{"status":"ok","message-type":"work","message-version":"1.0.0","message":{"indexed":{"date-parts":[[2026,8,24]],"date-time":"2026-08-24T23:46:01Z","timestamp":1787615161752,"version":"build-2736575974"},"reference-count":44,"publisher":"Wiley","issue":"7","license":[{"start":{"date-parts":[[2022,5,31]],"date-time":"2022-05-31T00:00:00Z","timestamp":1653955200000},"content-version":"vor","delay-in-days":0,"URL":"http:\/\/creativecommons.org\/licenses\/by-nc-nd\/4.0\/"}],"funder":[{"DOI":"10.13039\/501100001665","name":"Agence Nationale de la Recherche","doi-asserted-by":"publisher","id":[{"id":"10.13039\/501100001665","id-type":"DOI","asserted-by":"publisher"}]}],"content-domain":{"domain":["onlinelibrary.wiley.com"],"crossmark-restriction":true},"short-container-title":["Mycoses"],"published-print":{"date-parts":[[2022,7]]},"abstract":"<jats:title>Abstract<\/jats:title><jats:sec><jats:title>Background<\/jats:title><jats:p>Currently, <jats:italic>Candida auris<\/jats:italic> is among the most serious emerging pathogens that can be associated with nosocomial infections and outbreaks in intensive care units. Clinicians must be able to identify and manage it quickly.<\/jats:p><\/jats:sec><jats:sec><jats:title>Objective<\/jats:title><jats:p>Here, we report for the first time in Algeria seven cases of <jats:italic>C.\u00a0auris<\/jats:italic> infection or colonisation.<\/jats:p><\/jats:sec><jats:sec><jats:title>Methods and Results<\/jats:title><jats:p>The strains were isolated from clinical sites including bronchial aspirates (<jats:italic>n<\/jats:italic>\u00a0=\u00a04), wound swabs (<jats:italic>n<\/jats:italic>\u00a0=\u00a01), urine sample (<jats:italic>n<\/jats:italic>\u00a0=\u00a01) and peritoneal fluid (<jats:italic>n<\/jats:italic>\u00a0=\u00a01), in patients admitted to the intensive care unit. <jats:italic>Candida auris<\/jats:italic> was identified both by MALDI\u2010TOF and by sequencing the ITS region and the D1\/D2 domain. Antifungal susceptibility testing was performed using the <jats:italic>E<\/jats:italic>\u2010test method. Non\u2010wildtype susceptibility was observed for five strains against fluconazole, itraconazole, voriconazole and caspofungin. Genotyping showed the presence of four clades (I\u2013IV) in one hospital.<\/jats:p><\/jats:sec><jats:sec><jats:title>Conclusions<\/jats:title><jats:p>Appropriate antifungal treatments with rapid and accurate microbial identification are the cornerstone for the management and control of <jats:italic>C.\u00a0auris<\/jats:italic> infections.<\/jats:p><\/jats:sec>","DOI":"10.1111\/myc.13470","type":"journal-article","created":{"date-parts":[[2022,5,12]],"date-time":"2022-05-12T08:05:55Z","timestamp":1652342755000},"page":"753-759","update-policy":"https:\/\/doi.org\/10.1002\/crossmark_policy","source":"Crossref","is-referenced-by-count":24,"title":["Emergence of <i>Candida auris<\/i> in intensive care units in Algeria"],"prefix":"10.1111","volume":"65","author":[{"given":"Hanane","family":"Zerrouki","sequence":"first","affiliation":[{"name":"Aix\u2010Marseille Universit\u00e9, IRD, APHM, MEPHI  Marseille France"},{"name":"IHU\u2010M\u00e9diterran\u00e9e Infection  Marseille 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\u00e0 l'Environnement Universit\u00e9 de Tlemcen  Tlemcen Algeria"}],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Djamel\u2010Eddine","family":"Benhaddouche","sequence":"additional","affiliation":[{"name":"Service d'anesth\u00e9sie et de r\u00e9animation Centre Hospitalo\u2010Universitaire Tlemcen  Tlemcen Algeria"}],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Theun","family":"de Groot","sequence":"additional","affiliation":[{"name":"Department of Medical Microbiology and Infectious Diseases Canisius\u2010Wilhelmina Hospital  Nijmegen The Netherlands"},{"name":"Centre of Expertise in Mycology Radboudumc\/Canisius Wilhelmina Hospital  Nijmegen The Netherlands"}],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Jacques F.","family":"Meis","sequence":"additional","affiliation":[{"name":"Department of Medical Microbiology and Infectious Diseases Canisius\u2010Wilhelmina Hospital  Nijmegen The Netherlands"},{"name":"Centre of Expertise in 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