{"status":"ok","message-type":"work","message-version":"1.0.0","message":{"indexed":{"date-parts":[[2025,7,30]],"date-time":"2025-07-30T12:41:48Z","timestamp":1753879308753,"version":"3.41.2"},"reference-count":20,"publisher":"Wiley","issue":"4","license":[{"start":{"date-parts":[[2024,4,3]],"date-time":"2024-04-03T00:00:00Z","timestamp":1712102400000},"content-version":"vor","delay-in-days":2,"URL":"http:\/\/onlinelibrary.wiley.com\/termsAndConditions#vor"}],"content-domain":{"domain":["onlinelibrary.wiley.com"],"crossmark-restriction":true},"short-container-title":["Mycoses"],"published-print":{"date-parts":[[2024,4]]},"abstract":"<jats:title>Abstract<\/jats:title><jats:sec><jats:title>Background<\/jats:title><jats:p>Psoriatic patients may experience the coexistence of onychomycosis (OM). However, the evaluation of OM in psoriatics has been hindered by potential clinical differences from OM in non\u2010psoriatics.<\/jats:p><\/jats:sec><jats:sec><jats:title>Objective<\/jats:title><jats:p>To assess and compare dermoscopic features between toenail OM in psoriatic and in non\u2010psoriatic patients.<\/jats:p><\/jats:sec><jats:sec><jats:title>Patients and Methods<\/jats:title><jats:p>Between September 2020 and September 2023, dermoscopy was conducted on 183 affected toenails by OM in psoriatics and 232 affected toenails by OM in non\u2010psoriatics in two centres. The dermoscopic characteristics were compared using the Chi\u2010squared test.<\/jats:p><\/jats:sec><jats:sec><jats:title>Results<\/jats:title><jats:p>Among toenail OM cases in psoriatic subjects, the most prevalent dermoscopic features included pitting (147\/183, 80.33%) and subungual hyperkeratosis (118\/183, 64.48%). Conversely, toenail OM in non\u2010psoriatics was characterized by subungual hyperkeratosis (175\/232, 75.43%) and nail spikes (139\/232, 59.91%). Comparative analysis revealed a significantly higher occurrence of pitting (80.33% vs. 15.96%, <jats:italic>p<\/jats:italic>\u2009&lt;\u2009.001), periungual telangiectasis (22.40% vs. 4.74%, <jats:italic>p<\/jats:italic>\u2009&lt;\u2009.001), oil patches (12.57% vs. 0.43%,<jats:italic>p<\/jats:italic>\u2009&lt;\u2009.001) and transverse grooves (43.72% vs. 28.45%,<jats:italic>p<\/jats:italic>\u2009&lt;\u2009.01) in toenail OM in psoriatics. Furthermore, toenail OM in psoriatics exhibited a significantly lower frequency of yellow structureless area (13.11% vs. 42.67%, <jats:italic>p<\/jats:italic>\u2009&lt;\u2009.001), nail spikes (43.17% vs. 59.91%, <jats:italic>p<\/jats:italic>\u2009&lt;\u2009.01), ruin appearance of sulphur nugget (8.20% vs. 31.03%, <jats:italic>p<\/jats:italic>\u2009&lt;\u2009.001), dotted\/blocky haemorrhage (6.01% vs. 20.69%,<jats:italic>p<\/jats:italic>\u2009&lt;\u2009.001) and partial onycholysis (32.79% vs. 46.98%, <jats:italic>p<\/jats:italic>\u2009&lt;\u2009.01).<\/jats:p><\/jats:sec><jats:sec><jats:title>Conclusions<\/jats:title><jats:p>Dermoscopic features of toenail OM in psoriatic and non\u2010psoriatic patients exhibit notable differences. OM in psoriatics shows a higher frequency of pitting and periungual telangiectasis, while a lower frequency of yellow structureless areas and nail spikes under dermoscopy.<\/jats:p><\/jats:sec>","DOI":"10.1111\/myc.13721","type":"journal-article","created":{"date-parts":[[2024,4,4]],"date-time":"2024-04-04T04:14:47Z","timestamp":1712204087000},"update-policy":"https:\/\/doi.org\/10.1002\/crossmark_policy","source":"Crossref","is-referenced-by-count":1,"title":["Comparison of dermoscopic characteristics on toenail onychomycosis in psoriatic and non\u2010psoriatic patients: A prospective study"],"prefix":"10.1111","volume":"67","author":[{"ORCID":"https:\/\/orcid.org\/0000-0003-4085-3086","authenticated-orcid":false,"given":"Shiqi","family":"Wang","sequence":"first","affiliation":[{"name":"Department of Dermatology, Venereology and Cosmetology, Beijing Chaoyang Hospital Capital Medical University  Beijing China"}],"role":[{"role":"author","vocabulary":"crossref"}]},{"given":"Wei","family":"Chen","sequence":"additional","affiliation":[{"name":"Department of Dermatology Peking University First Hospital  Beijing China"},{"name":"National Clinical Research Center for Skin and Immune Diseases  Beijing China"},{"name":"Research Center for Medical Mycology, Peking University  Beijing China"},{"name":"Beijing Key Laboratory of Molecular Diagnosis of Dermatoses  Beijing China"},{"name":"NMPA Key Laboratory for Quality Control and Evaluation of Cosmetics  Beijing China"}],"role":[{"role":"author","vocabulary":"crossref"}]},{"given":"Fang","family":"Liu","sequence":"additional","affiliation":[{"name":"Department of Dermatology, Venereology and Cosmetology, Beijing Chaoyang Hospital Capital Medical University  Beijing China"}],"role":[{"role":"author","vocabulary":"crossref"}]},{"given":"Ruoyu","family":"Li","sequence":"additional","affiliation":[{"name":"Department of Dermatology Peking University First Hospital  Beijing China"},{"name":"National Clinical Research Center for Skin and Immune Diseases  Beijing China"},{"name":"Research Center for Medical Mycology, Peking University  Beijing China"},{"name":"Beijing Key Laboratory of Molecular Diagnosis of Dermatoses  Beijing China"},{"name":"NMPA Key Laboratory for Quality Control and Evaluation of Cosmetics  Beijing China"}],"role":[{"role":"author","vocabulary":"crossref"}]}],"member":"311","published-online":{"date-parts":[[2024,4,3]]},"reference":[{"key":"e_1_2_10_2_1","doi-asserted-by":"publisher","DOI":"10.1177\/1203475417716362"},{"key":"e_1_2_10_3_1","doi-asserted-by":"publisher","DOI":"10.1111\/j.1439-0507.2009.01726.x"},{"key":"e_1_2_10_4_1","unstructured":"KumarPS SangamithraiS ChitralekhaS BupeshG.Comparative study on prevalence of onychomycosis in psoriatic and non psoriatic patients attending skin OPD in Tertiary Care Hospital Chennai Tamilnadu 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evaluation of distal and lateral subungual onychomycosis: a cross\u2010sectional study in Lebanon","volume":"5","author":"Maatouk I","year":"2019","journal-title":"Curr Med 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