{"status":"ok","message-type":"work","message-version":"1.0.0","message":{"indexed":{"date-parts":[[2026,9,11]],"date-time":"2026-09-11T03:04:56Z","timestamp":1789095896538,"version":"build-2803163510"},"reference-count":20,"publisher":"Wiley","issue":"2","license":[{"start":{"date-parts":[[2022,10,27]],"date-time":"2022-10-27T00:00:00Z","timestamp":1666828800000},"content-version":"vor","delay-in-days":0,"URL":"http:\/\/onlinelibrary.wiley.com\/termsAndConditions#vor"}],"content-domain":{"domain":["onlinelibrary.wiley.com"],"crossmark-restriction":true},"short-container-title":["Mycoses"],"published-print":{"date-parts":[[2023,2]]},"abstract":"<jats:title>Abstract<\/jats:title><jats:sec><jats:title>Background<\/jats:title><jats:p><jats:italic>Trichophyton tonsurans<\/jats:italic> tinea capitis has become a growing epidemiological concern. Yet, its clinical manifestations and treatment response, specifically among adults, have only been described among small sample size studies.<\/jats:p><\/jats:sec><jats:sec><jats:title>Objective<\/jats:title><jats:p>To assess clinical manifestations and treatment outcome of <jats:italic>T. tonsurans<\/jats:italic> tinea capitis among adults.<\/jats:p><\/jats:sec><jats:sec><jats:title>Patients and Methods<\/jats:title><jats:p>A retrospective cohort study was carried out among 111 adults with <jats:italic>T. tonsurans<\/jats:italic> tinea capitis. Diagnosis was confirmed by fungal culture or polymerase chain reaction. Examinees' demographics, disease characteristics and treatment response were measured. The risk factors for the treatment failure were evaluated.<\/jats:p><\/jats:sec><jats:sec><jats:title>Results<\/jats:title><jats:p>The mean age was 20.1\u2009years (\u00b13.1), with men (98.2%) outnumbering women. The follow\u2010up lasted 12.2\u2009months (\u00b15.6). The majority of <jats:italic>T. tonsurans<\/jats:italic> tinea capitis was seen in the occipital area (87.6%). In 78.9% of the cases, the scalp manifestation was non\u2010inflammatory (scaly plaques and papules:76.1% and seborrhoea\u2010like: 2.8%). 21.1% of cases presented with inflammatory tinea capitis (21.1%; Kerion: 10.1% and pustular: 11%). Concomitant involvement of other than scalp areas was common: tinea corporis was seen in 38.7% of the cases; tinea faciei and barbae in 24.3%; nape and anterior neck in 76.6% and 2.7% of the cases, respectively. An adequate treatment course with oral terbinafine resulted in 83.2% clinical cure rate. Treatment failure was significantly associated with concomitant tinea corporis (odds ratio 3.9; 95% confidence interval 1.3\u201312.1, <jats:italic>p<\/jats:italic>\u2010Value&lt; .02).<\/jats:p><\/jats:sec><jats:sec><jats:title>Conclusion<\/jats:title><jats:p>The most common clinical presentation of <jats:italic>T. tonsurans<\/jats:italic> tinea capitis included occipital scaly plaques and papules with concomitant non\u2010scalp lesions. Oral terbinafine was found to be highly effective. Concomitant tinea corporis increased the risk for treatment failure.<\/jats:p><\/jats:sec>","DOI":"10.1111\/myc.13536","type":"journal-article","created":{"date-parts":[[2022,10,11]],"date-time":"2022-10-11T16:11:39Z","timestamp":1665504699000},"page":"144-149","update-policy":"https:\/\/doi.org\/10.1002\/crossmark_policy","source":"Crossref","is-referenced-by-count":6,"title":["Tinea capitis caused by Trichophyton tonsurans among adults: Clinical characteristics and treatment response"],"prefix":"10.1111","volume":"66","author":[{"ORCID":"https:\/\/orcid.org\/0000-0003-1518-6875","authenticated-orcid":false,"given":"Eran","family":"Galili","sequence":"first","affiliation":[{"name":"Department of Dermatology Sheba Medical Center  Tel\u2010Hashomer, Ramat\u2010Gan Israel"},{"name":"Sackler Faculty of Medicine Tel Aviv University  Tel Aviv Israel"}],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Tomer","family":"Goldsmith","sequence":"additional","affiliation":[{"name":"Sackler Faculty of Medicine Tel Aviv University  Tel Aviv Israel"},{"name":"Department of Dermatology Tel Aviv Sourasky Medical Center  Tel Aviv Israel"}],"role":[{"vocabulary":"crossref","role":"author"}]},{"ORCID":"https:\/\/orcid.org\/0000-0001-5983-4091","authenticated-orcid":false,"given":"Israel","family":"Khanimov","sequence":"additional","affiliation":[{"name":"Israel Defense Forces Medical Corps  Tel Hashomer, Ramat Gan Israel"},{"name":"Division of Dermatology Rabin Medical Center  Petah Tikva Israel"}],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Chen","family":"Arbel","sequence":"additional","affiliation":[{"name":"Israel Defense Forces Medical Corps  Tel Hashomer, Ramat Gan Israel"}],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Sharon","family":"Sharvit","sequence":"additional","affiliation":[{"name":"Israel Defense Forces Medical Corps  Tel Hashomer, Ramat Gan Israel"}],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Anna","family":"Lyakhovitsky","sequence":"additional","affiliation":[{"name":"Department of Dermatology Sheba Medical Center  Tel\u2010Hashomer, Ramat\u2010Gan Israel"},{"name":"Sackler Faculty of Medicine Tel Aviv University  Tel Aviv Israel"}],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Avner","family":"Shemer","sequence":"additional","affiliation":[{"name":"Department of Dermatology Sheba Medical Center  Tel\u2010Hashomer, Ramat\u2010Gan Israel"},{"name":"Sackler Faculty of Medicine Tel Aviv University  Tel Aviv Israel"}],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Aviv","family":"Barzilai","sequence":"additional","affiliation":[{"name":"Department of Dermatology Sheba Medical Center  Tel\u2010Hashomer, Ramat\u2010Gan Israel"},{"name":"Sackler Faculty of Medicine Tel Aviv University  Tel Aviv Israel"}],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Nadav","family":"Astman","sequence":"additional","affiliation":[{"name":"Department of Dermatology Sheba Medical Center  Tel\u2010Hashomer, Ramat\u2010Gan Israel"},{"name":"Sackler Faculty of Medicine Tel Aviv University  Tel Aviv Israel"},{"name":"Israel Defense Forces Medical Corps  Tel Hashomer, Ramat Gan Israel"}],"role":[{"vocabulary":"crossref","role":"author"}]}],"member":"311","published-online":{"date-parts":[[2022,10,27]]},"reference":[{"key":"e_1_2_8_2_1","doi-asserted-by":"publisher","DOI":"10.1007\/s11046-016-0082-8"},{"issue":"8","key":"e_1_2_8_3_1","doi-asserted-by":"crossref","first-page":"818","DOI":"10.1111\/ddg.12885","article-title":"Tinea capitis: temporal shift in pathogens and epidemiology","volume":"14","author":"Ziegler W","year":"2016","journal-title":"J Dtsch 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