{"status":"ok","message-type":"work","message-version":"1.0.0","message":{"indexed":{"date-parts":[[2026,8,5]],"date-time":"2026-08-05T11:13:32Z","timestamp":1785928412264,"version":"3.56.0"},"reference-count":43,"publisher":"Wiley","issue":"11","license":[{"start":{"date-parts":[[2022,7,18]],"date-time":"2022-07-18T00:00:00Z","timestamp":1658102400000},"content-version":"vor","delay-in-days":0,"URL":"http:\/\/onlinelibrary.wiley.com\/termsAndConditions#vor"}],"funder":[{"DOI":"10.13039\/501100008257","name":"Tarbiat Modares University","doi-asserted-by":"publisher","id":[{"id":"10.13039\/501100008257","id-type":"DOI","asserted-by":"publisher"}]}],"content-domain":{"domain":["onlinelibrary.wiley.com"],"crossmark-restriction":true},"short-container-title":["Mycoses"],"published-print":{"date-parts":[[2022,11]]},"abstract":"<jats:title>Abstract<\/jats:title><jats:p>Onychomycosis, a nail fungal infection, is normally caused by dermatophytes. However, yeasts and non\u2010dermatophyte moulds (NDM) are among pathogens that cause nail disease. Regarding, this study aimed to describe the molecular epidemiology of <jats:italic>Fusarium<\/jats:italic> onychomycosis in the North of Iran. Two hundred and fifty seven nail samples collected from the patients clinically suspected of onychomycosis were subjected to direct microscopy, calcofluor white staining and culture. <jats:italic>Fusarium<\/jats:italic> isolates were identified at a species level through determination of multi\u2010locus sequences for internal transcribed spacer and translation elongation factor 1 alpha. Based on the findings, <jats:italic>Fusarium<\/jats:italic> species were isolated from onychomycosis patients (<jats:italic>n<\/jats:italic>\u00a0=\u00a027). According to a previous partial genes analysis, the species in the recent study belonged to the members of <jats:italic>F.\u00a0fujikuroi<\/jats:italic> species complex (<jats:italic>n<\/jats:italic>\u00a0=\u00a014), <jats:italic>Fusarium incarnatum\u2010equiseti<\/jats:italic> species complex (<jats:italic>n<\/jats:italic>\u00a0=\u00a01) and <jats:italic>F.\u00a0solani<\/jats:italic> species complex (<jats:italic>n<\/jats:italic>\u00a0=\u00a012). In this study, <jats:italic>F.\u00a0proliferatum<\/jats:italic> was the dominant <jats:italic>Fusarium<\/jats:italic> species collected from the samples. The correct identification of <jats:italic>Fusarium<\/jats:italic> species is essential regarding the increased prevalence of <jats:italic>Fusarium<\/jats:italic> onychomycosis and the inherent resistance of these agents to a wide spectrum of antifungals. The obtained results indicated variation in the epidemiology of <jats:italic>Fusarium<\/jats:italic> species isolated from onychomycosis. Moreover, the minimum inhibitory concentration (MIC) of luliconazole and lanoconazole was in the range of 0.001\u20131\u00a0\u03bcg\/ml, with the geometric mean of MICs obtained at 0.0103 and 0.0343\u2009\u03bcg\/ml against <jats:italic>Fusarium<\/jats:italic> species, respectively. These findings can increase researchers' knowledge regarding diversity of species, distribution of onychomycosis and the choice of a proper treatment.<\/jats:p>","DOI":"10.1111\/myc.13489","type":"journal-article","created":{"date-parts":[[2022,7,1]],"date-time":"2022-07-01T12:39:27Z","timestamp":1656679167000},"page":"1030-1039","update-policy":"https:\/\/doi.org\/10.1002\/crossmark_policy","source":"Crossref","is-referenced-by-count":5,"title":["Prevalence, genetic diversity and antifungal susceptibility profiles of <i>F.\u00a0fujikuroi<\/i>, <i>F.\u00a0solani<\/i> and <i>Fusarium incarnatum\u2010equiseti<\/i> species complexes from onychomycosis in north of Iran"],"prefix":"10.1111","volume":"65","author":[{"given":"Iman","family":"Haghani","sequence":"first","affiliation":[{"name":"Department of Mycology, Faculty of Medical Sciences Tarbiat Modares University  Tehran Iran"},{"name":"Department of Medical Mycology and Invasive Fungi Research Center, Communicable Diseases Institute Mazandaran University of Medical Sciences  Sari Iran"}],"role":[{"vocabulary":"crossref","role":"author"}]},{"ORCID":"https:\/\/orcid.org\/0000-0003-2562-965X","authenticated-orcid":false,"given":"Masoomeh","family":"Shams\u2010Ghahfarokhi","sequence":"additional","affiliation":[{"name":"Department of Mycology, Faculty of Medical Sciences Tarbiat Modares University  Tehran Iran"}],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Abdolhossein","family":"Dalimi Asl","sequence":"additional","affiliation":[{"name":"Department of Medical Parasitology, Faculty of Medical Sciences Tarbiat Modares University  Tehran Iran"}],"role":[{"vocabulary":"crossref","role":"author"}]},{"ORCID":"https:\/\/orcid.org\/0000-0003-3094-8436","authenticated-orcid":false,"given":"Tahereh","family":"Shokohi","sequence":"additional","affiliation":[{"name":"Department of Medical Mycology and Invasive Fungi Research Center, Communicable Diseases Institute Mazandaran University of Medical Sciences  Sari Iran"}],"role":[{"vocabulary":"crossref","role":"author"}]},{"ORCID":"https:\/\/orcid.org\/0000-0001-6415-4648","authenticated-orcid":false,"given":"Mohammad Taghi","family":"Hedayati","sequence":"additional","affiliation":[{"name":"Department of Medical Mycology and Invasive Fungi Research Center, Communicable Diseases Institute Mazandaran University of Medical Sciences  Sari 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