{"status":"ok","message-type":"work","message-version":"1.0.0","message":{"indexed":{"date-parts":[[2026,11,4]],"date-time":"2026-11-04T20:35:52Z","timestamp":1793824552289,"version":"4.6.1"},"reference-count":24,"publisher":"Wiley","issue":"5","license":[{"start":{"date-parts":[[2024,5,23]],"date-time":"2024-05-23T00:00:00Z","timestamp":1716422400000},"content-version":"vor","delay-in-days":22,"URL":"http:\/\/onlinelibrary.wiley.com\/termsAndConditions#vor"}],"content-domain":{"domain":["onlinelibrary.wiley.com"],"crossmark-restriction":true},"short-container-title":["Mycoses"],"published-print":{"date-parts":[[2024,5]]},"abstract":"<jats:title>Abstract<\/jats:title>\n                  <jats:sec>\n                    <jats:title>Background<\/jats:title>\n                    <jats:p>Chronic pulmonary aspergillosis (CPA) is known to complicate patients with post\u2010tubercular lung disease. However, some evidence suggests that CPA might co\u2010exist in patients with newly\u2010diagnosed pulmonary tuberculosis (P.TB) at diagnosis and also develop during therapy. The objective of this study was to confirm the presence of CPA in newly diagnosed P.TB at baseline and at the end\u2010of\u2010TB\u2010therapy.<\/jats:p>\n                  <\/jats:sec>\n                  <jats:sec>\n                    <jats:title>Materials and Methods<\/jats:title>\n                    <jats:p>\n                      This prospective longitudinal study included newly diagnosed P.TB patients, followed up at third month and end\u2010of\u2010TB\u2010therapy with symptom assessment, anti\u2010\n                      <jats:italic>Aspergillus<\/jats:italic>\n                      IgG antibody and imaging of chest for diagnosing CPA.\n                    <\/jats:p>\n                  <\/jats:sec>\n                  <jats:sec>\n                    <jats:title>Results<\/jats:title>\n                    <jats:p>\n                      We recruited 255 patients at baseline out of which 158 (62%) completed their follow\u2010up. Anti\u2010\n                      <jats:italic>Aspergillus<\/jats:italic>\n                      IgG was positive in 11.1% at baseline and 27.8% at end\u2010of\u2010TB\u2010therapy. Overall, proven CPA was diagnosed in 7% at baseline and 14.5% at the end\u2010of\u2010TB\u2010therapy. Around 6% patients had evidence of aspergilloma in CT chest at the end\u2010of\u2010TB\u2010therapy.\n                    <\/jats:p>\n                  <\/jats:sec>\n                  <jats:sec>\n                    <jats:title>Conclusions<\/jats:title>\n                    <jats:p>CPA can be present in newly diagnosed P.TB patients at diagnosis and also develop during anti\u2010tubercular treatment. Patients with persistent symptoms or developing new symptoms during treatment for P.TB should be evaluated for CPA. Whether patients with concomitant P.TB and CPA, while receiving antitubercular therapy, need additional antifungal therapy, needs to be evaluated in future studies.<\/jats:p>\n                  <\/jats:sec>","DOI":"10.1111\/myc.13747","type":"journal-article","created":{"date-parts":[[2024,5,23]],"date-time":"2024-05-23T22:51:36Z","timestamp":1716504696000},"update-policy":"https:\/\/doi.org\/10.1002\/crossmark_policy","source":"Crossref","is-referenced-by-count":14,"title":["Chronic pulmonary aspergillosis incidence in newly detected pulmonary tuberculosis cases during follow\u2010up"],"prefix":"10.1111","volume":"67","author":[{"given":"Dhouli","family":"Jha","sequence":"first","affiliation":[{"name":"Department of Medicine All India Institute of Medical Sciences  New Delhi India"}],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Umesh","family":"Kumar","sequence":"additional","affiliation":[{"name":"Nehru Nagar Chest and TB Hospital  New Delhi India"}],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Ved Prakash","family":"Meena","sequence":"additional","affiliation":[{"name":"Department of Medicine All India Institute of Medical Sciences  New Delhi India"}],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Prayas","family":"Sethi","sequence":"additional","affiliation":[{"name":"Department of Medicine All India Institute of Medical Sciences  New Delhi India"}],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Amandeep","family":"Singh","sequence":"additional","affiliation":[{"name":"Department of Medicine All India Institute of Medical Sciences  New Delhi India"}],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Neeraj","family":"Nischal","sequence":"additional","affiliation":[{"name":"Department of Medicine All India Institute of Medical Sciences  New Delhi 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B.","family":"Singh","sequence":"additional","affiliation":[{"name":"Department of Microbiology All India Institute of Medical Sciences  New Delhi India"}],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Sanjeev","family":"Sinha","sequence":"additional","affiliation":[{"name":"Department of Medicine All India Institute of Medical Sciences  New Delhi India"}],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Anant","family":"Mohan","sequence":"additional","affiliation":[{"name":"Department of Pulmonary, Critical Care and Sleep Medicine All India Institute of Medical Sciences  New Delhi India"}],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Naveet","family":"Wig","sequence":"additional","affiliation":[{"name":"Department of Medicine All India Institute of Medical Sciences  New Delhi India"}],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Sushil Kumar","family":"Kabra","sequence":"additional","affiliation":[{"name":"Department of Pediatrics All India Institute of Medical Sciences  New Delhi India"}],"role":[{"vocabulary":"crossref","role":"author"}]},{"ORCID":"https:\/\/orcid.org\/0000-0002-9434-5338","authenticated-orcid":false,"given":"Animesh","family":"Ray","sequence":"additional","affiliation":[{"name":"Department of Medicine All India Institute of Medical Sciences  New Delhi India"}],"role":[{"vocabulary":"crossref","role":"author"}]}],"member":"311","published-online":{"date-parts":[[2024,5,23]]},"reference":[{"key":"e_1_2_11_2_1","unstructured":"Chronic pulmonary aspergillosis: rationale and clinical guidelines for diagnosis and management.2023.https:\/\/pubmed.ncbi.nlm.nih.gov\/26699723\/"},{"key":"e_1_2_11_3_1","doi-asserted-by":"publisher","DOI":"10.3390\/jof8040400"},{"key":"e_1_2_11_4_1","doi-asserted-by":"publisher","DOI":"10.1016\/j.ijregi.2022.11.005"},{"key":"e_1_2_11_5_1","unstructured":"Underlying conditions in chronic pulmonary aspergillosis including simple 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factors of chronic pulmonary aspergillosis in patients with etiology positive pulmonary tuberculosis","volume":"30","author":"Wang F","year":"2023","journal-title":"Altern Ther Health 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