{"status":"ok","message-type":"work","message-version":"1.0.0","message":{"indexed":{"date-parts":[[2026,10,12]],"date-time":"2026-10-12T16:11:42Z","timestamp":1791821502843,"version":"4.3.4"},"reference-count":30,"publisher":"Wiley","issue":"7","license":[{"start":{"date-parts":[[2023,3,7]],"date-time":"2023-03-07T00:00:00Z","timestamp":1678147200000},"content-version":"vor","delay-in-days":0,"URL":"http:\/\/onlinelibrary.wiley.com\/termsAndConditions#vor"}],"content-domain":{"domain":["onlinelibrary.wiley.com"],"crossmark-restriction":true},"short-container-title":["Mycoses"],"published-print":{"date-parts":[[2023,7]]},"abstract":"<jats:title>Abstract<\/jats:title>\n                  <jats:p>\n                    <jats:italic>Mucorales<\/jats:italic>\n                    fungi cause mucormycosis, an invasive and rapidly progressive disease which increasingly affects mostly immunocompromised but also immunocompetent individuals. The objective of this study was to highlight the epidemiology, diagnostic modalities, treatment and overall survival of mucormycosis in Africa. We searched for relevant publications in PubMed, Google Scholar and African Journal Online databases covering the period 1960\u20132022. A total of 147 articles were identified, of which 66 were included in the review, detailing 408 individual cases from 12 African countries; 330 (80.9%) from North Africa, 63 (15.4%) from Southern Africa, seven (1.7%) from East Africa, seven (1.7%) from West Africa and a single case (0.2%) from Central Africa. The most frequently described clinical forms were rhino\u2010orbital\u2010cerebral (\n                    <jats:italic>n<\/jats:italic>\n                    \u00a0=\u00a0307, 75.2%) and gastrointestinal (\n                    <jats:italic>n<\/jats:italic>\n                    \u00a0=\u00a051, 12.5%). Diabetes mellitus, COVID\u201019, malignancies and neutropaenia were the commonest underlying risks in 203 (49.8%), 101 (24.8%), 65 (15.9%) and 53 (13.0%) cases respectively. Most cases, 296 (72.5%) were diagnosed by histopathology. Fungal aetiology was identified in 38 (9.3%), of which the commonest was\n                    <jats:italic>Rhizopus oryzae\/arrhizus<\/jats:italic>\n                    (27\/38, 71.1%). Of the 408 cases, 334 (81.9%) patients received antifungal therapy, while 244 (59.8%) had surgery. In cases with a specified outcome, survival rate was 59.1% (228\/386). Based on case reporting, a substantial burden of mucormycosis occurs in North Africa but the disease is rarely reported in most of the sub\u2010Saharan region. Establishing a comprehensive registry for standardised data collection could improve understanding of the epidemiology of mucormycosis in the region.\n                  <\/jats:p>","DOI":"10.1111\/myc.13581","type":"journal-article","created":{"date-parts":[[2023,3,1]],"date-time":"2023-03-01T08:59:55Z","timestamp":1677661195000},"page":"555-562","update-policy":"https:\/\/doi.org\/10.1002\/crossmark_policy","source":"Crossref","is-referenced-by-count":21,"title":["Mucormycosis in Africa: Epidemiology, diagnosis and treatment outcomes"],"prefix":"10.1111","volume":"66","author":[{"ORCID":"https:\/\/orcid.org\/0000-0001-8111-0743","authenticated-orcid":false,"given":"Iriagbonse I.","family":"Osaigbovo","sequence":"first","affiliation":[{"name":"Department of Medical Microbiology, School of Medicine, College of Medical Sciences University of Benin  Benin City Nigeria"},{"name":"Medical Mycology Society of Nigeria  Lagos Nigeria"}],"role":[{"vocabulary":"crossref","role":"author"}]},{"ORCID":"https:\/\/orcid.org\/0000-0002-0509-2480","authenticated-orcid":false,"given":"Bassey E.","family":"Ekeng","sequence":"additional","affiliation":[{"name":"Medical Mycology Society of Nigeria  Lagos Nigeria"},{"name":"Department of Medical Microbiology and Parasitology University of Calabar Teaching Hospital  Calabar Nigeria"}],"role":[{"vocabulary":"crossref","role":"author"}]},{"ORCID":"https:\/\/orcid.org\/0000-0002-6849-1315","authenticated-orcid":false,"given":"Adeyinka A.","family":"Davies","sequence":"additional","affiliation":[{"name":"Medical Mycology Society of Nigeria  Lagos Nigeria"},{"name":"Department of Medical Microbiology and Parasitology Olabisi Onabanjo University Teaching Hospital  Sagamu Nigeria"}],"role":[{"vocabulary":"crossref","role":"author"}]},{"ORCID":"https:\/\/orcid.org\/0000-0003-1488-3345","authenticated-orcid":false,"given":"Rita O.","family":"Oladele","sequence":"additional","affiliation":[{"name":"Medical Mycology Society of Nigeria  Lagos Nigeria"},{"name":"Department of Medical Microbiology and Parasitology, Faculty of Basic Medical Sciences, College of Medicine University of Lagos  Lagos Nigeria"}],"role":[{"vocabulary":"crossref","role":"author"}]}],"member":"311","published-online":{"date-parts":[[2023,3,7]]},"reference":[{"key":"e_1_2_8_2_1","doi-asserted-by":"publisher","DOI":"10.1016\/j.mycres.2007.03.004"},{"key":"e_1_2_8_3_1","doi-asserted-by":"publisher","DOI":"10.1093\/cid\/cir866"},{"key":"e_1_2_8_4_1","first-page":"175","article-title":"Epidemiology and treatment approaches in management of invasive fungal infections","volume":"3","author":"Kriengkauykiat J","year":"2011","journal-title":"Clin Epidemiol"},{"key":"e_1_2_8_5_1","doi-asserted-by":"publisher","DOI":"10.2144\/fsoa-2021-0122"},{"key":"e_1_2_8_6_1","doi-asserted-by":"publisher","DOI":"10.1086\/432579"},{"key":"e_1_2_8_7_1","doi-asserted-by":"publisher","DOI":"10.3390\/jof3040057"},{"key":"e_1_2_8_8_1","doi-asserted-by":"publisher","DOI":"10.1093\/mmy\/myx101"},{"key":"e_1_2_8_9_1","doi-asserted-by":"publisher","DOI":"10.1111\/j.1469-0691.2010.03456.x"},{"key":"e_1_2_8_10_1","doi-asserted-by":"publisher","DOI":"10.1080\/13693780500464930"},{"key":"e_1_2_8_11_1","doi-asserted-by":"publisher","DOI":"10.1093\/mmy\/myx017"},{"key":"e_1_2_8_12_1","doi-asserted-by":"publisher","DOI":"10.1016\/j.cmi.2018.07.011"},{"key":"e_1_2_8_13_1","doi-asserted-by":"publisher","DOI":"10.1111\/myc.13123"},{"key":"e_1_2_8_14_1","unstructured":"Africa.Diabetes report 2000\u20132045.https:\/\/diabetesatlas.org\/data\/en\/region\/2\/afr.htmlAccessed August 28 2022."},{"key":"e_1_2_8_15_1","unstructured":"Middle East and North Africa.Diabetes report 2000\u20132045.https:\/\/diabetesatlas.org\/data\/en\/region\/4\/mena.htmlAccessed August 28 2022."},{"key":"e_1_2_8_16_1","unstructured":"Egypt.Diabetes report 2000\u20132045.https:\/\/diabetesatlas.org\/data\/en\/country\/61\/eg.htmlAccessed August 28 2022."},{"key":"e_1_2_8_17_1","doi-asserted-by":"publisher","DOI":"10.1016\/j.aogh.2015.12.011"},{"key":"e_1_2_8_18_1","unstructured":"Tunisia.Diabetes report 2000\u20132045.https:\/\/diabetesatlas.org\/data\/en\/country\/202\/tn.html. Accessed August 28 2022."},{"key":"e_1_2_8_19_1","unstructured":"Libya.Diabetes report 2000\u20132045.https:\/\/diabetesatlas.org\/data\/en\/country\/113\/ly.html. Accessed August 28 2022."},{"key":"e_1_2_8_20_1","doi-asserted-by":"publisher","DOI":"10.1038\/s41564-022-01172-2"},{"key":"e_1_2_8_21_1","doi-asserted-by":"publisher","DOI":"10.3390\/jof7110985"},{"key":"e_1_2_8_22_1","doi-asserted-by":"publisher","DOI":"10.1093\/cid\/ciz1008"},{"key":"e_1_2_8_23_1","doi-asserted-by":"publisher","DOI":"10.3389\/fmicb.2020.595375"},{"key":"e_1_2_8_24_1","doi-asserted-by":"publisher","DOI":"10.1016\/j.clinmicnews.2022.08.003"},{"key":"e_1_2_8_25_1","doi-asserted-by":"publisher","DOI":"10.1111\/1469-0691.12563"},{"key":"e_1_2_8_26_1","doi-asserted-by":"publisher","DOI":"10.1128\/JCM.01230-21"},{"key":"e_1_2_8_27_1","doi-asserted-by":"publisher","DOI":"10.1136\/jim-2021-002179"},{"key":"e_1_2_8_28_1","doi-asserted-by":"publisher","DOI":"10.1016\/S2666-5247(21)00190-7"},{"key":"e_1_2_8_29_1","doi-asserted-by":"publisher","DOI":"10.1093\/cid\/cir880"},{"key":"e_1_2_8_30_1","doi-asserted-by":"publisher","DOI":"10.1016\/S1473-3099(19)30312-3"},{"key":"e_1_2_8_31_1","doi-asserted-by":"publisher","DOI":"10.1111\/myc.13044"}],"container-title":["Mycoses"],"original-title":[],"language":"en","link":[{"URL":"https:\/\/onlinelibrary.wiley.com\/doi\/pdf\/10.1111\/myc.13581","content-type":"application\/pdf","content-version":"vor","intended-application":"text-mining"},{"URL":"https:\/\/onlinelibrary.wiley.com\/doi\/full-xml\/10.1111\/myc.13581","content-type":"application\/xml","content-version":"vor","intended-application":"text-mining"},{"URL":"https:\/\/onlinelibrary.wiley.com\/doi\/pdf\/10.1111\/myc.13581","content-type":"unspecified","content-version":"vor","intended-application":"similarity-checking"}],"deposited":{"date-parts":[[2023,8,20]],"date-time":"2023-08-20T13:20:28Z","timestamp":1692537628000},"score":1,"resource":{"primary":{"URL":"https:\/\/onlinelibrary.wiley.com\/doi\/10.1111\/myc.13581"}},"subtitle":[],"short-title":[],"issued":{"date-parts":[[2023,3,7]]},"references-count":30,"journal-issue":{"issue":"7","published-print":{"date-parts":[[2023,7]]}},"alternative-id":["10.1111\/myc.13581"],"URL":"https:\/\/doi.org\/10.1111\/myc.13581","archive":["Portico"],"relation":{},"ISSN":["0933-7407","1439-0507"],"issn-type":[{"value":"0933-7407","type":"print"},{"value":"1439-0507","type":"electronic"}],"subject":[],"published":{"date-parts":[[2023,3,7]]},"assertion":[{"value":"2022-12-11","order":0,"name":"received","label":"Received","group":{"name":"publication_history","label":"Publication History"}},{"value":"2023-02-25","order":1,"name":"accepted","label":"Accepted","group":{"name":"publication_history","label":"Publication History"}},{"value":"2023-03-07","order":2,"name":"published","label":"Published","group":{"name":"publication_history","label":"Publication History"}}]}}