},{"ORCID":"https:\/\/orcid.org\/0000-0002-9097-9253","authenticated-orcid":false,"given":"Shivaprakash Mandya","family":"Rudramurthy","sequence":"additional","affiliation":[{"name":"Department of Medical Microbiology Postgraduate Institute of Medical Education and Research  Chandigarh India"}],"role":[{"role":"author","vocabulary":"crossref"}]},{"given":"Jaimanti","family":"Bakshi","sequence":"additional","affiliation":[{"name":"Department of Otolaryngology Head and Neck Surgery Postgraduate Institute of Medical Education and Research  Chandigarh India"}],"role":[{"role":"author","vocabulary":"crossref"}]},{"given":"Satyawati","family":"Mohindra","sequence":"additional","affiliation":[{"name":"Department of Otolaryngology Head and Neck Surgery Postgraduate Institute of Medical Education and Research  Chandigarh India"}],"role":[{"role":"author","vocabulary":"crossref"}]},{"given":"Rijuneeta","family":"Gupta","sequence":"additional","affiliation":[{"name":"Department of Otolaryngology Head and Neck Surgery Postgraduate Institute of Medical Education and Research  Chandigarh India"}],"role":[{"role":"author","vocabulary":"crossref"}]},{"given":"Ramandeep Singh","family":"Virk","sequence":"additional","affiliation":[{"name":"Department of Otolaryngology Head and Neck Surgery Postgraduate Institute of Medical Education and Research  Chandigarh India"}],"role":[{"role":"author","vocabulary":"crossref"}]},{"given":"Roshan Kumar","family":"Verma","sequence":"additional","affiliation":[{"name":"Department of Otolaryngology Head and Neck Surgery Postgraduate Institute of Medical Education and Research  Chandigarh India"}],"role":[{"role":"author","vocabulary":"crossref"}]},{"given":"Anurag Snehi","family":"Ramavat","sequence":"additional","affiliation":[{"name":"Department of Otolaryngology Head and Neck Surgery Postgraduate Institute of Medical Education and Research  Chandigarh India"}],"role":[{"role":"author","vocabulary":"crossref"}]},{"given":"Gyanaranjan","family":"Nayak","sequence":"additional","affiliation":[{"name":"Department of Otolaryngology Head and Neck Surgery Postgraduate Institute of Medical Education and Research  Chandigarh India"}],"role":[{"role":"author","vocabulary":"crossref"}]}],"member":"311","published-online":{"date-parts":[[2022,4,8]]},"reference":[{"key":"e_1_2_9_2_1","doi-asserted-by":"publisher","DOI":"10.1093\/mmy\/myy060"},{"key":"e_1_2_9_3_1","doi-asserted-by":"publisher","DOI":"10.4103\/ijo.IJO_1565_21"},{"key":"e_1_2_9_4_1","doi-asserted-by":"publisher","DOI":"10.1016\/j.ijid.2021.08.037"},{"key":"e_1_2_9_5_1","doi-asserted-by":"publisher","DOI":"10.1017\/S0022215121000992"},{"key":"e_1_2_9_6_1","doi-asserted-by":"publisher","DOI":"10.4187\/respcare.03174"},{"key":"e_1_2_9_7_1","doi-asserted-by":"publisher","DOI":"10.1053\/jinf.2001.0831"},{"key":"e_1_2_9_8_1","doi-asserted-by":"publisher","DOI":"10.1111\/j.1439-0507.2007.01364.x"},{"key":"e_1_2_9_9_1","doi-asserted-by":"publisher","DOI":"10.3390\/jof7080616"},{"key":"e_1_2_9_10_1","doi-asserted-by":"publisher","DOI":"10.1016\/j.amjoto.2006.01.002"},{"key":"e_1_2_9_11_1","doi-asserted-by":"publisher","DOI":"10.2310\/7070.2005.34607"}],"container-title":["Mycoses"],"original-title":[],"language":"en","link":[{"URL":"https:\/\/onlinelibrary.wiley.com\/doi\/pdf\/10.1111\/myc.13437","content-type":"application\/pdf","content-version":"vor","intended-application":"text-mining"},{"URL":"https:\/\/onlinelibrary.wiley.com\/doi\/full-xml\/10.1111\/myc.13437","content-type":"application\/xml","content-version":"vor","intended-application":"text-mining"},{"URL":"https:\/\/onlinelibrary.wiley.com\/doi\/pdf\/10.1111\/myc.13437","content-type":"unspecified","content-version":"vor","intended-application":"similarity-checking"}],"deposited":{"date-parts":[[2023,8,22]],"date-time":"2023-08-22T19:43:58Z","timestamp":1692733438000},"score":1,"resource":{"primary":{"URL":"https:\/\/onlinelibrary.wiley.com\/doi\/10.1111\/myc.13437"}},"subtitle":[],"short-title":[],"issued":{"date-parts":[[2022,4,8]]},"references-count":10,"journal-issue":{"issue":"5","published-print":{"date-parts":[[2022,5]]}},"alternative-id":["10.1111\/myc.13437"],"URL":"https:\/\/doi.org\/10.1111\/myc.13437","archive":["Portico"],"relation":{},"ISSN":["0933-7407","1439-0507"],"issn-type":[{"value":"0933-7407","type":"print"},{"value":"1439-0507","type":"electronic"}],"subject":[],"published":{"date-parts":[[2022,4,8]]},"assertion":[{"value":"2022-02-04","order":0,"name":"received","label":"Received","group":{"name":"publication_history","label":"Publication History"}},{"value":"2022-03-08","order":1,"name":"accepted","label":"Accepted","group":{"name":"publication_history","label":"Publication History"}},{"value":"2022-04-08","order":2,"name":"published","label":"Published","group":{"name":"publication_history","label":"Publication History"}}]}}