{"status":"ok","message-type":"work","message-version":"1.0.0","message":{"indexed":{"date-parts":[[2026,9,18]],"date-time":"2026-09-18T04:20:04Z","timestamp":1789705204083,"version":"4.0.1"},"reference-count":27,"publisher":"Wiley","issue":"2","license":[{"start":{"date-parts":[[2022,9,27]],"date-time":"2022-09-27T00:00:00Z","timestamp":1664236800000},"content-version":"vor","delay-in-days":0,"URL":"http:\/\/creativecommons.org\/licenses\/by-nc-nd\/4.0\/"}],"content-domain":{"domain":["onlinelibrary.wiley.com"],"crossmark-restriction":true},"short-container-title":["Mycoses"],"published-print":{"date-parts":[[2023,2]]},"abstract":"<jats:title>Abstract<\/jats:title><jats:sec><jats:title>Introduction<\/jats:title><jats:p><jats:italic>Candida auris<\/jats:italic> is an emerging pathogen in health care\u2010associated infections. In contrast to many other countries with rising numbers of <jats:italic>C.\u00a0auris<\/jats:italic>, only seven cases have been reported in Germany from 2015 to 2017, mostly from patients who received prior medical treatment abroad. We therefore established a mandatory screening for <jats:italic>C.\u00a0auris<\/jats:italic> colonisation at our tertiary care centre for all patients who were admitted as international patients or previously hospitalised in a foreign country within the past 6\u2009months.<\/jats:p><\/jats:sec><jats:sec><jats:title>Methods<\/jats:title><jats:p>Colonisation of patients was assessed using a previously established screening protocol for multidrug resistant bacteria. Since 2017, all screening samples were additionally analysed for <jats:italic>C.\u00a0auris<\/jats:italic> using CHROMagar Candida (CHROMagar, Paris, France). Yeast isolates were identified using matrix\u2010assisted laser ionisation time\u2010of\u2010flight (MALDI TOF), except for <jats:italic>C.\u00a0albicans<\/jats:italic> (identified by the typical green colour on chromogenic agar). Data were analysed retrospectively.<\/jats:p><\/jats:sec><jats:sec><jats:title>Results<\/jats:title><jats:p>Our study cohort included 655 patients and an overall number of 1399 samples. Fifty\u2010three patients were colonised with <jats:italic>Candida<\/jats:italic> species (<jats:italic>C.\u00a0albicans, n\u2009=<\/jats:italic>\u00a037; <jats:italic>C.\u00a0glabrata, n\u2009=<\/jats:italic>\u00a014; others <jats:italic>n\u2009=<\/jats:italic>\u00a09). No case of <jats:italic>C.\u00a0auris<\/jats:italic> was detected. <jats:italic>Candida<\/jats:italic> spp. were mainly detected from respiratory samples (5.4% positive) and gastrointestinal specimen (5.2%). Laboratory costs were 14,689 \u20ac and analyses resulted in 98.7\u2009h of additional technician's work.<\/jats:p><\/jats:sec><jats:sec><jats:title>Conclusion<\/jats:title><jats:p>No colonisation with <jats:italic>C.\u00a0auris<\/jats:italic> was detected among patients with previous hospitalisation abroad. Universal <jats:italic>C.\u00a0auris<\/jats:italic> screening of patients with any contact to foreign health care does not seem to be cost\u2010effective in our setting and more targeted screening strategies have to be developed.<\/jats:p><\/jats:sec>","DOI":"10.1111\/myc.13533","type":"journal-article","created":{"date-parts":[[2022,9,22]],"date-time":"2022-09-22T12:44:06Z","timestamp":1663850646000},"page":"138-143","update-policy":"https:\/\/doi.org\/10.1002\/crossmark_policy","source":"Crossref","is-referenced-by-count":13,"title":["Usefulness of screening for <i>Candida auris<\/i> colonisation in international patients admitted to a large university hospital"],"prefix":"10.1111","volume":"66","author":[{"ORCID":"https:\/\/orcid.org\/0000-0002-5520-3038","authenticated-orcid":false,"given":"Judith","family":"Heindel","sequence":"first","affiliation":[{"name":"Institute for Medical Microbiology, Immunology and Hygiene University of Cologne, Medical Faculty and University Hospital of Cologne  Cologne Germany"}],"role":[{"vocabulary":"crossref","role":"author"}]},{"ORCID":"https:\/\/orcid.org\/0000-0002-0360-434X","authenticated-orcid":false,"given":"Janine","family":"Zweigner","sequence":"additional","affiliation":[{"name":"Department of Infection Control and Hospital Hygiene University Hospital Cologne  Cologne Germany"}],"role":[{"vocabulary":"crossref","role":"author"}]},{"ORCID":"https:\/\/orcid.org\/0000-0001-7075-5378","authenticated-orcid":false,"given":"Frieder","family":"Fuchs","sequence":"additional","affiliation":[{"name":"Institute for Medical Microbiology, Immunology and Hygiene University of Cologne, Medical Faculty and University Hospital of Cologne  Cologne Germany"}],"role":[{"vocabulary":"crossref","role":"author"}]},{"ORCID":"https:\/\/orcid.org\/0000-0003-1449-5780","authenticated-orcid":false,"given":"Axel","family":"Hamprecht","sequence":"additional","affiliation":[{"name":"Institute for Medical Microbiology, Immunology and Hygiene University of Cologne, Medical Faculty and University Hospital of Cologne  Cologne Germany"},{"name":"German Centre for Infection Research (DZIF) Partner Site Bonn\u2010Cologne  Cologne Germany"},{"name":"Institute for Medical Microbiology and Virology University of Oldenburg  Oldenburg Germany"}],"role":[{"vocabulary":"crossref","role":"author"}]}],"member":"311","published-online":{"date-parts":[[2022,9,27]]},"reference":[{"key":"e_1_2_9_2_1","doi-asserted-by":"publisher","DOI":"10.1186\/s13756-016-0132-5"},{"key":"e_1_2_9_3_1","doi-asserted-by":"publisher","DOI":"10.1093\/cid\/ciw691"},{"key":"e_1_2_9_4_1","doi-asserted-by":"publisher","DOI":"10.1128\/JCM.00367-15"},{"key":"e_1_2_9_5_1","doi-asserted-by":"publisher","DOI":"10.1111\/j.1348-0421.2008.00083.x"},{"key":"e_1_2_9_6_1","unstructured":"European Centre for Disease Prevention and Control.Rapid Risk Assessment:Candida AurisOutbreak in Healthcare Facilities in Northern Italy 2019\u20102021;2022. 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